General Information of Xenobiotics (ID: XEO04770)
Xenobiotics Name
Pyrrhocoricin
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
Structure
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3D MOL 2D MOL
PubChem CID
16131340
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Beta-lactamase (blaB) DME Info Salmonella enterica [1]
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [1]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [1]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [1]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [1]
Unclear metabolic mechanism (DME-unclear) DME Info Salmonella enterica [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Salmonella enterica [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Salmonella enterica [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Beta-lactamase (blaB) DME Info MIC = 5 microM [1]
Cytochrome P450 102A1 (cyp102) DME Info MIC > 80 microM [1]
Cytochrome P450 MEG (cyp106) DME Info MIC > 80 microM [1]
Cytochrome P450 21A2 (cyp21) DME Info MIC > 80 microM [1]
Cytochrome P450 BM3 (cypBM3) DME Info MIC > 80 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 5 microM [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 5 microM [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 5 microM [1]
References
1 Structural studies on the forward and reverse binding modes of peptides to the chaperone DnaK. J Mol Biol. 2013 Jul 24;425(14):2463-79.

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