Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1664)
DME Name Cytochrome P450 monooxygenase 51A (cyp51A), Aspergillus fumigatus DME Info
UniProt ID
CP51A_ASPFU
EC Number    EC: 1.14.14.154     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
Oxygen paired donor oxidoreductase
Flavin/flavoprotein donor oxidoreductase
EC: 1.14.14.154
Lineage    Species: Aspergillus fumigatus     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Fungi
Phylum: Ascomycota
Class: Eurotiomycetes
Order: Eurotiales
Family: Aspergillaceae
Genus: Aspergillus
Species: Aspergillus fumigatus
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:      55 Xenobiotics
                              Adenoregulin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02136   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Adenoregulin inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 125 ug/ml) [1]
                              Androctonin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02224   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Androctonin inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [2]
                              Anopheles cecropin-A amidated isoform Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02230   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Anopheles cecropin-A amidated isoform inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 5-10 microM) [3], [4]
                              Antifungal protein Pf-AFP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02252   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antifungal protein Pf-AFP1 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [5]
                              Antifungal protein Pr-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02255   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antifungal protein Pr-2 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [6]
                              Antimicrobial peptide HP(2-20) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02283   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide HP(2-20) inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC > 50 ug/ml) [7]
                              Arachnid gomesin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03497   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Arachnid gomesin inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 1.6-3.15 microM) [8]
                              ARD1 Mutant ETD130 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03327   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD130 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD131 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03328   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD131 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD132 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03329   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD132 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD133 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03330   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD133 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD134 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03331   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD134 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD135 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03332   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD135 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD140 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03333   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD140 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD150 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03334   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD150 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD151 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03335   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD151 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD152 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03336   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD152 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD154 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03337   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD154 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD156 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03338   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD156 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              ARD1 Mutant ETD179 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03339   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation ARD1 Mutant ETD179 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [9]
                              Cecropin1 peptide derivative Px-cec1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04767   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin1 peptide derivative Px-cec1 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 16.0 ug/ml) [10]
                              Colutellin-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02906   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Colutellin-A inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [11]
                              Defensin ARD1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03102   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin ARD1 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 12.5 ug/ml) [9]
                              Defensin heliomicin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03109   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin heliomicin inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 6-12 microM) [12], [13]
                              Dermaseptin B1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03158   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dermaseptin B1 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 125 ug/ml) [14], [15]
                              Dermaseptin DS1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03151   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dermaseptin DS1 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 100 ug/ml) [16], [14]
                              Dermaseptin DS2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03153   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dermaseptin DS2 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [14]
                              Dermaseptin DS3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03154   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dermaseptin DS3 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [14], [17]
                              HP(2-20) analogue Anal 1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02207   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 1 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC > 50 ug/ml) [7]
                              HP(2-20) analogue Anal 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02208   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 2 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC > 50 ug/ml) [7]
                              HP(2-20) analogue Anal 3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02209   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 3 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 25 ug/ml) [7]
                              HP(2-20) analogue Anal 4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02210   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 4 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC > 50 ug/ml) [7]
                              HP(2-20) analogue Anal 5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02211   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 5 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC > 50 ug/ml) [7]
                              HP(2-20) analogue Anal 6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02212   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 6 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 50-25 ug/ml) [7]
                              HP(2-20) analogue Anal 7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02213   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 7 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 50-25 ug/ml) [7]
                              hrVS-1-derived peptide CGA47-60 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02803   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation hrVS-1-derived peptide CGA47-60 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 50 microM) [18]
                              hrVS-1-derived peptide CGA47-70 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02804   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation hrVS-1-derived peptide CGA47-70 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 30 microM) [18]
                              Human drosomycin-like defensin DLD Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03597   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Human drosomycin-like defensin DLD inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 6.25 microM) [19]
                              Human hepcidin Hepc20 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03598   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Human hepcidin Hepc20 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [20]
                              Human hepcidin Hepc25 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03599   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Human hepcidin Hepc25 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [20]
                              Insect attacin-C Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02333   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect attacin-C inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC > 200 microM) [21]
                              Lactoferricin B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03776   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lactoferricin B inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [22]
                              Penaeidin-2d Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04506   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Penaeidin-2d inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC > 20 microM) [23], [24]
                              Penaeidin-3a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04507   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Penaeidin-3a inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC > 20 microM) [25]
                              Phlebotomus duboscqi defensin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04560   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Phlebotomus duboscqi defensin inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 12.5-25 microM) [26]
                              Piscidin Pis-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04613   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Piscidin Pis-2 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 50-100 microM) [27]
                              Px-cec1 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04766   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Px-cec1 peptide inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 16.0 microM) [10]
                              Skin peptide tyrosine-tyrosine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04950   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Skin peptide tyrosine-tyrosine inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 80 ug/ml) [28], [29]
                              Spheniscin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04971   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Spheniscin-2 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 3-6 microM) [30], [31]
                              Spider gomesin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03498   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Spider gomesin inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 1.6-3.15 microM) [8]
                              Stomoxyn Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04995   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Stomoxyn inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 50-100 microM) [32], [33]
                              Tritrpticin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05179   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tritrpticin inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 250 ug/ml) [34], [35]
                              Trp- and Arg-rich peptide 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04532   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Trp- and Arg-rich peptide 2 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [34]
                              Vasostatin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05229   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Vasostatin-1 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 5 microM) [18]
                              Venom antimicrobial peptide-9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05231   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Venom antimicrobial peptide-9 inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus (MIC = 8.3 microM) [36]
      Pharmaceutical Agent(s)
                  Drug in Phase 1 Clinical Trial Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Chitosan Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00621   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 1/2
                                 DME Modulation Chitosan inhibits the drug-metabolizing activity of Cytochrome P450 monooxygenase 51A (cyp51A) from Aspergillus fumigatus [37]
References
1 The amphiphilic peptide adenoregulin enhances agonist binding to A1-adenosine receptors and [35S]GTP gamma S to brain membranes. Cell Mol Neurobiol. 1995 Aug;15(4):465-93.
2 Characterization of novel cysteine-rich antimicrobial peptides from scorpion blood. J Biol Chem. 1996 Nov 22;271(47):29537-44.
3 Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae. Insect Mol Biol. 2000 Feb;9(1):75-84.
4 Genomic organization and regulation of three cecropin genes in Anopheles gambiae. Insect Mol Biol. 2002 Dec;11(6):517-25.
5 An antifungal peptide from passion fruit (Passiflora edulis) seeds with similarities to 2S albumin proteins. Biochim Biophys Acta. 2006 Jun;1764(6):1141-6.
6 Antifungal mechanism of a novel antifungal protein from pumpkin rinds against various fungal pathogens. J Agric Food Chem. 2009 Oct 14;57(19):9299-304.
7 Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori. Biochem J. 2006 Feb 15;394(Pt 1):105-14.
8 Isolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family. J Biol Chem. 2000 Oct 27;275(43):33464-70.
9 Lead optimization of antifungal peptides with 3D NMR structures analysis. Protein Sci. 2004 Mar;13(3):703-13.
10 cDNA cloning and characterization of the antibacterial peptide cecropin 1 from the diamondback moth, Plutella xylostella L. Protein Expr Purif. 2012 Oct;85(2):230-8.
11 Colutellin A, an immunosuppressive peptide from Colletotrichum dematium. Microbiology. 2008 Jul;154(Pt 7):1973-1979.
12 Insect immunityIsolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity. J Biol Chem. 1999 Apr 2;274(14):9320-6.
13 Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities. Biochemistry. 2001 Oct 9;40(40):11995-2003.
14 Isolation and structure of novel defensive peptides from frog skin. Eur J Biochem. 1994 Jan 15;219(1-2):145-54.
15 Precursors of vertebrate peptide antibiotics dermaseptin b and adenoregulin have extensive sequence identities with precursors of opioid peptides dermorphin, dermenkephalin, and deltorphins. J Biol Chem. 1994 Jul 8;269(27):17847-52.
16 Isolation, amino acid sequence, and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skin. Biochemistry. 1991 Sep 10;30(36):8824-30.
17 Selective cytotoxicity of dermaseptin S3 toward intraerythrocytic Plasmodium falciparum and the underlying molecular basis. J Biol Chem. 1997 Dec 12;272(50):31609-16.
18 Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A. J Biol Chem. 2000 Apr 14;275(15):10745-53.
19 Drosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity. Antimicrob Agents Chemother. 2008 Apr;52(4):1407-12.
20 LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett. 2000 Sep 1;480(2-3):147-50.
21 Primary structure and in vitro antibacterial properties of the Drosophila melanogaster attacin C Pro-domain. J Biol Chem. 2004 Apr 9;279(15):14853-9.
22 Effects of lactoferricin B against keratitis-associated fungal biofilms. J Infect Chemother. 2012 Oct;18(5):698-703.
23 Diversity of the penaeidin antimicrobial peptides in two shrimp species. Immunogenetics. 2002 Sep;54(6):442-5.
24 Recombinant expression and range of activity of penaeidins, antimicrobial peptides from penaeid shrimp. Eur J Biochem. 1999 Dec;266(2):335-46.
25 Solution structure of the recombinant penaeidin-3, a shrimp antimicrobial peptide. J Biol Chem. 2003 Sep 19;278(38):36859-67.
26 Characterization of a defensin from the sand fly Phlebotomus duboscqi induced by challenge with bacteria or the protozoan parasite Leishmania major. Infect Immun. 2004 Dec;72(12):7140-6.
27 Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem. 2002 Feb 15;277(7):5030-9.
28 Skin peptide tyrosine-tyrosine, a member of the pancreatic polypeptide family: isolation, structure, synthesis, and endocrine activity. Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10295-9.
29 Broad spectrum antibiotic activity of the skin-PYY. FEBS Lett. 1996 Feb 19;380(3):237-40.
30 Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus. J Biol Chem. 2003 Dec 19;278(51):51053-8.
31 Solution structure of spheniscin, a beta-defensin from the penguin stomach. J Biol Chem. 2004 Jul 16;279(29):30433-9.
32 Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation. Biopolymers. 2006 Feb 5;81(2):92-103.
33 Epithelial innate immunityA novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans. J Biol Chem. 2002 Dec 20;277(51):49921-6.
34 Antimicrobial activity of a 13 amino acid tryptophan-rich peptide derived from a putative porcine precursor protein of a novel family of antibacterial peptides. FEBS Lett. 1996 Jul 15;390(1):95-8.
35 Structure of the antimicrobial peptide tritrpticin bound to micelles: a distinct membrane-bound peptide fold. Biochemistry. 1999 Dec 21;38(51):16749-55.
36 Structural and functional characterization of two genetically related meucin peptides highlights evolutionary divergence and convergence in antimicrobial peptides. FASEB J. 2009 Apr;23(4):1230-45.
37 Aspergillus fumigatus DBM 4057 biofilm formation is inhibited by chitosan, in contrast to baicalein and rhamnolipid. World J Microbiol Biotechnol. 2016 Nov;32(11):187.

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