Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03158)
Xenobiotics Name	Dermaseptin B1
Xenobiotics Type	Amino Acid(s), Peptide(s) or Protein(s)
Classification	Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
	Azoreductase (azoR)	DME Info	Escherichia coli	[1], [2]
	L,D-carboxypeptidase A (ldcA)	DME Info	Escherichia coli	[1], [2]
	Beta-lactamase (blaB)	DME Info	Escherichia coli	[1], [2]
	Chloramphenicolase (chlR)	DME Info	Escherichia coli	[1], [2]
	Glycoside hydrolase (cscA)	DME Info	Escherichia coli	[1], [2]
	NADPH-dependent curcumin reductase (curA)	DME Info	Escherichia coli	[1], [2]
	Cytochrome P450 monooxygenase 51A (cyp51A)	DME Info	Aspergillus fumigatus	[1], [2]
	Unclear metabolic mechanism (DME-unclear)	DME Info	Escherichia coli	[1], [2]
	Glutamate decarboxylase (gadB)	DME Info	Escherichia coli	[1], [2]
	D-Lactate dehydrogenase (ldhA)	DME Info	Escherichia coli	[1], [2]
	Molybdopterin-dependent enzyme (molD)	DME Info	Escherichia coli	[1], [2]
	Glutamate racemase (MurI)	DME Info	Escherichia coli	[1], [2]
	N-ethylmaleimide reductase (nemA)	DME Info	Escherichia coli	[1], [2]
	Oxygen-insensitive NADPH nitroreductase A (nfsA)	DME Info	Escherichia coli	[1], [2]
	Oxygen-insensitive NADPH nitroreductase B (nfsB)	DME Info	Escherichia coli	[1], [2]
	NADH dehydrogenase (nuoE)	DME Info	Streptomyces griseus	[1], [2]
	Tyramine oxidase (tynA)	DME Info	Escherichia coli	[1], [2]
	Beta-glucuronidase (uidA)	DME Info	Escherichia coli	[1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data	Azoreductase (azoR)	DME Info	MIC = 15 ug/ml	[1], [2]
	L,D-carboxypeptidase A (ldcA)	DME Info	MIC = 15 ug/ml	[1], [2]
	Beta-lactamase (blaB)	DME Info	MIC = 15 ug/ml	[1], [2]
	Chloramphenicolase (chlR)	DME Info	MIC = 15 ug/ml	[1], [2]
	Glycoside hydrolase (cscA)	DME Info	MIC = 15 ug/ml	[1], [2]
	NADPH-dependent curcumin reductase (curA)	DME Info	MIC = 15 ug/ml	[1], [2]
	Cytochrome P450 monooxygenase 51A (cyp51A)	DME Info	MIC = 125 ug/ml	[1], [2]
	Unclear metabolic mechanism (DME-unclear)	DME Info	MIC = 15 ug/ml	[1], [2]
	Glutamate decarboxylase (gadB)	DME Info	MIC = 15 ug/ml	[1], [2]
	D-Lactate dehydrogenase (ldhA)	DME Info	MIC = 15 ug/ml	[1], [2]
	Molybdopterin-dependent enzyme (molD)	DME Info	MIC = 15 ug/ml	[1], [2]
	Glutamate racemase (MurI)	DME Info	MIC = 15 ug/ml	[1], [2]
	N-ethylmaleimide reductase (nemA)	DME Info	MIC = 15 ug/ml	[1], [2]
	Oxygen-insensitive NADPH nitroreductase A (nfsA)	DME Info	MIC = 15 ug/ml	[1], [2]
	Oxygen-insensitive NADPH nitroreductase B (nfsB)	DME Info	MIC = 15 ug/ml	[1], [2]
	NADH dehydrogenase (nuoE)	DME Info	MIC = 15 ug/ml	[1], [2]
	Tyramine oxidase (tynA)	DME Info	MIC = 15 ug/ml	[1], [2]
	Beta-glucuronidase (uidA)	DME Info	MIC = 15 ug/ml	[1], [2]

References
1	Isolation and structure of novel defensive peptides from frog skin. Eur J Biochem. 1994 Jan 15;219(1-2):145-54.
2	Precursors of vertebrate peptide antibiotics dermaseptin b and adenoregulin have extensive sequence identities with precursors of opioid peptides dermorphin, dermenkephalin, and deltorphins. J Biol Chem. 1994 Jul 8;269(27):17847-52.

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