Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03151)
Xenobiotics Name
Dermaseptin DS1
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Cytochrome P450 monooxygenase 51A (cyp51A) DME Info Aspergillus fumigatus [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 5 ug/ml [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 5 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 5 ug/ml [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 5 ug/ml [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 5 ug/ml [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 5 ug/ml [1], [2]
Cytochrome P450 monooxygenase 51A (cyp51A) DME Info MIC = 100 ug/ml [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 5 ug/ml [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 5 ug/ml [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 5 ug/ml [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 5 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC = 5 ug/ml [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 5 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 5 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 5 ug/ml [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 5 ug/ml [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 5 ug/ml [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 5 ug/ml [1], [2]
References
1 Isolation, amino acid sequence, and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skin. Biochemistry. 1991 Sep 10;30(36):8824-30.
2 Isolation and structure of novel defensive peptides from frog skin. Eur J Biochem. 1994 Jan 15;219(1-2):145-54.

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