Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00621)
Xenobiotics Name
Chitosan
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 1 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
71853
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Cytochrome P450 monooxygenase 51A (cyp51A) DME Info Aspergillus fumigatus [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
DME(s) Induced by This Xenobiotics
Alkaline phosphatase (ALPL) DME Info Homo sapiens [3]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [4]
References
1 Sugar fatty acid esters inhibit biofilm formation by food-borne pathogenic bacteria. Int J Food Microbiol. 2010 Mar 31;138(1-2):176-80.
2 Aspergillus fumigatus DBM 4057 biofilm formation is inhibited by chitosan, in contrast to baicalein and rhamnolipid. World J Microbiol Biotechnol. 2016 Nov;32(11):187.
3 Improving effects of chitosan nanofiber scaffolds on osteoblast proliferation and maturation. Int J Nanomedicine. 2014 Sep 9;9:4293-304.
4 Uptake and cytotoxicity of chitosan nanoparticles in human liver cells. Toxicol Appl Pharmacol. 2010 Dec 1;249(2):148-57.

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