General Information of This Metabolic Reaction (MR) (ID: MR006962)
Formula
SVG example
Reactant 3-(Phenyl)propionic acid Product Hippuric acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003834 3-(4-Hydroxyphenyl) propionic acid 3-Phenylpropionic acid Unclear BE-14348A [1]
MR009196 3-(3'-Hydroxyphenyl)propanoic acid 3-(phenyl)propanoic acid Oxidation - Dehydroxylation 3,4-Dihydroxycinnamic Acid [2]
MR006961 3-(4-Hydroxyphenyl)propionic acid 3-(Phenyl)propionic acid Unclear CCG-208408 [3]
MR004313 3-(4'-hydroxyphenyl)propionic acid 3-Phenylpropionic acid Reduction - Dehydroxylation Naringin [4]
MR004497 3-(3'-Hydroxyphenyl)propionic acid 3-(phenyl)propionic acid Reduction - Dehydroxylation VS-12343 [5]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003835 3-Phenylpropionic acid Benzoic acid Unclear BE-14348A [1]
MR009197 3-(phenyl)propanoic acid 3-(phenyl)acetic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [2]
MR004498 3-(phenyl)propionic acid Phenylacetic acid Unclear VS-12343 [5]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010230 Isocarboxazid Hippuric acid Unclear - Unclear Isocarboxazid [6]
MR007547 Benzylamine M16 Benzylamine M1 Unclear Benzylamine [7]
MR004754 Midostaurin Metabolite P6 Midostaurin Metabolite P6B Unclear Midostaurin [8]
MR005014 4-Trifluoromethylphenol Hippuric acid Oxidation - O-dealkylation Fluoxetine hydrochloride [9]
MR000219 Benzoic acid Hippuric acid Conjugation - Glycine Conjugation Amphetamine [10]
MR003837 Benzoic acid Hippuric acid Unclear BE-14348A [1]
MR006885 Phenylacetone Hippuric acid Unclear Lisdexamfetamine [11]
MR005290 Cinnamic acid Metabolite Hippuric acid Unclear Cinnamic acid [12]
MR009199 Benzoic acid Hippuric acid Conjugation - Glycination 3,4-Dihydroxycinnamic Acid [2]
MR013577 4'-hydroxybenzoic acid Hippuric acid Unclear Epigallocatechin gallate [13]
⏷ Show the Full List of MR
References
1 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
2 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
3 Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. Eur J Nutr. 2018 Feb;57(1):231-242.
4 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity
5 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
6 DrugBank(Pharmacology-Metabolism):Isocarboxazid
7 Bioactivation of benzylamine to reactive intermediates in rodents: formation of glutathione, glutamate, and peptide conjugates
8 Midostaurin, a novel protein kinase inhibitor for the treatment of acute myelogenous leukemia: insights from human absorption, metabolism, and excretion studies of a BDDCS II drug. Drug Metab Dispos. 2017 May;45(5):540-555.
9 DrugBank(Pharmacology-Metabolism):Fluoxetine hydrochloride
10 DrugBank(Pharmacology-Metabolism)Amphetamine
11 Preclinical pharmacokinetics, pharmacology and toxicology of lisdexamfetamine: a novel d-amphetamine pro-drug. Neuropharmacology. 2014 Dec;87:41-50.
12 Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose
13 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate

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