Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004498)
Formula
SVG example
Reactant 3-(phenyl)propionic acid Product Phenylacetic acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003834 3-(4-Hydroxyphenyl) propionic acid 3-Phenylpropionic acid Unclear BE-14348A [1]
MR009196 3-(3'-Hydroxyphenyl)propanoic acid 3-(phenyl)propanoic acid Oxidation - Dehydroxylation 3,4-Dihydroxycinnamic Acid [2]
MR006961 3-(4-Hydroxyphenyl)propionic acid 3-(Phenyl)propionic acid Unclear CCG-208408 [3]
MR004313 3-(4'-hydroxyphenyl)propionic acid 3-Phenylpropionic acid Reduction - Dehydroxylation Naringin [4]
MR004497 3-(3'-Hydroxyphenyl)propionic acid 3-(phenyl)propionic acid Reduction - Dehydroxylation VS-12343 [5]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003835 3-Phenylpropionic acid Benzoic acid Unclear BE-14348A [1]
MR006962 3-(Phenyl)propionic acid Hippuric acid Unclear CCG-208408 [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007824 Ipratropium Phenylacetic acid Hydrolysis - Hydrolysis Ipratropium [6]
MR008132 Penicillin Phenylacetic acid Unclear - Unclear Penicillin [7]
MR008108 Penicillin G Sodium Phenyl acetic acid Hydrolysis - Hydrolysis Penicillin G Sodium [8]
MR002019 Phenelzine Phenylacetic acid Hydrolysis - Hydrolysis Phenelzine [9]
MR005608 Sodium phenylbutyrate Phenylacetic acid Oxidation - Oxidationn Sodium phenylbutyrate [10]
MR002015 Phenethylamine Phenylacetic acid Unclear Phenelzine [9]
MR004490 3'-Hydroxyphenylacetic acid Phenylacetic acid Unclear VS-12343 [5]
⏷ Show the Full List of MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009198 3-(phenyl)acetic acid Benzoic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [2]
References
1 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
2 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
3 Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. Eur J Nutr. 2018 Feb;57(1):231-242.
4 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity
5 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
6 Ipratropium bromide: drug metabolism and pharmacokinetics
7 Ligand-induced conformational change in penicillin acylase
8 A breakthrough in enzyme technology to fight penicillin resistance-industrial application of penicillin amidase
9 Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review J Psychiatry Neurosci. 1992 Nov;17(5):206-14.
10 DrugBank(Pharmacology-Metabolism):Sodium phenylbutyrate

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