Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007654)
Formula
SVG example
N-Decarboxylation
Reactant Putrescine Product Spermidine
Reactant Info Product Info
Metabolic Type Other reaction - N-Decarboxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007655 Putrescine -aminobutyric acid Unclear Putrescine [1]
MR007653 Putrescine Spermine Other reaction - Decarboxylation Putrescine [1]
MR003077 Putrescine MTA Unclear Agmatine [2]
MR012737 Putrescine Y-amino-butyraldehyde Unclear - Unclear Arginine [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003936 KM-1406 SPD Oxidation - Oxidationn KM-1406 [4]
MR003934 AcSPM SPD Unclear KM-1406 [4]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003935 SPD AcSPD N1-acetylspermidine Unclear KM-1406 [4]
MR003071 Spermidine MTA Unclear Agmatine [2]
MR003070 Spermidine N1-AcSpd Unclear Agmatine [2]
MR003068 Spermidine Spermine Unclear Agmatine [2], [5], [6]
MR012736 Spermidine Spermine Unclear - Unclear Arginine [3]
References
1 Human aldehyde dehydrogenase: metabolism of putrescine and histamine
2 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.
3 Arginine Metabolism Revisited
4 Spermine metabolism and anticancer therapy
5 Genome-wide analysis of polyamine biosynthesis genes in wheat reveals gene expression specificity and involvement of STRE and MYB-elements in regulating polyamines under drought. BMC Genomics. 2022 Oct 30;23(1):734. doi: 10.1186/s12864-022-08946-2.
6 Unique Chemistry, Intake, and Metabolism of Polyamines in the Central Nervous System (CNS) and Its Body. Biomolecules. 2022 Mar 25;12(4):501. doi: 10.3390/biom12040501.

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