General Information of This Metabolic Reaction (MR) (ID: MR009199)
Formula
SVG example
Glycination
Reactant Benzoic acid Product Hippuric acid
Reactant Info Product Info
Metabolic Type Conjugation - Glycination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010983 Benzoic acid Salicylic acid Unclear - Unclear Benzoic acid [1]
MR004300 Benzoic acid Catechol Unclear Naphthoquinone [2]
MR003836 Benzoic acid 4-Hydroxyhippuric acid Unclear BE-14348A [3]
MR005289 Benzoic acid Benzoyl glucuronide Unclear Cinnamic acid [4]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010230 Isocarboxazid Hippuric acid Unclear - Unclear Isocarboxazid [5]
MR007547 Benzylamine M16 Benzylamine M1 Unclear Benzylamine [6]
MR004754 Midostaurin Metabolite P6 Midostaurin Metabolite P6B Unclear Midostaurin [7]
MR005014 4-Trifluoromethylphenol Hippuric acid Oxidation - O-dealkylation Fluoxetine hydrochloride [8]
MR006962 3-(Phenyl)propionic acid Hippuric acid Unclear CCG-208408 [9]
MR006885 Phenylacetone Hippuric acid Unclear Lisdexamfetamine [10]
MR005290 Cinnamic acid Metabolite Hippuric acid Unclear Cinnamic acid [4]
MR013577 4'-hydroxybenzoic acid Hippuric acid Unclear Epigallocatechin gallate [11]
⏷ Show the Full List of MR
References
1 Biosynthesis and metabolism of salicylic acid
2 Identification of naphthalene metabolism by white rot fungus Pleurotus eryngii
3 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
4 Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose
5 DrugBank(Pharmacology-Metabolism):Isocarboxazid
6 Bioactivation of benzylamine to reactive intermediates in rodents: formation of glutathione, glutamate, and peptide conjugates
7 Midostaurin, a novel protein kinase inhibitor for the treatment of acute myelogenous leukemia: insights from human absorption, metabolism, and excretion studies of a BDDCS II drug. Drug Metab Dispos. 2017 May;45(5):540-555.
8 DrugBank(Pharmacology-Metabolism):Fluoxetine hydrochloride
9 Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. Eur J Nutr. 2018 Feb;57(1):231-242.
10 Preclinical pharmacokinetics, pharmacology and toxicology of lisdexamfetamine: a novel d-amphetamine pro-drug. Neuropharmacology. 2014 Dec;87:41-50.
11 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate

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