Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005290)
Formula
SVG example
Reactant Cinnamic acid Metabolite Product Hippuric acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005287 Cinnamic acid Metabolite Cinnamic acid Metabolite Unclear Cinnamic acid [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005288 Cinnamic acid Metabolite Benzoic acid Unclear Cinnamic acid [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010230 Isocarboxazid Hippuric acid Unclear - Unclear Isocarboxazid [2]
MR007547 Benzylamine M16 Benzylamine M1 Unclear Benzylamine [3]
MR004754 Midostaurin Metabolite P6 Midostaurin Metabolite P6B Unclear Midostaurin [4]
MR005014 4-Trifluoromethylphenol Hippuric acid Oxidation - O-dealkylation Fluoxetine hydrochloride [5]
MR000219 Benzoic acid Hippuric acid Conjugation - Glycine Conjugation Amphetamine [6]
MR006962 3-(Phenyl)propionic acid Hippuric acid Unclear CCG-208408 [7]
MR003837 Benzoic acid Hippuric acid Unclear BE-14348A [8]
MR006885 Phenylacetone Hippuric acid Unclear Lisdexamfetamine [9]
MR009199 Benzoic acid Hippuric acid Conjugation - Glycination 3,4-Dihydroxycinnamic Acid [10]
MR013577 4'-hydroxybenzoic acid Hippuric acid Unclear Epigallocatechin gallate [11]
⏷ Show the Full List of MR
References
1 Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose
2 DrugBank(Pharmacology-Metabolism):Isocarboxazid
3 Bioactivation of benzylamine to reactive intermediates in rodents: formation of glutathione, glutamate, and peptide conjugates
4 Midostaurin, a novel protein kinase inhibitor for the treatment of acute myelogenous leukemia: insights from human absorption, metabolism, and excretion studies of a BDDCS II drug. Drug Metab Dispos. 2017 May;45(5):540-555.
5 DrugBank(Pharmacology-Metabolism):Fluoxetine hydrochloride
6 DrugBank(Pharmacology-Metabolism)Amphetamine
7 Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. Eur J Nutr. 2018 Feb;57(1):231-242.
8 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
9 Preclinical pharmacokinetics, pharmacology and toxicology of lisdexamfetamine: a novel d-amphetamine pro-drug. Neuropharmacology. 2014 Dec;87:41-50.
10 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
11 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate

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