Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011409)
Formula Reactant ITI-007 Product IC200565
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011408 ITI-007 IC200161 Oxidation - Dealkylation ITI-007 [1]
MR011407 ITI-007 ICI200131 Reduction - Reduction ITI-007 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010268 Lumateperone tosylate IC200565 Oxidation - N-desmethylation lumateperone tosylate [1]
References
1 An evaluation of lumateperone tosylate for the treatment of schizophrenia

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