Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01252)
Xenobiotics Name
Cinnamic acid
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
444539
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Steroid 17-alpha-monooxygenase (CYP17A1) DME Info Homo sapiens [1]
Cytochrome P450 2A6 (CYP2A6) DME Info Homo sapiens [1]
Mephenytoin 4-hydroxylase (CYP2C19) DME Info Homo sapiens [1]
Cytochrome P450 2C8 (CYP2C8) DME Info Homo sapiens [1]
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [1]
Cytochrome P450 2D6 (CYP2D6) DME Info Homo sapiens [1]
Cytochrome P450 2E1 (CYP2E1) DME Info Homo sapiens [1]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [1]
Beta-HSD adrenal and gonadal type (HSD3B2) DME Info Homo sapiens [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [2]
DME(s) Induced by This Xenobiotics
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [3]
References
1 Cinnamic acid based thiazolidinediones inhibit human P450c17 and 3beta-hydroxysteroid dehydrogenase and improve insulin sensitivity independent of PPARgamma agonist activity. J Mol Endocrinol. 2004 Apr;32(2):425-36.
2 Attenuation of Pseudomonas aeruginosa virulence by marine invertebrate-derived Streptomyces sp. Lett Appl Microbiol. 2013 Mar;56(3):197-207.
3 A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase. Nitric Oxide. 2005 Mar;12(2):97-104.

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