Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007824)
Formula
SVG example
Hydrolysis
Reactant Ipratropium Product Phenylacetic acid
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007823 Ipratropium N-isopropylnortropine-ester Hydrolysis - Hydrolysis Ipratropium [1]
MR007825 Ipratropium N-isopropylnortropium bromide Multi-steps Reaction - Demethylation; Hydrolysis Ipratropium [1]
MR007822 Ipratropium N-isopropylnortropium methobromide Reduction - Reduction Ipratropium [2], [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008132 Penicillin Phenylacetic acid Unclear - Unclear Penicillin [3]
MR008108 Penicillin G Sodium Phenyl acetic acid Hydrolysis - Hydrolysis Penicillin G Sodium [4]
MR002019 Phenelzine Phenylacetic acid Hydrolysis - Hydrolysis Phenelzine [5]
MR005608 Sodium phenylbutyrate Phenylacetic acid Oxidation - Oxidationn Sodium phenylbutyrate [6]
MR002015 Phenethylamine Phenylacetic acid Unclear Phenelzine [5]
MR009197 3-(phenyl)propanoic acid 3-(phenyl)acetic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [7]
MR004490 3'-Hydroxyphenylacetic acid Phenylacetic acid Unclear VS-12343 [8]
MR004498 3-(phenyl)propionic acid Phenylacetic acid Unclear VS-12343 [8]
⏷ Show the Full List of MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009198 3-(phenyl)acetic acid Benzoic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [7]
References
1 Ipratropium bromide: drug metabolism and pharmacokinetics
2 Ipratropium bromide HFA
3 Ligand-induced conformational change in penicillin acylase
4 A breakthrough in enzyme technology to fight penicillin resistance-industrial application of penicillin amidase
5 Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review J Psychiatry Neurosci. 1992 Nov;17(5):206-14.
6 DrugBank(Pharmacology-Metabolism):Sodium phenylbutyrate
7 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
8 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium

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