Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013582)
Formula
SVG example
Reactant 4'-hydroxyphenylacetic acid Product 3-methoxy-4'-hydroxyphenlacetic acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005864 L-tyrosine p-hydroxyphenylacetate Unclear L-tyrosine [1]
MR003838 3-(4-Hydroxyphenyl) propionic acid (4-Hydroxyphenyl) acetic acid Unclear BE-14348A [2]
MR002017 4- hydroxyphenelzine 4-hydroxyphenylacetic acid Hydrolysis - Hydrolysis Phenelzine [3]
MR002016 Phenylacetic acid 4-hydroxyphenylacetic acid Oxidation - 4-Hydroxylation Phenelzine [3]
MR013574 5-(3',4',5'-trihydroxyphenyl)valeric acid 4'-hydroxyphenylacetic acid Unclear Epigallocatechin gallate [4]
MR004501 3-(4'-Hydroxyphenyl)propionic acid 4'-Hydroxyphenylacetic acid Unclear VS-12343 [5]
MR004398 (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid 2-(4-Hydroxyphenyl)acetic acid Unclear N-nonylphenol [6]
MR004404 2-(4-Hydroxyphenyl)acetic acid 2-(4-Hydroxyphenyl)acetic acid Unclear N-nonylphenol [6]
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Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013575 4'-hydroxyphenylacetic acid 3',4'-dihydroxyphenylacetic acid Unclear Epigallocatechin gallate [4]
MR013576 4'-hydroxyphenylacetic acid 4'-hydroxybenzoic acid Unclear Epigallocatechin gallate [4]
MR004502 4'-Hydroxyphenylacetic acid 4-Hydroxybenzoic acid Unclear VS-12343 [5]
MR004403 2-(4-Hydroxyphenyl)acetic acid (3,4-Dihydroxyphenyl)acetic acid Oxidation - Hydrolyzationn N-nonylphenol [6]
MR004399 2-(4-Hydroxyphenyl)acetic acid 1-(4-hydroxyphenyl)ethanone Unclear N-nonylphenol [6]
MR004404 2-(4-Hydroxyphenyl)acetic acid 2-(4-Hydroxyphenyl)acetic acid Unclear N-nonylphenol [6]
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Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010921 Isovanillin Vanillic acid Unclear - Unclear Isovanillin [7]
MR013911 Veratric acid Vanillic acid Oxidation - O-demethylation Mebeverine [8]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010924 Vanillic acid Anilloylglycine Unclear - Unclear Isovanillin [7]
MR010923 Vanillic acid Guaiacol Unclear - Unclear Isovanillin [7]
MR010922 Vanillic acid Protocatechuic acid Unclear - Unclear Isovanillin [7]
MR013912 Vanillic acid Mebeverine Metabolite M2 Unclear - Unclear Mebeverine [8]
References
1 Potent inhibitory effects of tyrosine metabolites on dihydropteridine reductase from human and sheep liver
2 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
3 Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review J Psychiatry Neurosci. 1992 Nov;17(5):206-14.
4 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
5 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
6 4-n-nonylphenol degradation by the genus Metarhizium with cytochrome P450 involvement
7 The metabolism of vanillin and isovanillin in the rat
8 Investigative implications of the instability and metabolism of mebeverine

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