Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO04332)
Xenobiotics Name
Nosiheptide
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Streptococcus pyogenes [1], [2]
Dihydrofolate reductase (folA) DME Info Escherichia coli [1], [2]
Dihydrofolate reductase (folA) DME Info Lactobacillus casei [1], [2]
Folylpolyglutamate synthetase (fpgS) DME Info Lactobacillus casei [1], [2]
Inositol dehydrogenase (idh) DME Info Lactobacillus casei [1], [2]
Inositol dehydrogenase (idh) DME Info Lactobacillus casei [1], [2]
L-Lactate dehydrogenase (ldh) DME Info Lactobacillus casei [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Pyruvate oxidase (pyrO) DME Info Lactobacillus casei [1], [2]
Thymidylate synthase (thyA) DME Info Lactobacillus casei [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 0.00028 ug/ml [1], [2]
Dihydrofolate reductase (folA) DME Info MIC = 0.003 ug/ml [1], [2]
Dihydrofolate reductase (folA) DME Info MIC = 0.003 ug/ml [1], [2]
Folylpolyglutamate synthetase (fpgS) DME Info MIC = 0.003 ug/ml [1], [2]
Inositol dehydrogenase (idh) DME Info MIC = 0.003 ug/ml [1], [2]
Inositol dehydrogenase (idh) DME Info MIC = 0.003 ug/ml [1], [2]
L-Lactate dehydrogenase (ldh) DME Info MIC = 0.003 ug/ml [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 0.0009 ug/ml [1], [2]
Pyruvate oxidase (pyrO) DME Info MIC = 0.003 ug/ml [1], [2]
Thymidylate synthase (thyA) DME Info MIC = 0.003 ug/ml [1], [2]
References
1 Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework. ACS Chem Biol. 2009 Oct 16;4(10):855-64.
2 Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol Cell. 2008 Apr 11;30(1):26-38.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.