Details of Microbiome-DME Interaction (MICBIO)

General Information of Drug-Metabolizing Enzyme (DME ID: DME0015)
DME Name	Cytochrome P450 3A7 (CYP3A7), Homo sapiens	DME Info
UniProt ID	CP3A7_HUMAN
EC Number	EC: 1.14.14.1 (Click to Show/Hide the Complete EC Tree) Oxidoreductase Oxygen paired donor oxidoreductase Flavin/flavoprotein donor oxidoreductase EC: 1.14.14.1
Lineage	Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage) Kingdom: Metazoa Phylum: Chordata Class: Mammalia Order: Primates Family: Hominidae Genus: Homo Species: Homo sapiens
Interactome

Interactions between Microbiome and DME (MICBIO)
Bacteria: Actinobacteria
Bifidobacterium adolescentis (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bifidobacterium adolescentis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Bifidobacterium longum (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bifidobacterium longum co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Bifidobacterium ruminatum (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bifidobacterium ruminatum co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Collinsella intestinalis (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Collinsella intestinalis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Eggerthella lenta (actinobacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Eggerthella lenta co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Paclitaxel		Click to Show/Hide the Detail
Drug ID	DR1227 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Eggerthella lenta co-metabolize the drug Paclitaxel, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Mycobacterium tuberculosis (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Dextromethorphan hydrobromide		Click to Show/Hide the Detail
Drug ID	DR0476 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Mycobacterium tuberculosis co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug.		[2], [3]
Streptomyces avermitilis (actinobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Testosterone cypionate		Click to Show/Hide the Detail
Drug ID	DR1564 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Streptomyces avermitilis co-metabolize the drug Testosterone cypionate, which can collectively affect efficacy, safety or bioavailability of this drug.		[4], [5], [6]
Bacteria: Bacteroidetes
Alistipes indistinctus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 4 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Alistipes indistinctus co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Cyclophosphamide		Click to Show/Hide the Detail
Drug ID	DR0391 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Alistipes indistinctus co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Alistipes indistinctus co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Alistipes indistinctus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides caccae (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides caccae co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides caccae co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides cellulosilyticus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides cellulosilyticus co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides cellulosilyticus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides coprophilus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides coprophilus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides dorei (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 8 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides dorei co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Dexamethasone acetate		Click to Show/Hide the Detail
Drug ID	DR0451 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides dorei co-metabolize the drug Dexamethasone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[10], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides dorei co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Finasteride		Click to Show/Hide the Detail
Drug ID	DR0695 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides dorei co-metabolize the drug Finasteride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides dorei co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides dorei co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[11], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides dorei co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Zaleplon		Click to Show/Hide the Detail
Drug ID	DR1725 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides dorei co-metabolize the drug Zaleplon, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Bacteroides eggerthii (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 4 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides eggerthii co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides eggerthii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides eggerthii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides eggerthii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Bacteroides finegoldii (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides finegoldii co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides finegoldii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides fragilis (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 10 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Cyclophosphamide		Click to Show/Hide the Detail
Drug ID	DR0391 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [1]
Dexamethasone acetate		Click to Show/Hide the Detail
Drug ID	DR0451 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Dexamethasone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[10], [1]
Finasteride		Click to Show/Hide the Detail
Drug ID	DR0695 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Finasteride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [14], [15]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Paclitaxel		Click to Show/Hide the Detail
Drug ID	DR1227 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Paclitaxel, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Zaleplon		Click to Show/Hide the Detail
Drug ID	DR1725 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides fragilis co-metabolize the drug Zaleplon, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Bacteroides intestinalis (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides intestinalis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides intestinalis co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides ovatus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides ovatus co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides ovatus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides sartorii (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 10 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Dexamethasone acetate		Click to Show/Hide the Detail
Drug ID	DR0451 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Dexamethasone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[10], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Finasteride		Click to Show/Hide the Detail
Drug ID	DR0695 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Finasteride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Paclitaxel		Click to Show/Hide the Detail
Drug ID	DR1227 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Paclitaxel, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[11], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Zaleplon		Click to Show/Hide the Detail
Drug ID	DR1725 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides sartorii co-metabolize the drug Zaleplon, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Bacteroides stercoris (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides stercoris co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Dexamethasone acetate		Click to Show/Hide the Detail
Drug ID	DR0451 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides stercoris co-metabolize the drug Dexamethasone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[10], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides stercoris co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides thetaiotaomicron (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 8 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides thetaiotaomicron co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Dexamethasone acetate		Click to Show/Hide the Detail
Drug ID	DR0451 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides thetaiotaomicron co-metabolize the drug Dexamethasone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[10], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides thetaiotaomicron co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) metabolizes the drug Irinotecan hydrochloride, and Bacteroides thetaiotaomicron further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[], [16]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides thetaiotaomicron co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides thetaiotaomicron co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Paclitaxel		Click to Show/Hide the Detail
Drug ID	DR1227 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides thetaiotaomicron co-metabolize the drug Paclitaxel, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides thetaiotaomicron co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Bacteroides uniformis (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides uniformis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) metabolizes the drug Irinotecan hydrochloride, and Bacteroides uniformis further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[], [16]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides uniformis co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteroides vulgatus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 9 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Finasteride		Click to Show/Hide the Detail
Drug ID	DR0695 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug Finasteride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Imatinib mesylate		Click to Show/Hide the Detail
Drug ID	DR0858 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug Imatinib mesylate, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[11], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Verapamil hydrochloride		Click to Show/Hide the Detail
Drug ID	DR1681 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug Verapamil hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[17], [1]
Zaleplon		Click to Show/Hide the Detail
Drug ID	DR1725 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides vulgatus co-metabolize the drug Zaleplon, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Bacteroides xylanisolvens (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 10 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Dexamethasone acetate		Click to Show/Hide the Detail
Drug ID	DR0451 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Dexamethasone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[10], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Finasteride		Click to Show/Hide the Detail
Drug ID	DR0695 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Finasteride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Paclitaxel		Click to Show/Hide the Detail
Drug ID	DR1227 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Paclitaxel, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[11], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Zaleplon		Click to Show/Hide the Detail
Drug ID	DR1725 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacteroides xylanisolvens co-metabolize the drug Zaleplon, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Odoribacter splanchnicus (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 6 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Odoribacter splanchnicus co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Finasteride		Click to Show/Hide the Detail
Drug ID	DR0695 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Odoribacter splanchnicus co-metabolize the drug Finasteride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Odoribacter splanchnicus co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Odoribacter splanchnicus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Paclitaxel		Click to Show/Hide the Detail
Drug ID	DR1227 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Odoribacter splanchnicus co-metabolize the drug Paclitaxel, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Odoribacter splanchnicus co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Parabacteroides distasonis (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 6 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides distasonis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides distasonis co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Finasteride		Click to Show/Hide the Detail
Drug ID	DR0695 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides distasonis co-metabolize the drug Finasteride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides distasonis co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Phenytoin		Click to Show/Hide the Detail
Drug ID	DR1282 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides distasonis co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug.		[11], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides distasonis co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Parabacteroides johnsonii (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides johnsonii co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides johnsonii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides johnsonii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Parabacteroides merdae (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides merdae co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides merdae co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Parabacteroides merdae co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Prevotella copri (CFB bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Prevotella copri co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Prevotella copri co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Bacteria: Firmicutes
Anaerobutyricum hallii (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Anaerobutyricum hallii co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Anaerococcus hydrogenalis (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Anaerococcus hydrogenalis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Anaerostipes hadrus (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Anaerostipes hadrus co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Imatinib mesylate		Click to Show/Hide the Detail
Drug ID	DR0858 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Anaerostipes hadrus co-metabolize the drug Imatinib mesylate, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Anaerotruncus colihominis (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Anaerotruncus colihominis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Pimozide		Click to Show/Hide the Detail
Drug ID	DR1291 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Anaerotruncus colihominis co-metabolize the drug Pimozide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Bacillus megaterium (firmicutes)		Click to Show/Hide the Full List of Drugs: 5 Drugs Metabolized
Buspirone		Click to Show/Hide the Detail
Drug ID	DR0248 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacillus megaterium co-metabolize the drug Buspirone, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [18], [19]
Dextromethorphan hydrobromide		Click to Show/Hide the Detail
Drug ID	DR0476 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacillus megaterium co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug.		[2], [18]
Progesterone		Click to Show/Hide the Detail
Drug ID	DR1346 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacillus megaterium co-metabolize the drug Progesterone, which can collectively affect efficacy, safety or bioavailability of this drug.		[20], [19]
Propranolol hydrochloride		Click to Show/Hide the Detail
Drug ID	DR1367 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacillus megaterium co-metabolize the drug Propranolol hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[21], [19]
Testosterone cypionate		Click to Show/Hide the Detail
Drug ID	DR1564 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Bacillus megaterium co-metabolize the drug Testosterone cypionate, which can collectively affect efficacy, safety or bioavailability of this drug.		[4], [19], [22]
Blautia hansenii (firmicutes)		Click to Show/Hide the Full List of Drugs: 9 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Cyclophosphamide		Click to Show/Hide the Detail
Drug ID	DR0391 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nevirapine		Click to Show/Hide the Detail
Drug ID	DR1142 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug Nevirapine, which can collectively affect efficacy, safety or bioavailability of this drug.		[23], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Sildenafil citrate		Click to Show/Hide the Detail
Drug ID	DR1481 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Zaleplon		Click to Show/Hide the Detail
Drug ID	DR1725 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia hansenii co-metabolize the drug Zaleplon, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Blautia luti (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Blautia luti co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Clostridioides difficile (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridioides difficile co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Sildenafil citrate		Click to Show/Hide the Detail
Drug ID	DR1481 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridioides difficile co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Clostridium botulinum (firmicutes)		Click to Show/Hide the Full List of Drugs: 9 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Nateglinide		Click to Show/Hide the Detail
Drug ID	DR1132 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Nevirapine		Click to Show/Hide the Detail
Drug ID	DR1142 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug Nevirapine, which can collectively affect efficacy, safety or bioavailability of this drug.		[23], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Pimozide		Click to Show/Hide the Detail
Drug ID	DR1291 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug Pimozide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Sildenafil citrate		Click to Show/Hide the Detail
Drug ID	DR1481 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Zaleplon		Click to Show/Hide the Detail
Drug ID	DR1725 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium botulinum co-metabolize the drug Zaleplon, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Clostridium leptum (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
RO-7-0207		Click to Show/Hide the Detail
Drug ID	DR1204 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium leptum co-metabolize the drug RO-7-0207, which can collectively affect efficacy, safety or bioavailability of this drug.		[24], [25]
Clostridium perfringens (firmicutes)		Click to Show/Hide the Full List of Drugs: 4 Drugs Metabolized
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) metabolizes the drug Irinotecan hydrochloride, and Clostridium perfringens further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[], [26]
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium perfringens co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [27]
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium perfringens co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [27]
RO-7-0207		Click to Show/Hide the Detail
Drug ID	DR1204 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium perfringens co-metabolize the drug RO-7-0207, which can collectively affect efficacy, safety or bioavailability of this drug.		[24], [25]
Clostridium scindens (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium scindens co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Dexamethasone acetate		Click to Show/Hide the Detail
Drug ID	DR0451 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium scindens co-metabolize the drug Dexamethasone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[10], [1]
Clostridium spiroforme (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium spiroforme co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Clostridium sporogenes (firmicutes)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium sporogenes co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
RO-7-0207		Click to Show/Hide the Detail
Drug ID	DR1204 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium sporogenes co-metabolize the drug RO-7-0207, which can collectively affect efficacy, safety or bioavailability of this drug.		[24], [25]
Zonisamide		Click to Show/Hide the Detail
Drug ID	DR1737 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium sporogenes co-metabolize the drug Zonisamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[28], [29]
Clostridium symbiosum (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Clostridium symbiosum co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Coprococcus comes (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Coprococcus comes co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Dorea formicigenerans (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Dorea formicigenerans co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Enterocloster asparagiformis (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Enterocloster asparagiformis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Enterocloster bolteae (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Enterocloster bolteae co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Pimozide		Click to Show/Hide the Detail
Drug ID	DR1291 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Enterocloster bolteae co-metabolize the drug Pimozide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Enterococcus casseliflavus (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Enterococcus casseliflavus co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [30]
Enterococcus gallinarum (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Enterococcus gallinarum co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [30]
Erysipelatoclostridium ramosum (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Erysipelatoclostridium ramosum co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Eubacterium cellulosolvens (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0077922		Click to Show/Hide the Detail
Drug ID	DR0786 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Eubacterium cellulosolvens co-metabolize the drug BRN-0077922, which can collectively affect efficacy, safety or bioavailability of this drug.		[31], [32]
Eubacterium oxidoreducens (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
RO-7-0207		Click to Show/Hide the Detail
Drug ID	DR1204 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Eubacterium oxidoreducens co-metabolize the drug RO-7-0207, which can collectively affect efficacy, safety or bioavailability of this drug.		[24], [25]
Eubacterium rectale (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Eubacterium rectale co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Eubacterium ventriosum (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Eubacterium ventriosum co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Holdemanella biformis (firmicutes)		Click to Show/Hide the Full List of Drugs: 3 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Holdemanella biformis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Cyclophosphamide		Click to Show/Hide the Detail
Drug ID	DR0391 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Holdemanella biformis co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug.		[7], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Holdemanella biformis co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Hungatella hathewayi (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Hungatella hathewayi co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Hungatella hathewayi co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Lactobacillus sakei (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Erythromycin stearate		Click to Show/Hide the Detail
Drug ID	DR0614 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Lactobacillus sakei co-metabolize the drug Erythromycin stearate, which can collectively affect efficacy, safety or bioavailability of this drug.		[23], [33], [34]
Marvinbryantia formatexigens (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Marvinbryantia formatexigens co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Mediterraneibacter glycyrrhizinilyticus (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0077922		Click to Show/Hide the Detail
Drug ID	DR0786 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Mediterraneibacter glycyrrhizinilyticus co-metabolize the drug BRN-0077922, which can collectively affect efficacy, safety or bioavailability of this drug.		[31], [35]
Roseburia intestinalis (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Roseburia intestinalis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Ruminococcus gnavus (firmicutes)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Ruminococcus gnavus co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Ruminococcus gnavus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Ruminococcus lactaris (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Ruminococcus lactaris co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Ruminococcus torques (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Ruminococcus torques co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Streptococcus agalactiae (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) metabolizes the drug Irinotecan hydrochloride, and Streptococcus agalactiae further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[], [26]
Subdoligranulum variabile (firmicutes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Subdoligranulum variabile co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Bacteria: Lentisphaerae
Victivallis vadensis (PVC bacteria)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
BRN-0498823		Click to Show/Hide the Detail
Drug ID	DR1167 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Victivallis vadensis co-metabolize the drug BRN-0498823, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Diltiazem hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0509 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Victivallis vadensis co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[8], [1]
Bacteria: Proteobacteria
Enterobacter cloacae (enterobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Enterobacter cloacae co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [36]
Escherichia coli (enterobacteria)		Click to Show/Hide the Full List of Drugs: 5 Drugs Metabolized
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) metabolizes the drug Irinotecan hydrochloride, and Escherichia coli further metabolizes its metabolite (SN-38G), which can indirectly affect efficacy, safety or bioavailability of this drug.		[], [37]
Irinotecan hydrochloride		Click to Show/Hide the Detail
Drug ID	DR0881 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Escherichia coli co-metabolize the drug Irinotecan hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [37]
Norethindrone acetate		Click to Show/Hide the Detail
Drug ID	DR1750 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Escherichia coli co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug.		[9], [1]
Paclitaxel		Click to Show/Hide the Detail
Drug ID	DR1227 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Escherichia coli co-metabolize the drug Paclitaxel, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Ritonavir		Click to Show/Hide the Detail
Drug ID	DR1430 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Escherichia coli co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug.		[12], [1]
Klebsiella pneumoniae (enterobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Aztreonam		Click to Show/Hide the Detail
Drug ID	DR0169 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Klebsiella pneumoniae co-metabolize the drug Aztreonam, which can collectively affect efficacy, safety or bioavailability of this drug.		[38], [39]
Klebsiella variicola (enterobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Aztreonam		Click to Show/Hide the Detail
Drug ID	DR0169 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Klebsiella variicola co-metabolize the drug Aztreonam, which can collectively affect efficacy, safety or bioavailability of this drug.		[38], [40]
Salmonella enterica (enterobacteria)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
RO-7-0207		Click to Show/Hide the Detail
Drug ID	DR1204 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Salmonella enterica co-metabolize the drug RO-7-0207, which can collectively affect efficacy, safety or bioavailability of this drug.		[24], [41]
Bacteria: Verrucomicrobia
Akkermansia muciniphila (verrucomicrobiae)		Click to Show/Hide the Full List of Drugs: 2 Drugs Metabolized
Finasteride		Click to Show/Hide the Detail
Drug ID	DR0695 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Akkermansia muciniphila co-metabolize the drug Finasteride, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Pimozide		Click to Show/Hide the Detail
Drug ID	DR1291 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Akkermansia muciniphila co-metabolize the drug Pimozide, which can collectively affect efficacy, safety or bioavailability of this drug.		[], [1]
Amoebozoa: Evosea
Entamoeba histolytica (eukaryotes)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Entamoeba histolytica co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [42]
Metamonada: Fornicata
Giardia intestinalis (diplomonads)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Giardia intestinalis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [42]
Metamonada: Parabasalia
Trichomonas vaginalis (trichomonads)		Click to Show/Hide the Full List of Drugs: 1 Drugs Metabolized
Metronidazole		Click to Show/Hide the Detail
Drug ID	DR1073 Drug Info
Interaction Mechanism	Human Cytochrome P450 3A7 (CYP3A7) and Trichomonas vaginalis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug.		[13], [42]

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