Details of Microbiome-DME Interaction (MICBIO)

General Information of Drug-Metabolizing Enzyme (DME ID: DME0021)
DME Name Mephenytoin 4-hydroxylase (CYP2C19), Homo sapiens DME Info
UniProt ID
CP2CJ_HUMAN
EC Number    EC: 1.14.14.1     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
Oxygen paired donor oxidoreductase
Flavin/flavoprotein donor oxidoreductase
EC: 1.14.14.1
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Interactome
Interactions between Microbiome and DME (MICBIO)
      Bacteria: Actinobacteria
                  Bifidobacterium adolescentis (actinobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium adolescentis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium adolescentis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium adolescentis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium adolescentis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bifidobacterium breve (actinobacteria) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium breve co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium breve co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium breve co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium breve co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium breve co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium breve co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Bifidobacterium longum (actinobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium longum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium longum co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [8]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium longum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium longum co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bifidobacterium ruminatum (actinobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium ruminatum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium ruminatum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium ruminatum co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bifidobacterium ruminatum co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Collinsella aerofaciens (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Zidovudine Click to Show/Hide the Detail
                                 Drug ID DR1729   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Collinsella aerofaciens co-metabolize the drug Zidovudine, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Collinsella intestinalis (actinobacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Collinsella intestinalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Collinsella intestinalis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Collinsella intestinalis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Eggerthella lenta (actinobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Dopamine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0532   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eggerthella lenta co-metabolize the drug Dopamine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [12]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eggerthella lenta co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eggerthella lenta co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eggerthella lenta co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Mycobacterium tuberculosis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Dextromethorphan hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0476   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Mycobacterium tuberculosis co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [14]
                  Nocardia farcinica (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Nocardia farcinica co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [16]
                  Streptomyces avermitilis (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Streptomyces avermitilis co-metabolize the drug Diclofenac sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [18], [19]
                              Testosterone cypionate Click to Show/Hide the Detail
                                 Drug ID DR1564   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Streptomyces avermitilis co-metabolize the drug Testosterone cypionate, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [21], [18]
      Bacteria: Bacteroidetes
                  Alistipes indistinctus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Cyclophosphamide Click to Show/Hide the Detail
                                 Drug ID DR0391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Alistipes indistinctus co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Alistipes indistinctus co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Alistipes indistinctus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Alistipes indistinctus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Alistipes indistinctus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Alistipes indistinctus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Alistipes indistinctus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Alloprevotella tannerae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Alloprevotella tannerae co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [26]
                  Bacteroides caccae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides caccae co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides caccae co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides caccae co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Bacteroides cellulosilyticus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides cellulosilyticus co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides cellulosilyticus co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides cellulosilyticus co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides cellulosilyticus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides cellulosilyticus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides cellulosilyticus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides cellulosilyticus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides cellulosilyticus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Bacteroides coprophilus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides coprophilus co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides coprophilus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides coprophilus co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides coprophilus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides coprophilus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides coprophilus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides coprophilus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides coprophilus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Bacteroides dorei (CFB bacteria) Click to Show/Hide the Full List of Drugs:      20 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Diclofenac sodium, and Bacteroides dorei further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [31]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Methsuximide Click to Show/Hide the Detail
                                 Drug ID DR1050   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Methsuximide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides dorei co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Bacteroides eggerthii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides eggerthii co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [37]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides eggerthii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides eggerthii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides eggerthii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides eggerthii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides eggerthii co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides eggerthii co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides eggerthii co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Bacteroides finegoldii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides finegoldii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides finegoldii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides finegoldii co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bacteroides fragilis (CFB bacteria) Click to Show/Hide the Full List of Drugs:      19 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Cyclophosphamide Click to Show/Hide the Detail
                                 Drug ID DR0391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Lofexidine Click to Show/Hide the Detail
                                 Drug ID DR0967   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Lofexidine, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naftopidil Click to Show/Hide the Detail
                                 Drug ID DR1124   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Naftopidil, which can collectively affect efficacy, safety or bioavailability of this drug. [39], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Warfarin sodium Click to Show/Hide the Detail
                                 Drug ID DR1717   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides fragilis co-metabolize the drug Warfarin sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [40], [2]
                  Bacteroides intestinalis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides intestinalis co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides intestinalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides intestinalis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides intestinalis co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides intestinalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides intestinalis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides intestinalis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides intestinalis co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Bacteroides oleiciplenus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides oleiciplenus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [41]
                  Bacteroides ovatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides ovatus co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides ovatus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides ovatus co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides ovatus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides ovatus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides ovatus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides ovatus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides ovatus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Bacteroides sartorii (CFB bacteria) Click to Show/Hide the Full List of Drugs:      14 Drugs Metabolized
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides sartorii co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Bacteroides stercoris (CFB bacteria) Click to Show/Hide the Full List of Drugs:      11 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides stercoris co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Bacteroides thetaiotaomicron (CFB bacteria) Click to Show/Hide the Full List of Drugs:      14 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [8]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides thetaiotaomicron co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Bacteroides uniformis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides uniformis co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides uniformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides uniformis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides uniformis co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides uniformis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides uniformis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides uniformis co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Bacteroides vulgatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:      18 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [27], [42]
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Indomethacin, and Bacteroides vulgatus further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [4], [43]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                              Verapamil hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1681   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Verapamil hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [44], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Warfarin sodium Click to Show/Hide the Detail
                                 Drug ID DR1717   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides vulgatus co-metabolize the drug Warfarin sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [40], [2]
                  Bacteroides xylanisolvens (CFB bacteria) Click to Show/Hide the Full List of Drugs:      13 Drugs Metabolized
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides xylanisolvens co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Capnocytophaga gingivalis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Capnocytophaga gingivalis co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [45]
                  Capnocytophaga granulosa (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Capnocytophaga granulosa co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [45]
                  Capnocytophaga haemolytica (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Capnocytophaga haemolytica co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46]
                  Capnocytophaga leadbetteri (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Capnocytophaga leadbetteri co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [45]
                  Capnocytophaga ochracea (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Capnocytophaga ochracea co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [45]
                  Capnocytophaga sputigena (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Capnocytophaga sputigena co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [45]
                  Odoribacter splanchnicus (CFB bacteria) Click to Show/Hide the Full List of Drugs:      14 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [47], [48]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Odoribacter splanchnicus co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Parabacteroides distasonis (CFB bacteria) Click to Show/Hide the Full List of Drugs:      12 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [49]
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides distasonis co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Parabacteroides johnsonii (CFB bacteria) Click to Show/Hide the Full List of Drugs:      10 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides johnsonii co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Parabacteroides merdae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        9 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Parabacteroides merdae co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Prevotella bivia (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella bivia co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [47], [48]
                  Prevotella buccae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella buccae co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46]
                  Prevotella copri (CFB bacteria) Click to Show/Hide the Full List of Drugs:      11 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [50]
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [51], [52]
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella copri co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Prevotella denticola (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella denticola co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46]
                  Prevotella intermedia (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella intermedia co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [26]
                  Prevotella loescheii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella loescheii co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46]
                  Prevotella melaninogenica (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella melaninogenica co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46], [53]
                  Prevotella nigrescens (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella nigrescens co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [26], [46]
                  Prevotella oralis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella oralis co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [47], [48]
                  Prevotella veroralis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Prevotella veroralis co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46]
      Bacteria: Firmicutes
                  Acidaminococcus fermentans (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Acidaminococcus fermentans co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [54]
                  Acidaminococcus intestini (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Acidaminococcus intestini co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [55]
                  Anaerobutyricum hallii (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerobutyricum hallii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerobutyricum hallii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerobutyricum hallii co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerobutyricum hallii co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Anaerococcus hydrogenalis (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerococcus hydrogenalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerococcus hydrogenalis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerococcus hydrogenalis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Zidovudine Click to Show/Hide the Detail
                                 Drug ID DR1729   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerococcus hydrogenalis co-metabolize the drug Zidovudine, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Anaerostipes hadrus (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerostipes hadrus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerostipes hadrus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Anaerotruncus colihominis (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerotruncus colihominis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerotruncus colihominis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Anaerotruncus colihominis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Bacillus megaterium (firmicutes) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Dextromethorphan hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0476   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacillus megaterium co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [56]
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacillus megaterium co-metabolize the drug Diclofenac sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [57]
                              Progesterone Click to Show/Hide the Detail
                                 Drug ID DR1346   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacillus megaterium co-metabolize the drug Progesterone, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [58]
                              Propranolol hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1367   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacillus megaterium co-metabolize the drug Propranolol hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [59], [58]
                              Testosterone cypionate Click to Show/Hide the Detail
                                 Drug ID DR1564   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacillus megaterium co-metabolize the drug Testosterone cypionate, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [58], [60]
                  Bacillus pumilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Chloramphenicol Click to Show/Hide the Detail
                                 Drug ID DR0298   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacillus pumilus co-metabolize the drug Chloramphenicol, which can collectively affect efficacy, safety or bioavailability of this drug. [61], [62]
                  Bacteroides pectinophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides pectinophilus co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides pectinophilus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides pectinophilus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides pectinophilus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Bacteroides pectinophilus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Blautia hansenii (firmicutes) Click to Show/Hide the Full List of Drugs:      12 Drugs Metabolized
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Cyclophosphamide Click to Show/Hide the Detail
                                 Drug ID DR0391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ramelteon Click to Show/Hide the Detail
                                 Drug ID DR1391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Ramelteon, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [63], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia hansenii co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Blautia luti (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia luti co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Blautia luti co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Clostridioides difficile (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridioides difficile co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridioides difficile co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridioides difficile co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridioides difficile co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [63], [2]
                  Clostridium botulinum (firmicutes) Click to Show/Hide the Full List of Drugs:      13 Drugs Metabolized
                              Carisoprodol Click to Show/Hide the Detail
                                 Drug ID DR0277   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Carisoprodol, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Methsuximide Click to Show/Hide the Detail
                                 Drug ID DR1050   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Methsuximide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Paroxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1245   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Paroxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [64], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [63], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium botulinum co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Clostridium perfringens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium perfringens co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [8]
                  Clostridium scindens (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium scindens co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium scindens co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium scindens co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Clostridium spiroforme (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium spiroforme co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium spiroforme co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium spiroforme co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium spiroforme co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Clostridium sporogenes (firmicutes) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium sporogenes co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium sporogenes co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium sporogenes co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium sporogenes co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium sporogenes co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Zonisamide Click to Show/Hide the Detail
                                 Drug ID DR1737   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium sporogenes co-metabolize the drug Zonisamide, which can collectively affect efficacy, safety or bioavailability of this drug. [65], [66]
                  Clostridium symbiosum (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium symbiosum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium symbiosum co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Clostridium symbiosum co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Coprococcus comes (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Coprococcus comes co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Coprococcus comes co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Coprococcus comes co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Dorea formicigenerans (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Dorea formicigenerans co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Dorea formicigenerans co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Dorea formicigenerans co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Dorea formicigenerans co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Enterocloster asparagiformis (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterocloster asparagiformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterocloster asparagiformis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterocloster asparagiformis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterocloster asparagiformis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Enterocloster bolteae (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterocloster bolteae co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterocloster bolteae co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterocloster bolteae co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterocloster bolteae co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Enterococcus faecalis (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterococcus faecalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterococcus faecalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterococcus faecalis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterococcus faecalis co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                  Erysipelatoclostridium ramosum (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Erysipelatoclostridium ramosum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Indomethacin, and Erysipelatoclostridium ramosum further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [4], [43]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Erysipelatoclostridium ramosum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Erysipelatoclostridium ramosum co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Erysipelothrix rhusiopathiae (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Chloramphenicol Click to Show/Hide the Detail
                                 Drug ID DR0298   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Erysipelothrix rhusiopathiae co-metabolize the drug Chloramphenicol, which can collectively affect efficacy, safety or bioavailability of this drug. [61], [67], [68]
                  Eubacterium limosum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eubacterium limosum co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [8]
                  Eubacterium rectale (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eubacterium rectale co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eubacterium rectale co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eubacterium rectale co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Eubacterium ventriosum (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eubacterium ventriosum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eubacterium ventriosum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eubacterium ventriosum co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Eubacterium ventriosum co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Faecalibacterium prausnitzii (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Diclofenac sodium, and Faecalibacterium prausnitzii further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [31]
                  Holdemanella biformis (firmicutes) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Cyclophosphamide Click to Show/Hide the Detail
                                 Drug ID DR0391   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Holdemanella biformis co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Holdemanella biformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Holdemanella biformis co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Holdemanella biformis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Holdemanella biformis co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Holdemanella biformis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Holdemanella biformis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Hungatella hathewayi (firmicutes) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Hungatella hathewayi co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Hungatella hathewayi co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Hungatella hathewayi co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Hungatella hathewayi co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Hungatella hathewayi co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Jeotgalicoccus psychrophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Jeotgalicoccus psychrophilus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [51], [52]
                  Lactobacillus reuteri (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Lactobacillus reuteri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Lactobacillus reuteri co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Lactobacillus reuteri co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Lactobacillus rhamnosus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Diclofenac sodium, and Lactobacillus rhamnosus further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [31]
                  Marvinbryantia formatexigens (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Marvinbryantia formatexigens co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Marvinbryantia formatexigens co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Peptostreptococcus anaerobius (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Peptostreptococcus anaerobius co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46]
                  Pseudoflavonifractor capillosus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Pseudoflavonifractor capillosus co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [69]
                  Roseburia hominis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Indomethacin, and Roseburia hominis further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [4], [43]
                  Roseburia intestinalis (firmicutes) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Roseburia intestinalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Indomethacin, and Roseburia intestinalis further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [4], [43]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Roseburia intestinalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Roseburia intestinalis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Roseburia intestinalis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Ruminococcus albus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus albus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [51], [52]
                  Ruminococcus gnavus (firmicutes) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Diclofenac sodium, and Ruminococcus gnavus further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [31]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus gnavus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus gnavus co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus gnavus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus gnavus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus gnavus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Ruminococcus lactaris (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus lactaris co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus lactaris co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus lactaris co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus lactaris co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Ruminococcus torques (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus torques co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus torques co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Ruminococcus torques co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Subdoligranulum variabile (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Subdoligranulum variabile co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Subdoligranulum variabile co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Subdoligranulum variabile co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
      Bacteria: Fusobacteria
                  Fusobacterium mortiferum (fusobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Fusobacterium mortiferum co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [47], [48]
                  Fusobacterium varium (fusobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Fusobacterium varium co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [47]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Fusobacterium varium co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [8]
      Bacteria: Lentisphaerae
                  Victivallis vadensis (PVC bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Victivallis vadensis co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Victivallis vadensis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Victivallis vadensis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Victivallis vadensis co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
      Bacteria: Proteobacteria
                  Achromobacter xylosoxidans (beta-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Achromobacter xylosoxidans co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [70]
                  Acidovorax ebreus (beta-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Acidovorax ebreus co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [71]
                  Citrobacter freundii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Citrobacter freundii co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46]
                  Edwardsiella tarda (enterobacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Edwardsiella tarda co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Edwardsiella tarda co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Edwardsiella tarda co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Enterobacter cancerogenus (enterobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterobacter cancerogenus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterobacter cancerogenus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterobacter cancerogenus co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Enterobacter cancerogenus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Escherichia coli (enterobacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Chloramphenicol Click to Show/Hide the Detail
                                 Drug ID DR0298   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Escherichia coli co-metabolize the drug Chloramphenicol, which can collectively affect efficacy, safety or bioavailability of this drug. [61], [62]
                              Flunitrazepam Click to Show/Hide the Detail
                                 Drug ID DR0712   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Escherichia coli co-metabolize the drug Flunitrazepam, which can collectively affect efficacy, safety or bioavailability of this drug. [72], [73]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Escherichia coli co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) metabolizes the drug Indomethacin, and Escherichia coli further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [4], [74]
                              Norethindrone acetate Click to Show/Hide the Detail
                                 Drug ID DR1750   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Escherichia coli co-metabolize the drug Norethindrone acetate, which can collectively affect efficacy, safety or bioavailability of this drug. [], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Escherichia coli co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Escherichia coli co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Helicobacter apodemus (epsilon-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Helicobacter apodemus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [51], [52]
                  Klebsiella aerogenes (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Klebsiella aerogenes co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [70]
                  Klebsiella pneumoniae (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Klebsiella pneumoniae co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [70]
                  Neisseria sicca (beta-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Neisseria sicca co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [46]
                  Photorhabdus asymbiotica (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Photorhabdus asymbiotica co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [75], [76]
                  Proteus penneri (enterobacteria) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Chloramphenicol Click to Show/Hide the Detail
                                 Drug ID DR0298   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Proteus penneri co-metabolize the drug Chloramphenicol, which can collectively affect efficacy, safety or bioavailability of this drug. [61], [62]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Proteus penneri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Proteus penneri co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Proteus penneri co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Proteus penneri co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Providencia alcalifaciens (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Providencia alcalifaciens co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Providencia alcalifaciens co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Providencia rettgeri (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Providencia rettgeri co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Providencia rettgeri co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Providencia stuartii (enterobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Providencia stuartii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Providencia stuartii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Providencia stuartii co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Providencia stuartii co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Pseudomonas putida (gamma-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Nicotine Click to Show/Hide the Detail
                                 Drug ID DR1148   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Pseudomonas putida co-metabolize the drug Nicotine, which can collectively affect efficacy, safety or bioavailability of this drug. [77], [78]
                  Salmonella enterica (enterobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Salmonella enterica co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [79]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Salmonella enterica co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Salmonella enterica co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Salmonella enterica co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Shigella sonnei (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Amoxicillin Click to Show/Hide the Detail
                                 Drug ID DR0104   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Shigella sonnei co-metabolize the drug Amoxicillin, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [80]
                  Sphingomonas colocasiae (alpha-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Ibuprofen Click to Show/Hide the Detail
                                 Drug ID DR0844   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Sphingomonas colocasiae co-metabolize the drug Ibuprofen, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [81]
      Bacteria: Verrucomicrobia
                  Akkermansia muciniphila (verrucomicrobiae) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Naftopidil Click to Show/Hide the Detail
                                 Drug ID DR1124   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Akkermansia muciniphila co-metabolize the drug Naftopidil, which can collectively affect efficacy, safety or bioavailability of this drug. [39], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Akkermansia muciniphila co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Pantoprazole sodium Click to Show/Hide the Detail
                                 Drug ID DR1236   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Akkermansia muciniphila co-metabolize the drug Pantoprazole sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
      Archaea: Euryarchaeota
                  Methanobrevibacter oralis (methanobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Chloramphenicol Click to Show/Hide the Detail
                                 Drug ID DR0298   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Methanobrevibacter oralis co-metabolize the drug Chloramphenicol, which can collectively affect efficacy, safety or bioavailability of this drug. [61], [82]
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Methanobrevibacter oralis co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [82]
                  Methanobrevibacter smithii (methanobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Chloramphenicol Click to Show/Hide the Detail
                                 Drug ID DR0298   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Methanobrevibacter smithii co-metabolize the drug Chloramphenicol, which can collectively affect efficacy, safety or bioavailability of this drug. [61], [82]
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Methanobrevibacter smithii co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [82]
                  Methanomassiliicoccus luminyensis (thermoplasmata) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Chloramphenicol Click to Show/Hide the Detail
                                 Drug ID DR0298   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Methanomassiliicoccus luminyensis co-metabolize the drug Chloramphenicol, which can collectively affect efficacy, safety or bioavailability of this drug. [61], [82]
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Methanomassiliicoccus luminyensis co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [82]
                  Methanosphaera stadtmanae (methanobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Mephenytoin 4-hydroxylase (CYP2C19) and Methanosphaera stadtmanae co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [82]
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