General Information of Drug Metabolite (DM) (ID: DM001485)
DM Name
Bromfenac indolinone
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Cytochrome P450 1A2 (CYP1A2) DME0003 Unclear - Unclear Bromfenac [1] , [2]
Cytochrome P450 1A2 (CYP1A2) DME0003 Unclear - Unclear Bromfenac [1] , [2]
Cytochrome P450 2B6 (CYP2B6) DME0020 Unclear - Unclear Bromfenac [1] , [2]
Cytochrome P450 2C9 (CYP2C9) DME0019 Unclear - Unclear Bromfenac [1] , [2]
Cytochrome P450 2D6 (CYP2D6) DME0009 Unclear - Unclear Bromfenac [1] , [2]
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear Bromfenac [1] , [2]
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear Bromfenac [1] , [2]
Cytochrome P450 3A5 (CYP3A5) DME0012 Unclear - Unclear Bromfenac [1] , [2]
Mephenytoin 4-hydroxylase (CYP2C19) DME0021 Unclear - Unclear Bromfenac [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Bromfenac DR1765 Approved Cataract
References
1 Metabolite profiling and reaction phenotyping for the in vitro assessment of the bioactivation of bromfenac. Chem Res Toxicol. 2020 Jan 21;33(1):249-257.
2 Metabolic disposition of 14C-bromfenac in healthy male volunteers J Clin Pharmacol. 1998 Aug;38(8):744-52. doi: 10.1002/j.1552-4604.1998.tb04815.x.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.