Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000046)
Formula
SVG example
Reactant Acetaldehyde Product Acetic acid
Reactant Info Product Info
Metabolic Enzyme Aldehyde dehydrogenase 1 (ALDH1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007451 Acetaldehyde Acetate Unclear Ethanol [1]
MR004210 Acetaldehyde Ethanol Unclear D-xylulose [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008003 Cefuroxime axetil Acetic acid Unclear - Unclear Cefuroxime axetil [3]
MR001403 Lactulose Acetic acid Oxidation - N-Dealkylation Lactulose [4]
MR008929 HEDP Acetic acid Unclear - Unclear Fotemustine [5]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000045 Acetic acid Acetyl-CoA Unclear Acetaldehyde [6], [7], [8]
References
1 Ethanol Metabolism in the Liver, the Induction of Oxidant Stress, and the Antioxidant Defense System
2 Effects of increased transaldolase activity on D-xylulose and D-glucose metabolism in Saccharomyces cerevisiae cell extracts
3 DrugBank(Pharmacology-Metabolism):Cefuroxime axetil
4 LABEL:ACTULOSE- lactulose solution
5 Disposition, pharmacokinetics, and metabolism of 14C-fotemustine in cancer patients
6 [The metabolism of alcohol] Rev Med Liege. 2019 May;74(5-6):265-267.
7 Characterization of Thermotoga neapolitana Alcohol Dehydrogenases in the Ethanol Fermentation Pathway. Biology (Basel). 2022 Sep 5;11(9):1318. doi: 10.3390/biology11091318.
8 ALDH1A3 Coordinates Metabolism With Gene Regulation in Pulmonary Arterial Hypertension. Circulation. 2021 May 25;143(21):2074-2090. doi: 10.1161/CIRCULATIONAHA.120.048845.

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