Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000045)
Formula
SVG example
Reactant Acetic acid Product Acetyl-CoA
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000046 Acetaldehyde Acetic acid Unclear Acetaldehyde [1], [2], [3]
MR008003 Cefuroxime axetil Acetic acid Unclear - Unclear Cefuroxime axetil [4]
MR001403 Lactulose Acetic acid Oxidation - N-Dealkylation Lactulose [5]
MR007450 Acetaldehyde Acetic acid Oxidation - Oxidationn Ethanol [6]
MR004211 Acetaldehyde Acetic acid Unclear D-xylulose [7]
MR008929 HEDP Acetic acid Unclear - Unclear Fotemustine [8]
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Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012773 Azelaic Acid Acetyl CoA Oxidation - Oxidation Azelaic Acid [9]
MR003886 DB-053072 Acetyl-coA Unclear DB-053072 [10]
MR004455 Oxoglutarate Acetyl-CoA Unclear Oxoglutarate [11]
MR006974 Acetoacetyl-CoA Acetyl coenzyme A Unclear HSDB-41 [12]
MR004899 Undecanoate Acetyl Coenzyme A Oxidation - Oxidationn Testosterone undecanoate [13]
MR005600 Beta-Ketophenylbutyryl-CoA Acetyl-CoA Unclear Sodium phenylbutyrate [14]
MR013771 Beta-Ketophenylbutyryl-CoA Acetyl-CoA Unclear - Unclear phenylbutyrate [15]
MR004003 2-amino-3-muconicsemi-aldehyde Acetyl-CoA Unclear TRP-01 [16]
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Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004900 Acetyl Coenzyme A Propionyl Coenzyme A Oxidation - Oxidationn Testosterone undecanoate [13]
References
1 Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism Mol Psychiatry. 2004 Jun;9(6):570-81. doi: 10.1038/sj.mp.4001497.
2 Metabolism of acetaldehyde and custers effect in the yeast Antonie Van Leeuwenhoek. 1981;47(3):209-15. doi: 10.1007/BF00403392.
3 Characterization of Thermotoga neapolitana Alcohol Dehydrogenases in the Ethanol Fermentation Pathway. Biology (Basel). 2022 Sep 5;11(9):1318. doi: 10.3390/biology11091318.
4 DrugBank(Pharmacology-Metabolism):Cefuroxime axetil
5 LABEL:ACTULOSE- lactulose solution
6 Ethanol Metabolism in the Liver, the Induction of Oxidant Stress, and the Antioxidant Defense System
7 Effects of increased transaldolase activity on D-xylulose and D-glucose metabolism in Saccharomyces cerevisiae cell extracts
8 Disposition, pharmacokinetics, and metabolism of 14C-fotemustine in cancer patients
9 Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders
10 Detection of Bacteria-Specific Metabolism Using Hyperpolarized [2-(13)C]Pyruvate
11 The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite
12 The human gastric pathogen Helicobacter pylori has a potential acetone carboxylase that enhances its ability to colonize mice. BMC Microbiol. 2008 Jan 23;8:14.
13 DrugBank(Pharmacology-Metabolism):Testosterone undecanoate
14 Evidence for involvement of medium chain acyl-CoA dehydrogenase in the metabolism of phenylbutyrate
15 Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: safety, pharmacokinetics and ammonia control
16 Neurotoxicity of tryptophan metabolites

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