General Information of Xenobiotics (ID: XEO03790)
Xenobiotics Name
Peptide LAK80-P10
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 0.82 microM [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 0.82 microM [1]
Beta-lactamase (blaB) DME Info MIC = 0.82 microM [1]
Chloramphenicolase (chlR) DME Info MIC = 0.82 microM [1]
Glycoside hydrolase (cscA) DME Info MIC = 0.82 microM [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 0.82 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.82 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 0.82 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.82 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 1.18 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.82 microM [1]
Glutamate racemase (MurI) DME Info MIC = 0.82 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 1.18 microM [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 0.82 microM [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.82 microM [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.82 microM [1]
NADH dehydrogenase (nuoE) DME Info MIC = 0.82 microM [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 1.18 microM [1]
Tyramine oxidase (tynA) DME Info MIC = 0.82 microM [1]
Beta-glucuronidase (uidA) DME Info MIC = 0.82 microM [1]
References
1 Conformational flexibility determines selectivity and antibacterial, antiplasmodial, and anticancer potency of cationic alpha-helical peptides. J Biol Chem. 2012 Oct 5;287(41):34120-33.

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