Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO04113)
Xenobiotics Name
Microcin J25
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Glutamate decarboxylase (gadB) DME Info Shigella flexneri [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Shigella flexneri [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 0.02 ug/ml [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 0.02 ug/ml [1]
Beta-lactamase (blaB) DME Info MIC = 0.02 ug/ml [1]
Chloramphenicolase (chlR) DME Info MIC = 0.02 ug/ml [1]
Glycoside hydrolase (cscA) DME Info MIC = 0.02 ug/ml [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 0.02 ug/ml [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.02 ug/ml [1]
Glutamate decarboxylase (gadB) DME Info MIC = 0.02 ug/ml [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.02 ug/ml [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.02 ug/ml [1]
Glutamate racemase (MurI) DME Info MIC = 0.02 ug/ml [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 0.02 ug/ml [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.02 ug/ml [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.02 ug/ml [1]
NADH dehydrogenase (nuoE) DME Info MIC = 0.02 ug/ml [2]
Tyramine oxidase (tynA) DME Info MIC = 0.02 ug/ml [1]
Beta-glucuronidase (uidA) DME Info MIC = 0.02 ug/ml [1]
References
1 Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone. J Am Chem Soc. 2003 Oct 15;125(41):12464-74.
2 Structure of antibacterial peptide microcin J25: a 21-residue lariat protoknot. J Am Chem Soc. 2003 Oct 15;125(41):12382-3.

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