Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO04613) | ||||||
|---|---|---|---|---|---|---|
| Xenobiotics Name |
Piscidin Pis-2
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| Xenobiotics Type |
Amino Acid(s), Peptide(s) or Protein(s)
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| Classification |
Peptide
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| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Beta-lactamase (blaB) | DME Info | Serratia marcescens | [1] | |||
| Azoreductase (azoR) | DME Info | Escherichia coli | [1] | |||
| Azoreductase (azoR) | DME Info | Enterococcus faecalis | [1] | |||
| Azoreductase (azoR) | DME Info | Streptococcus pyogenes | [1] | |||
| L,D-carboxypeptidase A (ldcA) | DME Info | Escherichia coli | [1] | |||
| Beta-lactamase (blaB) | DME Info | Klebsiella variicola | [1] | |||
| Beta-lactamase (blaB) | DME Info | Escherichia coli | [1] | |||
| Beta-lactamase (blaB) | DME Info | Salmonella enterica | [1] | |||
| Beta-lactamase (blaB) | DME Info | Klebsiella aerogenes | [1] | |||
| Beta-lactamase (blaB) | DME Info | Enterobacter cloacae | [1] | |||
| Metallo-beta-lactamase (blaM) | DME Info | Klebsiella pneumoniae | [1] | |||
| Beta-lactamase (blaB) | DME Info | Klebsiella pneumoniae | [1] | |||
| Cytidine deaminase (cdd) | DME Info | Escherichia coli | [1] | |||
| Cytidine deaminase (cdd) | DME Info | Klebsiella pneumoniae | [1] | |||
| Chloramphenicolase (chlR) | DME Info | Escherichia coli | [1] | |||
| Carbapenemase (cphA) | DME Info | Aeromonas hydrophila | [1] | |||
| Glycoside hydrolase (cscA) | DME Info | Escherichia coli | [1] | |||
| NADPH-dependent curcumin reductase (curA) | DME Info | Escherichia coli | [1] | |||
| Cytochrome P450 monooxygenase 51A (cyp51A) | DME Info | Aspergillus fumigatus | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Escherichia coli | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Klebsiella pneumoniae | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Enterococcus faecalis | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Salmonella enterica | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | Shigella flexneri | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | Listeria monocytogenes | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | Escherichia coli | [1] | |||
| Beta-galactosidase (bgaB) | DME Info | Enterobacter cloacae | [1] | |||
| L,D-carboxypeptidase A (ldcA) | DME Info | Neisseria gonorrhoeae | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | Escherichia coli | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | Klebsiella pneumoniae | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | Escherichia coli | [1] | |||
| Methylthioribose kinase (mtnK) | DME Info | Klebsiella pneumoniae | [1] | |||
| S-adenosylhomocysteine nucleosidase (mtnN) | DME Info | Klebsiella pneumoniae | [1] | |||
| Glutamate racemase (MurI) | DME Info | Escherichia coli | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Shigella flexneri | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Serratia marcescens | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Pseudomonas aeruginosa | [1] | |||
| N-ethylmaleimide reductase (nemA) | DME Info | Escherichia coli | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | Staphylococcus aureus | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | Escherichia coli | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | Salmonella enterica | [1] | |||
| Nitroreductase (NTR) | DME Info | Enterobacter cloacae | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | Escherichia coli | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | Salmonella enterica | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Klebsiella pneumoniae | [1] | |||
| NADH dehydrogenase (nuoE) | DME Info | Streptomyces griseus | [1] | |||
| Beta-lactamase (blaB) | DME Info | Burkholderia cepacia | [1] | |||
| PenA beta-lactamase (penA1) | DME Info | Burkholderia cepacia | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Retro-nitroreductase (rNR) | DME Info | Enterobacter cloacae | [1] | |||
| Tyrosine decarboxylase (tdc) | DME Info | Enterococcus faecalis | [1] | |||
| Tyramine oxidase (tynA) | DME Info | Escherichia coli | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | Streptococcus agalactiae | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | Escherichia coli | [1] | |||
| VanA ligase (vanA) | DME Info | Enterococcus faecalis | [1] | |||
| VanB ligase (vanB) | DME Info | Enterococcus faecalis | [1] | |||
| VanG ligase (vanG) | DME Info | Streptococcus agalactiae | [1] | |||
| Xenobiotics-DME Activity Data | ||||||
| Xenobiotics-DME Activity Data | Beta-lactamase (blaB) | DME Info | MIC > 20 microM | [1] | ||
| Azoreductase (azoR) | DME Info | MIC = 5-10 microM | [1] | |||
| Azoreductase (azoR) | DME Info | MIC = 5-10 microM | [1] | |||
| Azoreductase (azoR) | DME Info | MIC = 1.25-2.5 microM | [1] | |||
| L,D-carboxypeptidase A (ldcA) | DME Info | MIC = 5-10 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 5-10 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 10-20 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 10-20 microM | [1] | |||
| Metallo-beta-lactamase (blaM) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Cytidine deaminase (cdd) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Cytidine deaminase (cdd) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Chloramphenicolase (chlR) | DME Info | MIC = 5-10 microM | [1] | |||
| Carbapenemase (cphA) | DME Info | MIC > 20 microM | [1] | |||
| Glycoside hydrolase (cscA) | DME Info | MIC = 5-10 microM | [1] | |||
| NADPH-dependent curcumin reductase (curA) | DME Info | MIC = 5-10 microM | [1] | |||
| Cytochrome P450 monooxygenase 51A (cyp51A) | DME Info | MIC = 50-100 microM | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 5-10 microM | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 5-10 microM | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 10-20 microM | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | MIC = 5-10 microM | [1] | |||
| Beta-galactosidase (bgaB) | DME Info | MIC = 10-20 microM | [1] | |||
| L,D-carboxypeptidase A (ldcA) | DME Info | MIC > 20 microM | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | MIC = 5-10 microM | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | MIC = 5-10 microM | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | MIC = 5-10 microM | [1] | |||
| Methylthioribose kinase (mtnK) | DME Info | MIC = 2.5-5 microM | [1] | |||
| S-adenosylhomocysteine nucleosidase (mtnN) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Glutamate racemase (MurI) | DME Info | MIC = 5-10 microM | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC = 2.5-5 microM | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC > 20 microM | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC = 5-10 microM | [1] | |||
| N-ethylmaleimide reductase (nemA) | DME Info | MIC = 5-10 microM | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | MIC = 1.25-2.5 microM | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | MIC = 5-10 microM | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | MIC = 10-20 microM | [1] | |||
| Nitroreductase (NTR) | DME Info | MIC = 10-20 microM | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | MIC = 5-10 microM | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | MIC = 10-20 microM | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC = 2.5-5 microM | [1] | |||
| NADH dehydrogenase (nuoE) | DME Info | MIC = 5-10 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC > 20 microM | [1] | |||
| PenA beta-lactamase (penA1) | DME Info | MIC > 20 microM | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | MIC = 5-10 microM | [1] | |||
| Retro-nitroreductase (rNR) | DME Info | MIC = 10-20 microM | [1] | |||
| Tyrosine decarboxylase (tdc) | DME Info | MIC = 5-10 microM | [1] | |||
| Tyramine oxidase (tynA) | DME Info | MIC = 5-10 microM | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | MIC = 1.25-2.5 microM | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | MIC = 5-10 microM | [1] | |||
| VanA ligase (vanA) | DME Info | MIC = 5-10 microM | [1] | |||
| VanB ligase (vanB) | DME Info | MIC = 5-10 microM | [1] | |||
| VanG ligase (vanG) | DME Info | MIC = 1.25-2.5 microM | [1] | |||
| References | ||||||
| 1 | Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem. 2002 Feb 15;277(7):5030-9. | |||||
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