Details of Microbiome-DME Interaction (MICBIO)

General Information of Drug-Metabolizing Enzyme (DME ID: DME0004)
DME Name UDP-glucuronosyltransferase 1A1 (UGT1A1), Homo sapiens DME Info
UniProt ID
UD11_HUMAN
EC Number    EC: 2.4.1.17     (Click to Show/Hide the Complete EC Tree)
Transferase
Glycosyltransferases
Hexosyltransferase
EC: 2.4.1.17
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Interactome
Interactions between Microbiome and DME (MICBIO)
      Bacteria: Actinobacteria
                  Bifidobacterium adolescentis (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium adolescentis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium adolescentis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bifidobacterium breve (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium breve co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium breve co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bifidobacterium longum (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium longum co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [4]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium longum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bifidobacterium ruminatum (actinobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium ruminatum co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium ruminatum co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium ruminatum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bifidobacterium ruminatum co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Collinsella aerofaciens (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Pitavastatin calcium Click to Show/Hide the Detail
                                 Drug ID DR1306   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Collinsella aerofaciens co-metabolize the drug Pitavastatin calcium, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Zidovudine Click to Show/Hide the Detail
                                 Drug ID DR1729   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Collinsella aerofaciens co-metabolize the drug Zidovudine, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Collinsella intestinalis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Collinsella intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Eggerthella lenta (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Eggerthella lenta co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Eggerthella lenta co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Bacteroidetes
                  Alistipes indistinctus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Alistipes indistinctus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Alistipes indistinctus co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Bacteroides caccae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides caccae co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Bacteroides cellulosilyticus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides cellulosilyticus co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides cellulosilyticus co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Bacteroides coprophilus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides coprophilus co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides coprophilus co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides coprophilus co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides coprophilus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naloxone Click to Show/Hide the Detail
                                 Drug ID DR1127   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides coprophilus co-metabolize the drug Naloxone, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [2]
                  Bacteroides dorei (CFB bacteria) Click to Show/Hide the Full List of Drugs:      10 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Repaglinide Click to Show/Hide the Detail
                                 Drug ID DR1404   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Repaglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides dorei co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Bacteroides eggerthii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides eggerthii co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides eggerthii co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides eggerthii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides eggerthii co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Bacteroides fragilis (CFB bacteria) Click to Show/Hide the Full List of Drugs:      17 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [2]
                              Ezetimibe Click to Show/Hide the Detail
                                 Drug ID DR0677   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Ezetimibe, which can collectively affect efficacy, safety or bioavailability of this drug. [16], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [18], [19]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naloxone Click to Show/Hide the Detail
                                 Drug ID DR1127   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Naloxone, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [2]
                              Repaglinide Click to Show/Hide the Detail
                                 Drug ID DR1404   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Repaglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Warfarin sodium Click to Show/Hide the Detail
                                 Drug ID DR1717   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides fragilis co-metabolize the drug Warfarin sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                  Bacteroides intestinalis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides intestinalis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides ovatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides ovatus co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides ovatus co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides ovatus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naloxone Click to Show/Hide the Detail
                                 Drug ID DR1127   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides ovatus co-metabolize the drug Naloxone, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides ovatus co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides ovatus co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Bacteroides sartorii (CFB bacteria) Click to Show/Hide the Full List of Drugs:      15 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [2]
                              Ezetimibe Click to Show/Hide the Detail
                                 Drug ID DR0677   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Ezetimibe, which can collectively affect efficacy, safety or bioavailability of this drug. [16], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                              Itraconazole Click to Show/Hide the Detail
                                 Drug ID DR0895   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Itraconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naloxone Click to Show/Hide the Detail
                                 Drug ID DR1127   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Naloxone, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [2]
                              Repaglinide Click to Show/Hide the Detail
                                 Drug ID DR1404   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Repaglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides sartorii co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Bacteroides stercoris (CFB bacteria) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides stercoris co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Ezetimibe Click to Show/Hide the Detail
                                 Drug ID DR0677   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides stercoris co-metabolize the drug Ezetimibe, which can collectively affect efficacy, safety or bioavailability of this drug. [16], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides stercoris co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides stercoris co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides stercoris co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides stercoris co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Bacteroides thetaiotaomicron (CFB bacteria) Click to Show/Hide the Full List of Drugs:      14 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [2]
                              Ezetimibe Click to Show/Hide the Detail
                                 Drug ID DR0677   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Ezetimibe, which can collectively affect efficacy, safety or bioavailability of this drug. [16], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [4]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naloxone Click to Show/Hide the Detail
                                 Drug ID DR1127   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Naloxone, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [2]
                              Repaglinide Click to Show/Hide the Detail
                                 Drug ID DR1404   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Repaglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              SN-38 Click to Show/Hide the Detail
                                 Drug ID DR0024   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug SN-38, while Bacteroides thetaiotaomicron further converts its metabolite SN-38G back to SN-38, which leads to delayed-onset, severe diarrhea and limits the effective dose administered. [23], [24]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides thetaiotaomicron co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Bacteroides uniformis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides uniformis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides uniformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              SN-38 Click to Show/Hide the Detail
                                 Drug ID DR0024   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug SN-38, while Bacteroides uniformis further converts its metabolite SN-38G back to SN-38, which leads to delayed-onset, severe diarrhea and limits the effective dose administered. [23], [24]
                  Bacteroides vulgatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:      11 Drugs Metabolized
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug Indomethacin, and Bacteroides vulgatus further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [25]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [2]
                              Repaglinide Click to Show/Hide the Detail
                                 Drug ID DR1404   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Repaglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Warfarin sodium Click to Show/Hide the Detail
                                 Drug ID DR1717   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides vulgatus co-metabolize the drug Warfarin sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                  Bacteroides xylanisolvens (CFB bacteria) Click to Show/Hide the Full List of Drugs:      13 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [2]
                              Ezetimibe Click to Show/Hide the Detail
                                 Drug ID DR0677   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Ezetimibe, which can collectively affect efficacy, safety or bioavailability of this drug. [16], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [2]
                              Repaglinide Click to Show/Hide the Detail
                                 Drug ID DR1404   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Repaglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides xylanisolvens co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Odoribacter laneus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Epinephrine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0590   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter laneus co-metabolize the drug Epinephrine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [27]
                  Odoribacter splanchnicus (CFB bacteria) Click to Show/Hide the Full List of Drugs:      14 Drugs Metabolized
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [2]
                              Ezetimibe Click to Show/Hide the Detail
                                 Drug ID DR0677   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Ezetimibe, which can collectively affect efficacy, safety or bioavailability of this drug. [16], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                              Itraconazole Click to Show/Hide the Detail
                                 Drug ID DR0895   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Itraconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [2]
                              Repaglinide Click to Show/Hide the Detail
                                 Drug ID DR1404   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Repaglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Odoribacter splanchnicus co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Parabacteroides distasonis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides distasonis co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides distasonis co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides distasonis co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides distasonis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides distasonis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides distasonis co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides distasonis co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Telmisartan Click to Show/Hide the Detail
                                 Drug ID DR1545   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides distasonis co-metabolize the drug Telmisartan, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                  Parabacteroides johnsonii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides johnsonii co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides johnsonii co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides johnsonii co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides johnsonii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Parabacteroides merdae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides merdae co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides merdae co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides merdae co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides merdae co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides merdae co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Parabacteroides merdae co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Prevotella copri (CFB bacteria) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Prevotella copri co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [29]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Prevotella copri co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Prevotella copri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Naloxone Click to Show/Hide the Detail
                                 Drug ID DR1127   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Prevotella copri co-metabolize the drug Naloxone, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Prevotella copri co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
      Bacteria: Firmicutes
                  Anaerobutyricum hallii (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Anaerobutyricum hallii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Anaerococcus hydrogenalis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Anaerococcus hydrogenalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Zidovudine Click to Show/Hide the Detail
                                 Drug ID DR1729   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Anaerococcus hydrogenalis co-metabolize the drug Zidovudine, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Anaerostipes hadrus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Anaerostipes hadrus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacillus megaterium (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacillus megaterium co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [31]
                  Bacillus pumilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Gemfibrozil Click to Show/Hide the Detail
                                 Drug ID DR0766   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacillus pumilus co-metabolize the drug Gemfibrozil, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [33]
                  Bacteroides pectinophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Bacteroides pectinophilus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Blautia hansenii (firmicutes) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Anastrozole Click to Show/Hide the Detail
                                 Drug ID DR0113   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia hansenii co-metabolize the drug Anastrozole, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia hansenii co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia hansenii co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia hansenii co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia hansenii co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Itraconazole Click to Show/Hide the Detail
                                 Drug ID DR0895   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia hansenii co-metabolize the drug Itraconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia hansenii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia hansenii co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Blautia luti (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Itraconazole Click to Show/Hide the Detail
                                 Drug ID DR0895   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia luti co-metabolize the drug Itraconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Blautia luti co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridioides difficile (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridioides difficile co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [35]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridioides difficile co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium botulinum (firmicutes) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Anastrozole Click to Show/Hide the Detail
                                 Drug ID DR0113   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium botulinum co-metabolize the drug Anastrozole, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium botulinum co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Ezetimibe Click to Show/Hide the Detail
                                 Drug ID DR0677   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium botulinum co-metabolize the drug Ezetimibe, which can collectively affect efficacy, safety or bioavailability of this drug. [16], [2]
                              Febuxostat Click to Show/Hide the Detail
                                 Drug ID DR0681   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium botulinum co-metabolize the drug Febuxostat, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Itraconazole Click to Show/Hide the Detail
                                 Drug ID DR0895   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium botulinum co-metabolize the drug Itraconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium botulinum co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium botulinum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium botulinum co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Clostridium perfringens (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium perfringens co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [4]
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium perfringens co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [36]
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium perfringens co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [36]
                              SN-38 Click to Show/Hide the Detail
                                 Drug ID DR0024   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug SN-38, while Clostridium perfringens further converts its metabolite SN-38G back to SN-38, which leads to delayed-onset, severe diarrhea and limits the effective dose administered. [23], [37]
                  Clostridium scindens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium scindens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium spiroforme (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium spiroforme co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium sporogenes (firmicutes) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium sporogenes co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Digitoxin Click to Show/Hide the Detail
                                 Drug ID DR0497   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium sporogenes co-metabolize the drug Digitoxin, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Ezetimibe Click to Show/Hide the Detail
                                 Drug ID DR0677   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium sporogenes co-metabolize the drug Ezetimibe, which can collectively affect efficacy, safety or bioavailability of this drug. [16], [2]
                              Itraconazole Click to Show/Hide the Detail
                                 Drug ID DR0895   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium sporogenes co-metabolize the drug Itraconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium sporogenes co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Zonisamide Click to Show/Hide the Detail
                                 Drug ID DR1737   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Clostridium sporogenes co-metabolize the drug Zonisamide, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [39]
                  Coprococcus comes (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Coprococcus comes co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Dorea formicigenerans (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Dorea formicigenerans co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterocloster asparagiformis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterocloster asparagiformis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterocloster asparagiformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterocloster bolteae (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterocloster bolteae co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterococcus casseliflavus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterococcus casseliflavus co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [40]
                  Enterococcus faecalis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterococcus faecalis co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [35]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterococcus faecalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterococcus gallinarum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterococcus gallinarum co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [40]
                  Erysipelatoclostridium ramosum (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug Indomethacin, and Erysipelatoclostridium ramosum further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [25]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Erysipelatoclostridium ramosum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Erysipelatoclostridium ramosum co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Eubacterium limosum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Eubacterium limosum co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [4]
                  Eubacterium rectale (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Eubacterium rectale co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Holdemanella biformis (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Holdemanella biformis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Holdemanella biformis co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Holdemanella biformis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Holdemanella biformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Hungatella hathewayi (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Hungatella hathewayi co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Jeotgalicoccus psychrophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Jeotgalicoccus psychrophilus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [29]
                  Lactobacillus gasseri (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Bazedoxifene Click to Show/Hide the Detail
                                 Drug ID DR0177   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Lactobacillus gasseri co-metabolize the drug Bazedoxifene, which can collectively affect efficacy, safety or bioavailability of this drug. [41], [42]
                  Lactobacillus reuteri (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Lactobacillus reuteri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Lactobacillus reuteri co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Marvinbryantia formatexigens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Marvinbryantia formatexigens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Roseburia hominis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug Indomethacin, and Roseburia hominis further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [25]
                  Roseburia intestinalis (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Roseburia intestinalis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug Indomethacin, and Roseburia intestinalis further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [25]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Roseburia intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Roseburia intestinalis co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                  Ruminococcus albus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Ruminococcus albus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [29]
                  Ruminococcus torques (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Ruminococcus torques co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Streptococcus agalactiae (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              SN-38 Click to Show/Hide the Detail
                                 Drug ID DR0024   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug SN-38, while Streptococcus agalactiae further converts its metabolite SN-38G back to SN-38, which leads to delayed-onset, severe diarrhea and limits the effective dose administered. [23], [37]
                  Subdoligranulum variabile (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Subdoligranulum variabile co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Subdoligranulum variabile co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
      Bacteria: Fusobacteria
                  Fusobacterium varium (fusobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Fusobacterium varium co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [4]
      Bacteria: Lentisphaerae
                  Victivallis vadensis (PVC bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Lovastatin Click to Show/Hide the Detail
                                 Drug ID DR0986   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Victivallis vadensis co-metabolize the drug Lovastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Victivallis vadensis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Proteobacteria
                  Citrobacter freundii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Citrobacter freundii co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [35]
                  Edwardsiella tarda (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Edwardsiella tarda co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterobacter cancerogenus (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterobacter cancerogenus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterobacter cloacae (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Enterobacter cloacae co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [43]
                  Escherichia coli (enterobacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Escherichia coli co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [35]
                              Curcumin Click to Show/Hide the Detail
                                 Drug ID DR1941   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Escherichia coli co-metabolize the drug Curcumin, which can collectively affect efficacy, safety or bioavailability of this drug. [44], [45]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug Indomethacin, and Escherichia coli further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [17], [46]
                              Irinotecan hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0881   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Escherichia coli co-metabolize the drug Irinotecan hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [47]
                              Ketoprofen Click to Show/Hide the Detail
                                 Drug ID DR0907   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug Ketoprofen, and Escherichia coli further metabolizes its metabolite (Ketoprofen glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [48], [49]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Escherichia coli co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              SN-38 Click to Show/Hide the Detail
                                 Drug ID DR0024   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug SN-38, while Escherichia coli further converts its metabolite SN-38G back to SN-38, which leads to delayed-onset, severe diarrhea and limits the effective dose administered. [23], [47]
                  Helicobacter apodemus (epsilon-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Helicobacter apodemus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [29]
                  Neisseria sicca (beta-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Ethanol Click to Show/Hide the Detail
                                 Drug ID DR0655   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Neisseria sicca co-metabolize the drug Ethanol, which can collectively affect efficacy, safety or bioavailability of this drug. [50], [51]
                  Proteus penneri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Proteus penneri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Providencia alcalifaciens (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Providencia alcalifaciens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Providencia rettgeri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Providencia rettgeri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Providencia stuartii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Providencia stuartii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Pseudomonas putida (gamma-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Nicotine Click to Show/Hide the Detail
                                 Drug ID DR1148   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Pseudomonas putida co-metabolize the drug Nicotine, which can collectively affect efficacy, safety or bioavailability of this drug. [52], [53]
                  Salmonella enterica (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Salmonella enterica co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Verrucomicrobia
                  Akkermansia muciniphila (verrucomicrobiae) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Itraconazole Click to Show/Hide the Detail
                                 Drug ID DR0895   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Akkermansia muciniphila co-metabolize the drug Itraconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Akkermansia muciniphila co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Riluzole Click to Show/Hide the Detail
                                 Drug ID DR1425   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Akkermansia muciniphila co-metabolize the drug Riluzole, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
      Fungi: Ascomycota
                  Saccharomyces cerevisiae (ascomycota) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes the drug Acetaminophen, and Saccharomyces cerevisiae further metabolizes its metabolite (1-Phenyl-1,2-propanedione), which can indirectly affect efficacy, safety or bioavailability of this drug. [30], [35]
      Amoebozoa: Evosea
                  Entamoeba histolytica (eukaryotes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Entamoeba histolytica co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [54]
      Metamonada: Fornicata
                  Giardia intestinalis (diplomonads) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Giardia intestinalis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [54]
      Metamonada: Parabasalia
                  Trichomonas vaginalis (trichomonads) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A1 (UGT1A1) and Trichomonas vaginalis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [54]
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