Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1104)
DME Name Arylamine N-acetyltransferase (NAT), Serratia marcescens DME Info
UniProt ID
A0A1C3HAL9_SERMA
EC Number    EC: 2.3.1.5     (Click to Show/Hide the Complete EC Tree)
Transferase
Acyltransferase
Acyltransferase
EC: 2.3.1.5
Lineage    Species: Serratia marcescens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Yersiniaceae
Genus: Serratia
Species: Serratia marcescens
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:      42 Xenobiotics
                              Acaloleptin-A1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02117   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Acaloleptin-A1 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [1], [2]
                              Acaloleptin-A2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02118   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Acaloleptin-A2 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [1], [2]
                              Acaloleptin-A3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02119   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Acaloleptin-A3 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [1], [2]
                              Acaloleptin-A4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02120   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Acaloleptin-A4 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [1], [2]
                              Acaloleptin-A5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02121   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Acaloleptin-A5 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [1], [2]
                              Andropin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02226   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Andropin inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 127 microM) [3]
                              Antimicrobial protein AN5-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02298   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial protein AN5-1 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 32 ug/ml) [4]
                              Bovine cathelicidin BMAP-34 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02466   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bovine cathelicidin BMAP-34 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 1.5 microM) [5], [6]
                              Bradykinin-potentiating BmK3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02491   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bradykinin-potentiating BmK3 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 68.2 microM) [7], [8]
                              Cathelicidin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02731   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cathelicidin inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 4 microM) [9], [10]
                              Cathelicidin-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02739   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cathelicidin-5 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 2 microM) [11], [12]
                              Cathelicidin-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02740   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cathelicidin-6 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 2 ug/ml) [11], [13]
                              D-amino-acid pexiganan MSI-214 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03073   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation D-amino-acid pexiganan MSI-214 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 256 ug/ml) [14]
                              Drosophila cecropin-A1/A2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03225   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Drosophila cecropin-A1/A2 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 93 microM) [15]
                              Gaegurin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03437   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-2 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 200 ug/ml) [16]
                              Gaegurin-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03438   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-3 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 200 ug/ml) [16]
                              Gaegurin-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03439   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-4 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 200 ug/ml) [17]
                              Gaegurin-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03441   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-6 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 200 ug/ml) [16]
                              Hadrurin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03519   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Hadrurin inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [18]
                              Hydramacin Hm-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03609   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Hydramacin Hm-1 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [19], [20]
                              Immune protein P9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02769   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Immune protein P9 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 2.2 microM) [21]
                              Insect attacin-C Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02333   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect attacin-C inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 200 microM) [22]
                              Insect cecropin-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02768   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect cecropin-A inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [21]
                              Insect cecropin-D Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02772   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect cecropin-D inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [21], [23]
                              Insect defensin A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03116   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect defensin A inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 40 microM) [24]
                              M-zodatoxin-Lt8c Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04185   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-zodatoxin-Lt8c inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [25]
                              Magainin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03985   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Magainin-2 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 100 ug/ml) [26], [27]
                              Mammal mBMAP28 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04039   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mammal mBMAP28 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 4 microM) [11]
                              Myeloid antimicrobial peptide BMAP-27 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04158   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Myeloid antimicrobial peptide BMAP-27 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 2 microM) [11]
                              Myeloid antimicrobial peptide BMAP-28 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04159   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Myeloid antimicrobial peptide BMAP-28 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 2 microM) [11]
                              Opistoporin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04399   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Opistoporin-1 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC = 50 microM) [28]
                              Piscidin Pis-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04612   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Piscidin Pis-1 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 20 microM) [29]
                              Piscidin Pis-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04613   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Piscidin Pis-2 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 20 microM) [30]
                              Pleurocidin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04640   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens (MIC > 35.0 microM) [31]
                              Ponericin G1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04695   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin G1 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [32]
                              Ponericin G3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04696   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin G3 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [32]
                              Ponericin-L2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04699   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-L2 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [32]
                              Ponericin-W1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04700   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W1 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [32]
                              Ponericin-W3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04701   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W3 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [32]
                              Ponericin-W4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04702   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W4 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [32]
                              Ponericin-W5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04703   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W5 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [32]
                              Ponericin-W6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04704   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W6 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [32]
      Health or Environmental Toxicant(s)
                  Acute Toxic Substance Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Oxyquinoline Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01419   XEOTIC Info Gene Form Protein
                                 Classification Acute Toxic Substance
                                 DME Modulation Oxyquinoline inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [33]
      Natural Product(s), Extract(s) or Medicine(s)
                  Bacterial Extract Click to Show/Hide the Full List of Xenobiotics:        2 Xenobiotics
                              Coral associated bacteria 23 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02912   XEOTIC Info Gene Form Protein
                                 Classification Bacterial Extract
                                 DME Modulation Coral associated bacteria 23 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [34]
                              Coral associated bacteria 41 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02913   XEOTIC Info Gene Form Protein
                                 Classification Bacterial Extract
                                 DME Modulation Coral associated bacteria 41 inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [34]
                  Natural Product Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              2,4-Di-tert-butylphenol Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04557   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation 2,4-Di-tert-butylphenol inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [35]
                  Plant Extract Click to Show/Hide the Full List of Xenobiotics:        4 Xenobiotics
                              Burdock roots methanol extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04086   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Burdock roots methanol extract inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [36]
                              Capparis spinosa methanolic extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04089   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Capparis spinosa methanolic extract inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [37]
                              Hyptis suaveolens hexane extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03552   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Hyptis suaveolens hexane extract inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [38]
                              Piper betle ethyl acetate extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03354   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Piper betle ethyl acetate extract inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [39]
                  Sponge Extract Click to Show/Hide the Full List of Xenobiotics:        3 Xenobiotics
                              Aphrocallistes bocagei methanol extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04081   XEOTIC Info Gene Form Protein
                                 Classification Sponge Extract
                                 DME Modulation Aphrocallistes bocagei methanol extract inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [40]
                              Clathria atrasanguinea methanol extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04082   XEOTIC Info Gene Form Protein
                                 Classification Sponge Extract
                                 DME Modulation Clathria atrasanguinea methanol extract inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [40]
                              Haliclona megastoma methanol extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04083   XEOTIC Info Gene Form Protein
                                 Classification Sponge Extract
                                 DME Modulation Haliclona megastoma methanol extract inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [40]
      Pharmaceutical Agent(s)
                  Drug in Phase 3 Clinical Trial Click to Show/Hide the Full List of Xenobiotics:        2 Xenobiotics
                              Curcumin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00683   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 3
                                 DME Modulation Curcumin inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [41]
                              Epigallocatechin gallate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00613   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 3
                                 DME Modulation Epigallocatechin gallate inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [42]
                  Drug in Phase 2 Clinical Trial Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Butane-1,4-diamine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02654   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 2
                                 DME Modulation Butane-1,4-diamine inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [33]
                  Drug in Phase 1 Clinical Trial Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Phenanthrene Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00574   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 1
                                 DME Modulation Phenanthrene inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [38]
                  Investigative Agent Click to Show/Hide the Full List of Xenobiotics:        2 Xenobiotics
                              Ethane-1,2-diamine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03340   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Ethane-1,2-diamine inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [33]
                              Undecanoic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05199   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Undecanoic acid inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [38]
      Other Chemical Compound(s) or Element(s)
                  Chemical Compound Click to Show/Hide the Full List of Xenobiotics:        3 Xenobiotics
                              1,8-Diaminooctane Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04352   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation 1,8-Diaminooctane inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [33]
                              7-chloroquinolin-4-ol Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02091   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation 7-chloroquinolin-4-ol inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [33]
                              N1-(7-chloroquinolin-4-yl)ethane-1,2-diamine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04208   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation N1-(7-chloroquinolin-4-yl)ethane-1,2-diamine inhibits the drug-metabolizing activity of Arylamine N-acetyltransferase (NAT) from Serratia marcescens [33]
References
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3 The andropin gene and its product, a male-specific antibacterial peptide in Drosophila melanogaster. EMBO J. 1991 Jan;10(1):163-9.
4 Detection of secreted antimicrobial peptides isolated from cell-free culture supernatant of Paenibacillus alvei AN5. J Ind Microbiol Biotechnol. 2013 Jun;40(6):571-9.
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13 Sequence analysis and polymorphism discovery in 4 members of the bovine cathelicidin gene family. J Hered. 2009 Mar-Apr;100(2):241-5.
14 In vitro antibacterial properties of pexiganan, an analog of magainin. Antimicrob Agents Chemother. 1999 Apr;43(4):782-8.
15 Molecular evolution of the Cecropin multigene family in Drosophilafunctional genes vspseudogenes. Genetics. 1998 Sep;150(1):157-71.
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17 Solution structure and membrane interaction mode of an antimicrobial peptide gaegurin 4. Biochem Biophys Res Commun. 2007 Jan 19;352(3):592-7.
18 Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus. Eur J Biochem. 2000 Aug;267(16):5023-31.
19 Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence. Dev Comp Immunol. 2009 Apr;33(4):559-69.
20 Hydramacin-1, structure and antibacterial activity of a protein from the basal metazoan Hydra. J Biol Chem. 2009 Jan 16;284(3):1896-905.
21 Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae. Eur J Biochem. 1982 Sep;127(1):207-17.
22 Primary structure and in vitro antibacterial properties of the Drosophila melanogaster attacin C Pro-domain. J Biol Chem. 2004 Apr 9;279(15):14853-9.
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