Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO02739)
Xenobiotics Name
Cathelicidin-5
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Beta-lactamase (blaB) DME Info Serratia marcescens [1], [2]
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Salmonella enterica [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Salmonella enterica [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Serratia marcescens [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Salmonella enterica [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Salmonella enterica [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Beta-lactamase (blaB) DME Info MIC = 2 microM [1], [2]
Azoreductase (azoR) DME Info MIC = 0.5 microM [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 0.5 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 0.5 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 1 microM [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 0.5 microM [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 0.5 microM [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 0.5 microM [1], [2]
Cytochrome P450 102A1 (cyp102) DME Info MIC = 2 microM [1], [2]
Cytochrome P450 MEG (cyp106) DME Info MIC = 2 microM [1], [2]
Cytochrome P450 21A2 (cyp21) DME Info MIC = 2 microM [1], [2]
Cytochrome P450 BM3 (cypBM3) DME Info MIC = 2 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.5 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 1 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 0.5 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.5 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 1 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.5 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 0.5 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 2 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 1 microM [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 0.5 microM [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 1 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.5 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 1 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.5 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 1 microM [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 0.5 microM [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 1 microM [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 0.5 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 0.5 microM [1], [2]
References
1 Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities. J Biol Chem. 1996 Nov 8;271(45):28375-81.
2 Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides. Eur J Biochem. 1996 Jun 15;238(3):769-76.

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