General Information of Xenobiotics (ID: XEO02768)
Xenobiotics Name
Insect cecropin-A
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Beta-lactamase (blaB) DME Info Serratia marcescens [1]
Azoreductase (azoR) DME Info Escherichia coli [2]
Azoreductase (azoR) DME Info Streptococcus pyogenes [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [2]
Beta-lactamase (blaB) DME Info Klebsiella variicola [2]
Beta-lactamase (blaB) DME Info Escherichia coli [2]
Beta-lactamase (blaB) DME Info Salmonella enterica [2]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [2]
Beta-lactamase (blaB) DME Info Enterobacter cloacae [2]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [2]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [2]
Cytidine deaminase (cdd) DME Info Escherichia coli [2]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [2]
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [2]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [2]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [2]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [2]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [2]
Unclear metabolic mechanism (DME-unclear) DME Info Salmonella enterica [2]
Unclear metabolic mechanism (DME-unclear) DME Info Saccharomyces cerevisiae [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [2]
Beta-galactosidase (bgaB) DME Info Enterobacter cloacae [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [2]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [2]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [2]
Glutamate racemase (MurI) DME Info Escherichia coli [2]
Arylamine N-acetyltransferase (NAT) DME Info Serratia marcescens [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [2]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Salmonella enterica [2]
Nitroreductase (NTR) DME Info Enterobacter cloacae [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Salmonella enterica [2]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [2]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1]
Retro-nitroreductase (rNR) DME Info Enterobacter cloacae [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [2]
Glutamate racemase (MurI) DME Info Bacillus pumilus [1]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 0.1-0.25 ug/ml [2]
Azoreductase (azoR) DME Info MIC = 10-25 ug/ml [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 0.1-0.25 ug/ml [2]
Beta-lactamase (blaB) DME Info MIC = 1-2.5 ug/ml [2]
Beta-lactamase (blaB) DME Info MIC = 0.1-0.25 ug/ml [2]
Beta-lactamase (blaB) DME Info MIC = 1-2.5 ug/ml [2]
Beta-lactamase (blaB) DME Info MIC = 1-2.5 ug/ml [2]
Beta-lactamase (blaB) DME Info MIC = 50-100 ug/ml [2]
Metallo-beta-lactamase (blaM) DME Info MIC = 1-2.5 ug/ml [2]
Beta-lactamase (blaB) DME Info MIC = 1-2.5 ug/ml [2]
Cytidine deaminase (cdd) DME Info MIC = 1-2.5 ug/ml [2]
Cytidine deaminase (cdd) DME Info MIC = 1-2.5 ug/ml [2]
Chloramphenicolase (chlR) DME Info MIC = 0.1-0.25 ug/ml [2]
Glycoside hydrolase (cscA) DME Info MIC = 0.1-0.25 ug/ml [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 0.1-0.25 ug/ml [2]
Cytochrome P450 102A1 (cyp102) DME Info MIC = 1-2.5 ug/ml [2]
Cytochrome P450 MEG (cyp106) DME Info MIC = 1-2.5 ug/ml [2]
Cytochrome P450 21A2 (cyp21) DME Info MIC = 1-2.5 ug/ml [2]
Cytochrome P450 BM3 (cypBM3) DME Info MIC = 1-2.5 ug/ml [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.1-0.25 ug/ml [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 1-2.5 ug/ml [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 1-2.5 ug/ml [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 50-100 ug/ml [2]
Glutamate decarboxylase (gadB) DME Info MIC = 0.1-0.25 ug/ml [2]
Beta-galactosidase (bgaB) DME Info MIC = 50-100 ug/ml [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.1-0.25 ug/ml [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 10-25 ug/ml [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 1-2.5 ug/ml [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.1-0.25 ug/ml [2]
Methylthioribose kinase (mtnK) DME Info MIC = 1-2.5 ug/ml [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info MIC = 1-2.5 ug/ml [2]
Glutamate racemase (MurI) DME Info MIC = 0.1-0.25 ug/ml [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 10-25 ug/ml [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 0.1-0.25 ug/ml [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.1-0.25 ug/ml [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 1-2.5 ug/ml [2]
Nitroreductase (NTR) DME Info MIC = 50-100 ug/ml [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.1-0.25 ug/ml [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 1-2.5 ug/ml [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 1-2.5 ug/ml [2]
NADH dehydrogenase (nuoE) DME Info MIC = 0.1-0.25 ug/ml [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 10-25 ug/ml [2]
Retro-nitroreductase (rNR) DME Info MIC = 50-100 ug/ml [2]
Tyramine oxidase (tynA) DME Info MIC = 0.1-0.25 ug/ml [2]
Beta-glucuronidase (uidA) DME Info MIC = 0.1-0.25 ug/ml [2]
References
1 Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae. Eur J Biochem. 1982 Sep;127(1):207-17.
2 Antimicrobial activity spectrum, cDNA cloning, and mRNA expression of a newly isolated member of the cecropin family from the mosquito vector Aedes aegypti. J Biol Chem. 1999 Jul 16;274(29):20092-7.

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