General Information of Xenobiotics (ID: XEO03225)
Xenobiotics Name
Drosophila cecropin-A1/A2
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Beta-lactamase (blaB) DME Info Serratia marcescens [1]
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Enterobacter cloacae [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
Beta-galactosidase (bgaB) DME Info Enterobacter cloacae [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Serratia marcescens [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Nitroreductase (NTR) DME Info Enterobacter cloacae [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [3]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1]
Retro-nitroreductase (rNR) DME Info Enterobacter cloacae [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Bacillus pumilus [1]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Beta-lactamase (blaB) DME Info MIC = 93 microM [1]
Azoreductase (azoR) DME Info MIC = 0.3 microM [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 0.3 microM [1]
Beta-lactamase (blaB) DME Info MIC = 0.3 microM [1]
Beta-lactamase (blaB) DME Info MIC = 0.4 microM [2]
Chloramphenicolase (chlR) DME Info MIC = 0.3 microM [1]
Glycoside hydrolase (cscA) DME Info MIC = 0.3 microM [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 0.3 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.3 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 0.3 microM [1]
Beta-galactosidase (bgaB) DME Info MIC = 0.4 microM [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.3 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 2.2 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.3 microM [1]
Glutamate racemase (MurI) DME Info MIC = 0.3 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 93 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 2.2 microM [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 0.3 microM [1]
NADPH-dependent nitroreductase (nfrA1) DME Info MIC = 16 microM [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.3 microM [1]
Nitroreductase (NTR) DME Info MIC = 0.4 microM [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.3 microM [1]
NADH dehydrogenase (nuoE) DME Info MIC = 0.3 microM [3]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 2.2 microM [1]
Glutamate racemase (MurI) DME Info MIC = 16 microM [1]
Retro-nitroreductase (rNR) DME Info MIC = 0.4 microM [2]
Tyramine oxidase (tynA) DME Info MIC = 0.3 microM [1]
Beta-glucuronidase (uidA) DME Info MIC = 0.3 microM [1]
Glutamate racemase (MurI) DME Info MIC = 16 microM [1]
General stress protein 14 (ywrO) DME Info MIC = 16 microM [1]
References
1 Molecular evolution of the Cecropin multigene family in Drosophilafunctional genes vspseudogenes. Genetics. 1998 Sep;150(1):157-71.
2 The immune response in Drosophila: pattern of cecropin expression and biological activity. EMBO J. 1990 Sep;9(9):2969-76.
3 The cecropin locus in Drosophila; a compact gene cluster involved in the response to infection. EMBO J. 1990 Jan;9(1):217-24.

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