General Information of Xenobiotics (ID: XEO03985)
Xenobiotics Name
Magainin-2
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Beta-lactamase (blaB) DME Info Citrobacter freundii [1], [2]
Beta-lactamase (blaB) DME Info Serratia marcescens [1], [2]
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Glycosyl hydrolase (glyH) DME Info Pseudomonas putida [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella variicola [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [1], [2]
Beta-lactamase (blaB) DME Info Enterobacter cloacae [1], [2]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [1], [2]
Cytidine deaminase (cdd) DME Info Escherichia coli [1], [2]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Citrobacter freundii [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
Beta-galactosidase (bgaB) DME Info Enterobacter cloacae [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [1], [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Serratia marcescens [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Nitroreductase (NTR) DME Info Enterobacter cloacae [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Citrobacter freundii [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [1], [2]
Nicotinate dehydrogenase (nicA) DME Info Pseudomonas putida [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Pseudomonas putida [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas putida [1], [2]
Retro-nitroreductase (rNR) DME Info Enterobacter cloacae [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Beta-lactamase (blaB) DME Info MIC = 30 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 100 ug/ml [1], [2]
Azoreductase (azoR) DME Info MIC = 5 ug/ml [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 5 ug/ml [1], [2]
Glycosyl hydrolase (glyH) DME Info MIC = 10 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 10 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 5 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 10 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 50 ug/ml [1], [2]
Metallo-beta-lactamase (blaM) DME Info MIC = 10 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 10 ug/ml [1], [2]
Cytidine deaminase (cdd) DME Info MIC = 10 ug/ml [1], [2]
Cytidine deaminase (cdd) DME Info MIC = 10 ug/ml [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 5 ug/ml [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 5 ug/ml [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 5 ug/ml [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 5 ug/ml [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 10 ug/ml [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 30 ug/ml [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 5 ug/ml [1], [2]
Beta-galactosidase (bgaB) DME Info MIC = 50 ug/ml [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 5 ug/ml [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 100 ug/ml [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 10 ug/ml [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 5 ug/ml [1], [2]
Methylthioribose kinase (mtnK) DME Info MIC = 10 ug/ml [1], [2]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info MIC = 10 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC = 5 ug/ml [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 100 ug/ml [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 100 ug/ml [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 5 ug/ml [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 50 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 5 ug/ml [1], [2]
Nitroreductase (NTR) DME Info MIC = 50 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 5 ug/ml [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 30 ug/ml [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 10 ug/ml [1], [2]
Nicotinate dehydrogenase (nicA) DME Info MIC = 10 ug/ml [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 5 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 10 ug/ml [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 100 ug/ml [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 10 ug/ml [1], [2]
Retro-nitroreductase (rNR) DME Info MIC = 50 ug/ml [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 5 ug/ml [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 5 ug/ml [1], [2]
References
1 Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci U S A. 1987 Aug;84(15):5449-53.
2 Two-dimensional 1H NMR experiments show that the 23-residue magainin antibiotic peptide is an alpha-helix in dodecylphosphocholine micelles, sodium dodecylsulfate micelles, and trifluoroethanol/water solution. J Biomol NMR. 1997 Feb;9(2):127-35.

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