Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO02731)
Xenobiotics Name
Cathelicidin
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=16198951"></iframe>
3D MOL 2D MOL
PubChem CID
16198951
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aminoglycoside N-acetyltransferase (aacC2) DME Info Acinetobacter baumannii [1]
Beta-lactamase (blaB) DME Info Serratia marcescens [2], [3]
Aminoglycoside O-phosphotransferase (aphA6) DME Info Acinetobacter baumannii [1]
Azoreductase (azoR) DME Info Escherichia coli [2], [3]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [2], [3]
Beta-lactamase (blaB) DME Info Escherichia coli [2], [3]
Beta-lactamase (blaB) DME Info Acinetobacter baumannii [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [2], [3]
Glycoside hydrolase (cscA) DME Info Escherichia coli [2], [3]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [2], [3]
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [2], [3]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [2], [3]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [2], [3]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [2], [3]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [2], [3]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [2], [3]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [2], [3]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [4]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [2], [3]
Glutamate racemase (MurI) DME Info Escherichia coli [2], [3]
Arylamine N-acetyltransferase (NAT) DME Info Serratia marcescens [2], [3]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [4]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [2], [3]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [4]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [2], [3]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [2], [3]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [2], [3]
Nicotinamidase (pncA) DME Info Acinetobacter baumannii [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [4]
Tyramine oxidase (tynA) DME Info Escherichia coli [2], [3]
Beta-glucuronidase (uidA) DME Info Escherichia coli [2], [3]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Beta-lactamase (blaB) DME Info MIC = 4 microM [2], [3]
Azoreductase (azoR) DME Info MIC = 1 microM [2], [3]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 1 microM [2], [3]
Beta-lactamase (blaB) DME Info MIC = 1 microM [2], [3]
Chloramphenicolase (chlR) DME Info MIC = 1 microM [2], [3]
Glycoside hydrolase (cscA) DME Info MIC = 1 microM [2], [3]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 1 microM [2], [3]
Cytochrome P450 102A1 (cyp102) DME Info MIC = 4 microM [2], [3]
Cytochrome P450 MEG (cyp106) DME Info MIC = 4 microM [2], [3]
Cytochrome P450 21A2 (cyp21) DME Info MIC = 4 microM [2], [3]
Cytochrome P450 BM3 (cypBM3) DME Info MIC = 4 microM [2], [3]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 1 microM [2], [3]
Glutamate decarboxylase (gadB) DME Info MIC = 1 microM [2], [3]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 1 microM [2], [3]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.63 microM [4]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 1 microM [2], [3]
Glutamate racemase (MurI) DME Info MIC = 1 microM [2], [3]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 4 microM [2], [3]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 0.63 microM [4]
N-ethylmaleimide reductase (nemA) DME Info MIC = 1 microM [2], [3]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 1.25 microM [4]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 1 microM [2], [3]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 1 microM [2], [3]
NADH dehydrogenase (nuoE) DME Info MIC = 1 microM [2], [3]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 0.63 microM [4]
Tyramine oxidase (tynA) DME Info MIC = 1 microM [2], [3]
Beta-glucuronidase (uidA) DME Info MIC = 1 microM [2], [3]
References
1 The human antimicrobial peptide LL-37 and its fragments possess both antimicrobial and antibiofilm activities against multidrug-resistant Acinetobacter baumannii. Peptides. 2013 Nov;49:131-7.
2 Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse. J Biol Chem. 1997 May 16;272(20):13088-93.
3 A novel murine cathelin-like protein expressed in bone marrow. FEBS Lett. 1996 Aug 5;391(1-2):5-8.
4 Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken. FEBS J. 2006 Jun;273(12):2581-93.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.