Interactions between Xenobiotics and DME (XEOTIC)
|
Amino Acid(s), Peptide(s) or Protein(s) |
Peptide |
Click to Show/Hide the Full List of Xenobiotics: 42 Xenobiotics
|
Acaloleptin-A1 |
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Inhibition |
XEOTIC ID |
XEO02117
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Acaloleptin-A1 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[1], [2] |
Acaloleptin-A2 |
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Inhibition |
XEOTIC ID |
XEO02118
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Acaloleptin-A2 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[1], [2] |
Acaloleptin-A3 |
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Inhibition |
XEOTIC ID |
XEO02119
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Acaloleptin-A3 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[1], [2] |
Acaloleptin-A4 |
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Inhibition |
XEOTIC ID |
XEO02120
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Acaloleptin-A4 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[1], [2] |
Acaloleptin-A5 |
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Inhibition |
XEOTIC ID |
XEO02121
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Acaloleptin-A5 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[1], [2] |
Andropin |
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Inhibition |
XEOTIC ID |
XEO02226
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Andropin inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 127 microM) |
[3] |
Antimicrobial protein AN5-1 |
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Inhibition |
XEOTIC ID |
XEO02298
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Antimicrobial protein AN5-1 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 32 ug/ml) |
[4] |
Bovine cathelicidin BMAP-34 |
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Inhibition |
XEOTIC ID |
XEO02466
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Bovine cathelicidin BMAP-34 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 1.5 microM) |
[5], [6] |
Bradykinin-potentiating BmK3 |
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Inhibition |
XEOTIC ID |
XEO02491
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Bradykinin-potentiating BmK3 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 68.2 microM) |
[7], [8] |
Cathelicidin |
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Inhibition |
XEOTIC ID |
XEO02731
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Cathelicidin inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 4 microM) |
[9], [10] |
Cathelicidin-5 |
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Inhibition |
XEOTIC ID |
XEO02739
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Cathelicidin-5 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 2 microM) |
[11], [12] |
Cathelicidin-6 |
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Inhibition |
XEOTIC ID |
XEO02740
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Cathelicidin-6 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 2 ug/ml) |
[11], [13] |
D-amino-acid pexiganan MSI-214 |
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Inhibition |
XEOTIC ID |
XEO03073
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
D-amino-acid pexiganan MSI-214 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 256 ug/ml) |
[14] |
Drosophila cecropin-A1/A2 |
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Inhibition |
XEOTIC ID |
XEO03225
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Drosophila cecropin-A1/A2 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 93 microM) |
[15] |
Gaegurin-2 |
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Inhibition |
XEOTIC ID |
XEO03437
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Gaegurin-2 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 200 ug/ml) |
[16] |
Gaegurin-3 |
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Inhibition |
XEOTIC ID |
XEO03438
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Gaegurin-3 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 200 ug/ml) |
[16] |
Gaegurin-4 |
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Inhibition |
XEOTIC ID |
XEO03439
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Gaegurin-4 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 200 ug/ml) |
[17] |
Gaegurin-6 |
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Inhibition |
XEOTIC ID |
XEO03441
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Gaegurin-6 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 200 ug/ml) |
[16] |
Hadrurin |
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Inhibition |
XEOTIC ID |
XEO03519
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Hadrurin inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[18] |
Hydramacin Hm-1 |
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Inhibition |
XEOTIC ID |
XEO03609
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Hydramacin Hm-1 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[19], [20] |
Immune protein P9 |
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Inhibition |
XEOTIC ID |
XEO02769
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Immune protein P9 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 2.2 microM) |
[21] |
Insect attacin-C |
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Inhibition |
XEOTIC ID |
XEO02333
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Insect attacin-C inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 200 microM) |
[22] |
Insect cecropin-A |
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Inhibition |
XEOTIC ID |
XEO02768
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Insect cecropin-A inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[21] |
Insect cecropin-D |
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Inhibition |
XEOTIC ID |
XEO02772
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Insect cecropin-D inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[21], [23] |
Insect defensin A |
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Inhibition |
XEOTIC ID |
XEO03116
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Insect defensin A inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 40 microM) |
[24] |
M-zodatoxin-Lt8c |
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Inhibition |
XEOTIC ID |
XEO04185
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
M-zodatoxin-Lt8c inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[25] |
Magainin-2 |
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Inhibition |
XEOTIC ID |
XEO03985
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Magainin-2 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 100 ug/ml) |
[26], [27] |
Mammal mBMAP28 |
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Inhibition |
XEOTIC ID |
XEO04039
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Mammal mBMAP28 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 4 microM) |
[11] |
Myeloid antimicrobial peptide BMAP-27 |
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Inhibition |
XEOTIC ID |
XEO04158
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Myeloid antimicrobial peptide BMAP-27 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 2 microM) |
[11] |
Myeloid antimicrobial peptide BMAP-28 |
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Inhibition |
XEOTIC ID |
XEO04159
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Myeloid antimicrobial peptide BMAP-28 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 2 microM) |
[11] |
Opistoporin-1 |
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Inhibition |
XEOTIC ID |
XEO04399
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Opistoporin-1 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC = 50 microM) |
[28] |
Piscidin Pis-1 |
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Inhibition |
XEOTIC ID |
XEO04612
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Piscidin Pis-1 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 20 microM) |
[29] |
Piscidin Pis-2 |
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Inhibition |
XEOTIC ID |
XEO04613
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Piscidin Pis-2 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 20 microM) |
[30] |
Pleurocidin |
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Inhibition |
XEOTIC ID |
XEO04640
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Pleurocidin inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens (MIC > 35.0 microM) |
[31] |
Ponericin G1 |
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Inhibition |
XEOTIC ID |
XEO04695
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Ponericin G1 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[32] |
Ponericin G3 |
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Inhibition |
XEOTIC ID |
XEO04696
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Ponericin G3 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[32] |
Ponericin-L2 |
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Inhibition |
XEOTIC ID |
XEO04699
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Ponericin-L2 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[32] |
Ponericin-W1 |
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Inhibition |
XEOTIC ID |
XEO04700
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Ponericin-W1 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[32] |
Ponericin-W3 |
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Inhibition |
XEOTIC ID |
XEO04701
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Ponericin-W3 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[32] |
Ponericin-W4 |
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Inhibition |
XEOTIC ID |
XEO04702
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Ponericin-W4 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[32] |
Ponericin-W5 |
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Inhibition |
XEOTIC ID |
XEO04703
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Ponericin-W5 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[32] |
Ponericin-W6 |
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Inhibition |
XEOTIC ID |
XEO04704
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Peptide |
DME Modulation |
Ponericin-W6 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[32] |
Health or Environmental Toxicant(s) |
Acute Toxic Substance |
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|
Oxyquinoline |
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Inhibition |
XEOTIC ID |
XEO01419
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Acute Toxic Substance |
DME Modulation |
Oxyquinoline inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[33] |
Natural Product(s), Extract(s) or Medicine(s) |
Bacterial Extract |
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|
Coral associated bacteria 23 |
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Inhibition |
XEOTIC ID |
XEO02912
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Bacterial Extract |
DME Modulation |
Coral associated bacteria 23 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[34] |
Coral associated bacteria 41 |
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Inhibition |
XEOTIC ID |
XEO02913
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Bacterial Extract |
DME Modulation |
Coral associated bacteria 41 inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[34] |
Natural Product |
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|
2,4-Di-tert-butylphenol |
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Inhibition |
XEOTIC ID |
XEO04557
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Natural Product |
DME Modulation |
2,4-Di-tert-butylphenol inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[35] |
Plant Extract |
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|
Burdock roots methanol extract |
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Inhibition |
XEOTIC ID |
XEO04086
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Plant Extract |
DME Modulation |
Burdock roots methanol extract inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[36] |
Capparis spinosa methanolic extract |
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Inhibition |
XEOTIC ID |
XEO04089
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Plant Extract |
DME Modulation |
Capparis spinosa methanolic extract inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[37] |
Hyptis suaveolens hexane extract |
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Inhibition |
XEOTIC ID |
XEO03552
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Plant Extract |
DME Modulation |
Hyptis suaveolens hexane extract inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[38] |
Piper betle ethyl acetate extract |
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Inhibition |
XEOTIC ID |
XEO03354
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Plant Extract |
DME Modulation |
Piper betle ethyl acetate extract inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[39] |
Sponge Extract |
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|
Aphrocallistes bocagei methanol extract |
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Inhibition |
XEOTIC ID |
XEO04081
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Sponge Extract |
DME Modulation |
Aphrocallistes bocagei methanol extract inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[40] |
Clathria atrasanguinea methanol extract |
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Inhibition |
XEOTIC ID |
XEO04082
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Sponge Extract |
DME Modulation |
Clathria atrasanguinea methanol extract inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[40] |
Haliclona megastoma methanol extract |
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Inhibition |
XEOTIC ID |
XEO04083
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Sponge Extract |
DME Modulation |
Haliclona megastoma methanol extract inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[40] |
Pharmaceutical Agent(s) |
Drug in Phase 3 Clinical Trial |
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|
Curcumin |
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Inhibition |
XEOTIC ID |
XEO00683
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Highest Clinical Status: Phase 3 |
DME Modulation |
Curcumin inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[41] |
Epigallocatechin gallate |
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Inhibition |
XEOTIC ID |
XEO00613
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Highest Clinical Status: Phase 3 |
DME Modulation |
Epigallocatechin gallate inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[42] |
Drug in Phase 2 Clinical Trial |
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|
Butane-1,4-diamine |
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Inhibition |
XEOTIC ID |
XEO02654
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Highest Clinical Status: Phase 2 |
DME Modulation |
Butane-1,4-diamine inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[33] |
Drug in Phase 1 Clinical Trial |
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|
Phenanthrene |
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Inhibition |
XEOTIC ID |
XEO00574
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Highest Clinical Status: Phase 1 |
DME Modulation |
Phenanthrene inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[38] |
Investigative Agent |
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|
Ethane-1,2-diamine |
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Inhibition |
XEOTIC ID |
XEO03340
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Investigative Agent |
DME Modulation |
Ethane-1,2-diamine inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[33] |
Undecanoic acid |
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Inhibition |
XEOTIC ID |
XEO05199
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Investigative Agent |
DME Modulation |
Undecanoic acid inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[38] |
Other Chemical Compound(s) or Element(s) |
Chemical Compound |
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|
1,8-Diaminooctane |
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Inhibition |
XEOTIC ID |
XEO04352
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Chemical Compound |
DME Modulation |
1,8-Diaminooctane inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[33] |
7-chloroquinolin-4-ol |
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Inhibition |
XEOTIC ID |
XEO02091
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Chemical Compound |
DME Modulation |
7-chloroquinolin-4-ol inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[33] |
N1-(7-chloroquinolin-4-yl)ethane-1,2-diamine |
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Inhibition |
XEOTIC ID |
XEO04208
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Chemical Compound |
DME Modulation |
N1-(7-chloroquinolin-4-yl)ethane-1,2-diamine inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Serratia marcescens |
[33] |
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