Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO02734) | ||||||
|---|---|---|---|---|---|---|
| Xenobiotics Name |
Fowlicidin-1
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| Xenobiotics Type |
Amino Acid(s), Peptide(s) or Protein(s)
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| Classification |
Peptide
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| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Beta-lactamase (blaB) | DME Info | Klebsiella variicola | [1] | |||
| Beta-lactamase (blaB) | DME Info | Salmonella enterica | [1] | |||
| Beta-lactamase (blaB) | DME Info | Klebsiella aerogenes | [1] | |||
| Metallo-beta-lactamase (blaM) | DME Info | Klebsiella pneumoniae | [1] | |||
| Beta-lactamase (blaB) | DME Info | Klebsiella pneumoniae | [1] | |||
| Cytidine deaminase (cdd) | DME Info | Escherichia coli | [1] | |||
| Cytidine deaminase (cdd) | DME Info | Klebsiella pneumoniae | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Klebsiella pneumoniae | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Salmonella enterica | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | Listeria monocytogenes | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | Klebsiella pneumoniae | [1] | |||
| Methylthioribose kinase (mtnK) | DME Info | Klebsiella pneumoniae | [1] | |||
| S-adenosylhomocysteine nucleosidase (mtnN) | DME Info | Klebsiella pneumoniae | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Pseudomonas aeruginosa | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | Staphylococcus aureus | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | Salmonella enterica | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | Salmonella enterica | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Klebsiella pneumoniae | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Xenobiotics-DME Activity Data | ||||||
| Xenobiotics-DME Activity Data | Beta-lactamase (blaB) | DME Info | MIC = 0.40 microM | [1] | ||
| Beta-lactamase (blaB) | DME Info | MIC = 0.40 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 0.40 microM | [1] | |||
| Metallo-beta-lactamase (blaM) | DME Info | MIC = 0.40 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 0.40 microM | [1] | |||
| Cytidine deaminase (cdd) | DME Info | MIC = 0.40 microM | [1] | |||
| Cytidine deaminase (cdd) | DME Info | MIC = 0.40 microM | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 0.40 microM | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 0.40 microM | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | MIC = 0.80 microM | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | MIC = 3.18 microM | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | MIC = 0.40 microM | [1] | |||
| Methylthioribose kinase (mtnK) | DME Info | MIC = 0.40 microM | [1] | |||
| S-adenosylhomocysteine nucleosidase (mtnN) | DME Info | MIC = 0.40 microM | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC = 3.18 microM | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | MIC = 0.40 microM | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | MIC = 0.40 microM | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | MIC = 0.40 microM | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC = 0.40 microM | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | MIC = 3.18 microM | [1] | |||
| References | ||||||
| 1 | Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken. FEBS J. 2006 Jun;273(12):2581-93. | |||||
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