Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03150)
Xenobiotics Name
Dermaseptin K4-S4(1-13)
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 9-3 microM [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 9-3 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 9-3 microM [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 9-3 microM [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 9-3 microM [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 9-3 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 9-3 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 9-3 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 9-3 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 9-3 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 9-3 microM [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 9-3 microM [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 4.5-1.5 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 9-3 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 9-3 microM [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 9-3 microM [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 9-3 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 9-3 microM [1], [2]
References
1 Consequences of N-acylation on structure and membrane binding properties of dermaseptin derivative K4-S4-(1-13). J Biol Chem. 2006 Apr 7;281(14):9432-8.
2 Effects of acyl versus aminoacyl conjugation on the properties of antimicrobial peptides. Antimicrob Agents Chemother. 2005 Jun;49(6):2412-20.

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