Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03588)
Xenobiotics Name
Human beta-defensin hBD-2
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
Azoreductase (azoR) DME Info Enterococcus faecalis [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Enterococcus faecalis [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [3]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [3]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [2]
Tyrosine decarboxylase (tdc) DME Info Enterococcus faecalis [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
VanA ligase (vanA) DME Info Enterococcus faecalis [1]
VanB ligase (vanB) DME Info Enterococcus faecalis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 62 ug/ml [1]
Azoreductase (azoR) DME Info MIC = 15 ug/ml [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 62 ug/ml [1]
Beta-lactamase (blaB) DME Info MIC = 62 ug/ml [1]
Chloramphenicolase (chlR) DME Info MIC = 62 ug/ml [1]
Glycoside hydrolase (cscA) DME Info MIC = 62 ug/ml [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 62 ug/ml [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 62 ug/ml [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 15 ug/ml [1]
Glutamate decarboxylase (gadB) DME Info MIC = 62 ug/ml [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 62 ug/ml [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 62 ug/ml [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 62 ug/ml [1]
Glutamate racemase (MurI) DME Info MIC = 62 ug/ml [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 62 ug/ml [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 62 ug/ml [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 62 ug/ml [3]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 62 ug/ml [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 62 ug/ml [1]
NADH dehydrogenase (nuoE) DME Info MIC = 62 ug/ml [3]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 62 ug/ml [2]
Tyrosine decarboxylase (tdc) DME Info MIC = 15 ug/ml [1]
Tyramine oxidase (tynA) DME Info MIC = 62 ug/ml [1]
Beta-glucuronidase (uidA) DME Info MIC = 62 ug/ml [1]
VanA ligase (vanA) DME Info MIC = 15 ug/ml [1]
VanB ligase (vanB) DME Info MIC = 15 ug/ml [1]
References
1 Arabidopsis thaliana plants expressing human beta-defensin-2 are more resistant to fungal attack: functional homology between plant and human defensins. Plant Cell Rep. 2007 Aug;26(8):1391-8.
2 A peptide antibiotic from human skin. Nature. 1997 Jun 26;387(6636):861.
3 The structure of human beta-defensin-2 shows evidence of higher order oligomerization. J Biol Chem. 2000 Oct 20;275(42):32911-8.

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