General Information of Xenobiotics (ID: XEO04178)
Xenobiotics Name
M-zodatoxin-Lt2a
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Saccharomyces cerevisiae [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Bacillus pumilus [1], [2]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 0.7 microM [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 0.7 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 0.7 microM [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 0.7 microM [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 0.7 microM [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 0.7 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.7 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 54 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 0.7 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.7 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 6.7 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.7 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 0.7 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 6.7 microM [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 0.7 microM [1], [2]
NADPH-dependent nitroreductase (nfrA1) DME Info MIC = 0.4 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.7 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.7 microM [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 0.7 microM [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 6.7 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 0.4 microM [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 0.7 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 0.7 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 0.4 microM [1], [2]
General stress protein 14 (ywrO) DME Info MIC = 0.4 microM [1], [2]
References
1 Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity. J Biol Chem. 2006 Jul 28;281(30):20983-92.
2 Spatial structure and activity mechanism of a novel spider antimicrobial peptide. Biochemistry. 2006 Sep 5;45(35):10759-67.

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