General Information of Xenobiotics (ID: XEO04573)
Xenobiotics Name
Phylloseptin PS-7
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [3]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 6 microM [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 6 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 6 microM [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 6 microM [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 6 microM [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 6 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 6 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 6 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 6 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 6 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 6 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 6 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 6 microM [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 6 microM [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 3.6 microM [3]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 6 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 6 microM [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 6 microM [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 6 microM [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 6 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 6 microM [1], [2]
References
1 Isolation and biochemical characterization of peptides presenting antimicrobial activity from the skin of Phyllomedusa hypochondrialis. Peptides. 2006 Dec;27(12):3092-9.
2 Elements of the granular gland peptidome and transcriptome persist in air-dried skin of the South American orange-legged leaf frog, Phyllomedusa hypocondrialis. Peptides. 2006 Sep;27(9):2129-36.
3 A combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea. Peptides. 2007 Jul;28(7):1331-43.

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