Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO05182) | ||||||
|---|---|---|---|---|---|---|
| Xenobiotics Name |
Ixosin-B peptide derivative TSG-10
|
|||||
| Xenobiotics Type |
Amino Acid(s), Peptide(s) or Protein(s)
|
|||||
| Classification |
Peptide
|
|||||
| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Azoreductase (azoR) | DME Info | Escherichia coli | [1] | |||
| L,D-carboxypeptidase A (ldcA) | DME Info | Escherichia coli | [1] | |||
| Beta-lactamase (blaB) | DME Info | Escherichia coli | [1] | |||
| Chloramphenicolase (chlR) | DME Info | Escherichia coli | [1] | |||
| Glycoside hydrolase (cscA) | DME Info | Escherichia coli | [1] | |||
| NADPH-dependent curcumin reductase (curA) | DME Info | Escherichia coli | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Escherichia coli | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | Escherichia coli | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | Escherichia coli | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | Escherichia coli | [1] | |||
| Glutamate racemase (MurI) | DME Info | Escherichia coli | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Pseudomonas aeruginosa | [1] | |||
| N-ethylmaleimide reductase (nemA) | DME Info | Escherichia coli | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | Staphylococcus aureus | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | Escherichia coli | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | Escherichia coli | [1] | |||
| NADH dehydrogenase (nuoE) | DME Info | Streptomyces griseus | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Tyramine oxidase (tynA) | DME Info | Escherichia coli | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | Escherichia coli | [1] | |||
| Xenobiotics-DME Activity Data | ||||||
| Xenobiotics-DME Activity Data | Azoreductase (azoR) | DME Info | MIC = 64 microM | [1] | ||
| L,D-carboxypeptidase A (ldcA) | DME Info | MIC = 64 microM | [1] | |||
| Beta-lactamase (blaB) | DME Info | MIC = 64 microM | [1] | |||
| Chloramphenicolase (chlR) | DME Info | MIC = 64 microM | [1] | |||
| Glycoside hydrolase (cscA) | DME Info | MIC = 64 microM | [1] | |||
| NADPH-dependent curcumin reductase (curA) | DME Info | MIC = 64 microM | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 64 microM | [1] | |||
| Glutamate decarboxylase (gadB) | DME Info | MIC = 64 microM | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | MIC = 64 microM | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | MIC > 100 microM | [1] | |||
| Molybdopterin-dependent enzyme (molD) | DME Info | MIC = 64 microM | [1] | |||
| Glutamate racemase (MurI) | DME Info | MIC = 64 microM | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC > 100 microM | [1] | |||
| N-ethylmaleimide reductase (nemA) | DME Info | MIC = 64 microM | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | MIC = 64 microM | [1] | |||
| Oxygen-insensitive NADPH nitroreductase A (nfsA) | DME Info | MIC = 64 microM | [1] | |||
| Oxygen-insensitive NADPH nitroreductase B (nfsB) | DME Info | MIC = 64 microM | [1] | |||
| NADH dehydrogenase (nuoE) | DME Info | MIC = 64 microM | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | MIC > 100 microM | [1] | |||
| Tyramine oxidase (tynA) | DME Info | MIC = 64 microM | [1] | |||
| Beta-glucuronidase (uidA) | DME Info | MIC = 64 microM | [1] | |||
| References | ||||||
| 1 | Structure-activity relationship of potent antimicrobial peptide analogs of Ixosin-B amide. Bioorg Med Chem Lett. 2013 May 15;23(10):2929-32. | |||||
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.