General Information of Drug-Metabolizing Enzyme (DME ID: DME0009)
DME Name Cytochrome P450 2D6 (CYP2D6), Homo sapiens DME Info
UniProt ID
CP2D6_HUMAN
EC Number    EC: 1.14.14.1     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
Oxygen paired donor oxidoreductase
Flavin/flavoprotein donor oxidoreductase
EC: 1.14.14.1
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Interactome
Interactions between Microbiome and DME (MICBIO)
      Bacteria: Actinobacteria
                  Bifidobacterium adolescentis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium adolescentis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bifidobacterium breve (actinobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium breve co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium breve co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium breve co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium breve co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bifidobacterium longum (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium longum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium longum co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                  Bifidobacterium ruminatum (actinobacteria) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Alprenolol Click to Show/Hide the Detail
                                 Drug ID DR0076   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium ruminatum co-metabolize the drug Alprenolol, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Bupropion Click to Show/Hide the Detail
                                 Drug ID DR0247   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium ruminatum co-metabolize the drug Bupropion, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium ruminatum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluvoxamine maleate Click to Show/Hide the Detail
                                 Drug ID DR0740   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium ruminatum co-metabolize the drug Fluvoxamine maleate, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Metoprolol tartrate Click to Show/Hide the Detail
                                 Drug ID DR1072   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium ruminatum co-metabolize the drug Metoprolol tartrate, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bifidobacterium ruminatum co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                  Collinsella aerofaciens (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Loxapine succinate Click to Show/Hide the Detail
                                 Drug ID DR0989   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Collinsella aerofaciens co-metabolize the drug Loxapine succinate, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                              Nefazodone Click to Show/Hide the Detail
                                 Drug ID DR1135   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Collinsella aerofaciens co-metabolize the drug Nefazodone, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                  Collinsella intestinalis (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Collinsella intestinalis co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Collinsella intestinalis co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Eggerthella lenta (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Dopamine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0532   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Eggerthella lenta co-metabolize the drug Dopamine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [13], [14]
                  Mycobacterium tuberculosis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Dextromethorphan hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0476   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Mycobacterium tuberculosis co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [16]
                  Nocardia farcinica (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Nocardia farcinica co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [18]
                  Streptomyces griseus (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Doxorubicin Click to Show/Hide the Detail
                                 Drug ID DR0546   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Streptomyces griseus co-metabolize the drug Doxorubicin, which can collectively affect efficacy, safety or bioavailability of this drug. [19], [20]
      Bacteria: Bacteroidetes
                  Alistipes indistinctus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Alistipes indistinctus co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Alistipes indistinctus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Alistipes indistinctus co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Alistipes indistinctus co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Alistipes indistinctus co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Alistipes indistinctus co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Alistipes indistinctus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides caccae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Nefazodone Click to Show/Hide the Detail
                                 Drug ID DR1135   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides caccae co-metabolize the drug Nefazodone, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides caccae co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides caccae co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tegaserod Click to Show/Hide the Detail
                                 Drug ID DR1541   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides caccae co-metabolize the drug Tegaserod, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                  Bacteroides cellulosilyticus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides cellulosilyticus co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides cellulosilyticus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides coprophilus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides coprophilus co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Clonidine Click to Show/Hide the Detail
                                 Drug ID DR0352   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides coprophilus co-metabolize the drug Clonidine, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides coprophilus co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Galantamine hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0761   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides coprophilus co-metabolize the drug Galantamine hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides coprophilus co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Olanzapine Click to Show/Hide the Detail
                                 Drug ID DR1186   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides coprophilus co-metabolize the drug Olanzapine, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides coprophilus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides dorei (CFB bacteria) Click to Show/Hide the Full List of Drugs:      12 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Clonidine Click to Show/Hide the Detail
                                 Drug ID DR0352   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Clonidine, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides dorei co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides eggerthii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides eggerthii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides eggerthii co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides eggerthii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides eggerthii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides eggerthii co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides eggerthii co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides finegoldii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides finegoldii co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                  Bacteroides fragilis (CFB bacteria) Click to Show/Hide the Full List of Drugs:      16 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Clonidine Click to Show/Hide the Detail
                                 Drug ID DR0352   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Clonidine, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Galantamine hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0761   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Galantamine hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Lofexidine Click to Show/Hide the Detail
                                 Drug ID DR0967   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Lofexidine, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Metoprolol tartrate Click to Show/Hide the Detail
                                 Drug ID DR1072   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Metoprolol tartrate, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Olanzapine Click to Show/Hide the Detail
                                 Drug ID DR1186   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Olanzapine, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Sotalol Click to Show/Hide the Detail
                                 Drug ID DR1501   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Sotalol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides fragilis co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides intestinalis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides intestinalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides intestinalis co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides intestinalis co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides ovatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        9 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Clonidine Click to Show/Hide the Detail
                                 Drug ID DR0352   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Clonidine, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Galantamine hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0761   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Galantamine hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Sotalol Click to Show/Hide the Detail
                                 Drug ID DR1501   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Sotalol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides ovatus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides sartorii (CFB bacteria) Click to Show/Hide the Full List of Drugs:      16 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Clonidine Click to Show/Hide the Detail
                                 Drug ID DR0352   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Clonidine, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Galantamine hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0761   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Galantamine hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Nicergoline Click to Show/Hide the Detail
                                 Drug ID DR1145   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Nicergoline, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Penbutolol Click to Show/Hide the Detail
                                 Drug ID DR1249   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Penbutolol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Sotalol Click to Show/Hide the Detail
                                 Drug ID DR1501   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Sotalol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides sartorii co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides stercoris (CFB bacteria) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Clonidine Click to Show/Hide the Detail
                                 Drug ID DR0352   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides stercoris co-metabolize the drug Clonidine, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides stercoris co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides stercoris co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides stercoris co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides stercoris co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides stercoris co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides thetaiotaomicron (CFB bacteria) Click to Show/Hide the Full List of Drugs:      10 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Clonidine Click to Show/Hide the Detail
                                 Drug ID DR0352   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Clonidine, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Galantamine hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0761   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Galantamine hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Sotalol Click to Show/Hide the Detail
                                 Drug ID DR1501   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Sotalol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides thetaiotaomicron co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides uniformis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides uniformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides uniformis co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides uniformis co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides vulgatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:      10 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Imatinib mesylate Click to Show/Hide the Detail
                                 Drug ID DR0858   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Imatinib mesylate, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Penbutolol Click to Show/Hide the Detail
                                 Drug ID DR1249   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Penbutolol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides vulgatus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Bacteroides xylanisolvens (CFB bacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides xylanisolvens co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides xylanisolvens co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides xylanisolvens co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides xylanisolvens co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides xylanisolvens co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides xylanisolvens co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides xylanisolvens co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides xylanisolvens co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Odoribacter splanchnicus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        9 Drugs Metabolized
                              Clonidine Click to Show/Hide the Detail
                                 Drug ID DR0352   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Clonidine, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Olanzapine Click to Show/Hide the Detail
                                 Drug ID DR1186   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Olanzapine, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Odoribacter splanchnicus co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Parabacteroides distasonis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        9 Drugs Metabolized
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Nicergoline Click to Show/Hide the Detail
                                 Drug ID DR1145   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Nicergoline, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides distasonis co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Parabacteroides johnsonii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides johnsonii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides johnsonii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides johnsonii co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides johnsonii co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides johnsonii co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Parabacteroides merdae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides merdae co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides merdae co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides merdae co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Parabacteroides merdae co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Prevotella copri (CFB bacteria) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Prevotella copri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Prevotella copri co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Prevotella copri co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Sotalol Click to Show/Hide the Detail
                                 Drug ID DR1501   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Prevotella copri co-metabolize the drug Sotalol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Prevotella copri co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
      Bacteria: Firmicutes
                  Anaerobutyricum hallii (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerobutyricum hallii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerobutyricum hallii co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerobutyricum hallii co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Anaerococcus hydrogenalis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerococcus hydrogenalis co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerococcus hydrogenalis co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Anaerostipes hadrus (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerostipes hadrus co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Imatinib mesylate Click to Show/Hide the Detail
                                 Drug ID DR0858   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerostipes hadrus co-metabolize the drug Imatinib mesylate, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                  Anaerotruncus colihominis (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerotruncus colihominis co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Pimozide Click to Show/Hide the Detail
                                 Drug ID DR1291   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerotruncus colihominis co-metabolize the drug Pimozide, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Anaerotruncus colihominis co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bacillus megaterium (firmicutes) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus megaterium co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [39], [40]
                              Buspirone Click to Show/Hide the Detail
                                 Drug ID DR0248   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus megaterium co-metabolize the drug Buspirone, which can collectively affect efficacy, safety or bioavailability of this drug. [41], [40], [42]
                              CCRIS-9277 Click to Show/Hide the Detail
                                 Drug ID DR1089   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus megaterium co-metabolize the drug CCRIS-9277, which can collectively affect efficacy, safety or bioavailability of this drug. [43], [40]
                              Chlorzoxazone Click to Show/Hide the Detail
                                 Drug ID DR0312   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus megaterium co-metabolize the drug Chlorzoxazone, which can collectively affect efficacy, safety or bioavailability of this drug. [44], [45], [40]
                              Dextromethorphan hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0476   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus megaterium co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [15], [40]
                              Nifedipine Click to Show/Hide the Detail
                                 Drug ID DR1152   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus megaterium co-metabolize the drug Nifedipine, which can collectively affect efficacy, safety or bioavailability of this drug. [46], [45], [40]
                              Progesterone Click to Show/Hide the Detail
                                 Drug ID DR1346   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus megaterium co-metabolize the drug Progesterone, which can collectively affect efficacy, safety or bioavailability of this drug. [47], [42]
                              Propranolol hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1367   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus megaterium co-metabolize the drug Propranolol hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [48], [42]
                  Bacillus subtilis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Nitrofural Click to Show/Hide the Detail
                                 Drug ID DR1168   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacillus subtilis co-metabolize the drug Nitrofural, which can collectively affect efficacy, safety or bioavailability of this drug. [49], [50], [51]
                  Bacteroides pectinophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides pectinophilus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Bacteroides pectinophilus co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                  Blautia hansenii (firmicutes) Click to Show/Hide the Full List of Drugs:      15 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Cyclobenzaprine Click to Show/Hide the Detail
                                 Drug ID DR0390   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Cyclobenzaprine, which can collectively affect efficacy, safety or bioavailability of this drug. [52], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Fluvoxamine maleate Click to Show/Hide the Detail
                                 Drug ID DR0740   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Fluvoxamine maleate, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Nevirapine Click to Show/Hide the Detail
                                 Drug ID DR1142   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Nevirapine, which can collectively affect efficacy, safety or bioavailability of this drug. [53], [2]
                              Nicergoline Click to Show/Hide the Detail
                                 Drug ID DR1145   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Nicergoline, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia hansenii co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                  Blautia luti (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia luti co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Blautia luti co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Clostridioides difficile (firmicutes) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridioides difficile co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [39], [54]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridioides difficile co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Nicergoline Click to Show/Hide the Detail
                                 Drug ID DR1145   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridioides difficile co-metabolize the drug Nicergoline, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridioides difficile co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridioides difficile co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                  Clostridium botulinum (firmicutes) Click to Show/Hide the Full List of Drugs:      17 Drugs Metabolized
                              Cyclobenzaprine Click to Show/Hide the Detail
                                 Drug ID DR0390   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Cyclobenzaprine, which can collectively affect efficacy, safety or bioavailability of this drug. [52], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [30], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluvoxamine maleate Click to Show/Hide the Detail
                                 Drug ID DR0740   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Fluvoxamine maleate, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Metamfetamine Click to Show/Hide the Detail
                                 Drug ID DR1036   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Metamfetamine, which can collectively affect efficacy, safety or bioavailability of this drug. [55], [56]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Nevirapine Click to Show/Hide the Detail
                                 Drug ID DR1142   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Nevirapine, which can collectively affect efficacy, safety or bioavailability of this drug. [53], [2]
                              Nicergoline Click to Show/Hide the Detail
                                 Drug ID DR1145   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Nicergoline, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Paroxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1245   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Paroxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [57], [2]
                              Penbutolol Click to Show/Hide the Detail
                                 Drug ID DR1249   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Penbutolol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Pimozide Click to Show/Hide the Detail
                                 Drug ID DR1291   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Pimozide, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium botulinum co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                  Clostridium scindens (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium scindens co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium scindens co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Clostridium spiroforme (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium spiroforme co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Clostridium sporogenes (firmicutes) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium sporogenes co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Celecoxib Click to Show/Hide the Detail
                                 Drug ID DR0286   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium sporogenes co-metabolize the drug Celecoxib, which can collectively affect efficacy, safety or bioavailability of this drug. [58], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium sporogenes co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium sporogenes co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium sporogenes co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium sporogenes co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Vilazodone hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1687   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium sporogenes co-metabolize the drug Vilazodone hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [23], [2]
                  Clostridium symbiosum (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium symbiosum co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Clostridium symbiosum co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Coprococcus comes (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Coprococcus comes co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Coprococcus comes co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Dorea formicigenerans (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Dorea formicigenerans co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterocloster asparagiformis (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterocloster asparagiformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Nefazodone Click to Show/Hide the Detail
                                 Drug ID DR1135   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterocloster asparagiformis co-metabolize the drug Nefazodone, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterocloster asparagiformis co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterocloster asparagiformis co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Enterocloster bolteae (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterocloster bolteae co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Pimozide Click to Show/Hide the Detail
                                 Drug ID DR1291   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterocloster bolteae co-metabolize the drug Pimozide, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterocloster bolteae co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Enterococcus casseliflavus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Nitrofural Click to Show/Hide the Detail
                                 Drug ID DR1168   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterococcus casseliflavus co-metabolize the drug Nitrofural, which can collectively affect efficacy, safety or bioavailability of this drug. [49], [59]
                  Enterococcus faecalis (firmicutes) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterococcus faecalis co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [39], [54]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterococcus faecalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Levodopa Click to Show/Hide the Detail
                                 Drug ID DR0939   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterococcus faecalis co-metabolize the drug Levodopa, which can collectively affect efficacy, safety or bioavailability of this drug. [60], [14], [61]
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterococcus faecalis co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterococcus faecalis co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Enterococcus gallinarum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Nitrofural Click to Show/Hide the Detail
                                 Drug ID DR1168   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterococcus gallinarum co-metabolize the drug Nitrofural, which can collectively affect efficacy, safety or bioavailability of this drug. [49], [59]
                  Enterococcus malodoratus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metamfetamine Click to Show/Hide the Detail
                                 Drug ID DR1036   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterococcus malodoratus co-metabolize the drug Metamfetamine, which can collectively affect efficacy, safety or bioavailability of this drug. [55], [56]
                  Erysipelatoclostridium ramosum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Erysipelatoclostridium ramosum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Eubacterium rectale (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Eubacterium rectale co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Eubacterium rectale co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Eubacterium rectale co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Eubacterium ventriosum (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Eubacterium ventriosum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Eubacterium ventriosum co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                  Holdemanella biformis (firmicutes) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Holdemanella biformis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Celecoxib Click to Show/Hide the Detail
                                 Drug ID DR0286   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Holdemanella biformis co-metabolize the drug Celecoxib, which can collectively affect efficacy, safety or bioavailability of this drug. [58], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Holdemanella biformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Holdemanella biformis co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Penbutolol Click to Show/Hide the Detail
                                 Drug ID DR1249   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Holdemanella biformis co-metabolize the drug Penbutolol, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Holdemanella biformis co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Hungatella hathewayi (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Ranitidine Click to Show/Hide the Detail
                                 Drug ID DR1393   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Hungatella hathewayi co-metabolize the drug Ranitidine, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Hungatella hathewayi co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Lactobacillus acetotolerans (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metamfetamine Click to Show/Hide the Detail
                                 Drug ID DR1036   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Lactobacillus acetotolerans co-metabolize the drug Metamfetamine, which can collectively affect efficacy, safety or bioavailability of this drug. [55], [56]
                  Lactobacillus brevis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Levodopa Click to Show/Hide the Detail
                                 Drug ID DR0939   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Lactobacillus brevis co-metabolize the drug Levodopa, which can collectively affect efficacy, safety or bioavailability of this drug. [60], [61]
                  Lactobacillus reuteri (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Lactobacillus reuteri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Marvinbryantia formatexigens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Marvinbryantia formatexigens co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Roseburia intestinalis (firmicutes) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Roseburia intestinalis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Roseburia intestinalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Roseburia intestinalis co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Roseburia intestinalis co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Roseburia intestinalis co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Roseburia intestinalis co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Ruminococcus gnavus (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Ruminococcus gnavus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Ruminococcus gnavus co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Ruminococcus lactaris (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Ruminococcus lactaris co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Ruminococcus lactaris co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Ruminococcus lactaris co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Ruminococcus torques (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Ruminococcus torques co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Staphylococcus aureus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Nitrofural Click to Show/Hide the Detail
                                 Drug ID DR1168   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Staphylococcus aureus co-metabolize the drug Nitrofural, which can collectively affect efficacy, safety or bioavailability of this drug. [49], [62], [63]
                  Subdoligranulum variabile (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Subdoligranulum variabile co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Subdoligranulum variabile co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Subdoligranulum variabile co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Subdoligranulum variabile co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
      Bacteria: Lentisphaerae
                  Victivallis vadensis (PVC bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Victivallis vadensis co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [21], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Victivallis vadensis co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
      Bacteria: Proteobacteria
                  Acidovorax ebreus (beta-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Cefalexin Click to Show/Hide the Detail
                                 Drug ID DR0284   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Acidovorax ebreus co-metabolize the drug Cefalexin, which can collectively affect efficacy, safety or bioavailability of this drug. [64], [65]
                  Citrobacter freundii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Citrobacter freundii co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [39], [54]
                  Enterobacter cancerogenus (enterobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterobacter cancerogenus co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterobacter cancerogenus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Paliperidone Click to Show/Hide the Detail
                                 Drug ID DR1230   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterobacter cancerogenus co-metabolize the drug Paliperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Risperidone Click to Show/Hide the Detail
                                 Drug ID DR1428   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Enterobacter cancerogenus co-metabolize the drug Risperidone, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Escherichia coli (enterobacteria) Click to Show/Hide the Full List of Drugs:      13 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [39], [54]
                              Amphetamine Click to Show/Hide the Detail
                                 Drug ID DR0106   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Amphetamine, which can collectively affect efficacy, safety or bioavailability of this drug. [66], [67]
                              Bupropion Click to Show/Hide the Detail
                                 Drug ID DR0247   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Bupropion, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Doxorubicin Click to Show/Hide the Detail
                                 Drug ID DR0546   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Doxorubicin, which can collectively affect efficacy, safety or bioavailability of this drug. [19], [68]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Fluphenazine decanoate Click to Show/Hide the Detail
                                 Drug ID DR0722   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Fluphenazine decanoate, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [69]
                              Nicergoline Click to Show/Hide the Detail
                                 Drug ID DR1145   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Nicergoline, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Nitrofural Click to Show/Hide the Detail
                                 Drug ID DR1168   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Nitrofural, which can collectively affect efficacy, safety or bioavailability of this drug. [49], [70], [71]
                              Ritonavir Click to Show/Hide the Detail
                                 Drug ID DR1430   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Ritonavir, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Escherichia coli co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                  Helicobacter pylori (epsilon-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Levodopa Click to Show/Hide the Detail
                                 Drug ID DR0939   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Helicobacter pylori co-metabolize the drug Levodopa, which can collectively affect efficacy, safety or bioavailability of this drug. [60], [72]
                  Klebsiella pneumoniae (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Doxorubicin Click to Show/Hide the Detail
                                 Drug ID DR0546   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Klebsiella pneumoniae co-metabolize the drug Doxorubicin, which can collectively affect efficacy, safety or bioavailability of this drug. [19], [68]
                  Proteus penneri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Proteus penneri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Providencia alcalifaciens (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Providencia alcalifaciens co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                  Providencia rettgeri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Loperamide hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0974   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Providencia rettgeri co-metabolize the drug Loperamide hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [2]
                  Providencia stuartii (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Providencia stuartii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Providencia stuartii co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                  Pseudomonas putida (gamma-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Nicotine Click to Show/Hide the Detail
                                 Drug ID DR1148   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Pseudomonas putida co-metabolize the drug Nicotine, which can collectively affect efficacy, safety or bioavailability of this drug. [73], [74]
                  Raoultella planticola (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Doxorubicin Click to Show/Hide the Detail
                                 Drug ID DR0546   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Raoultella planticola co-metabolize the drug Doxorubicin, which can collectively affect efficacy, safety or bioavailability of this drug. [19], [68]
                  Salmonella enterica (enterobacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Salmonella enterica co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Nicergoline Click to Show/Hide the Detail
                                 Drug ID DR1145   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Salmonella enterica co-metabolize the drug Nicergoline, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Roxatidine Click to Show/Hide the Detail
                                 Drug ID DR1447   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Salmonella enterica co-metabolize the drug Roxatidine, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
      Bacteria: Verrucomicrobia
                  Akkermansia muciniphila (verrucomicrobiae) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Pimozide Click to Show/Hide the Detail
                                 Drug ID DR1291   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Akkermansia muciniphila co-metabolize the drug Pimozide, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
      Fungi: Ascomycota
                  Saccharomyces cerevisiae (ascomycota) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) metabolizes the drug Acetaminophen, and Saccharomyces cerevisiae further metabolizes its metabolite (1-Phenyl-1,2-propanedione), which can indirectly affect efficacy, safety or bioavailability of this drug. [39], [54]
      Archaea: Euryarchaeota
                  Methanobrevibacter oralis (methanobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Methanobrevibacter oralis co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [75]
                  Methanobrevibacter smithii (methanobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Methanobrevibacter smithii co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [75]
                  Methanomassiliicoccus luminyensis (thermoplasmata) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Methanomassiliicoccus luminyensis co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [75]
                  Methanosphaera stadtmanae (methanobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2D6 (CYP2D6) and Methanosphaera stadtmanae co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [75]
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