General Information of Drug-Metabolizing Enzyme (DME ID: DME0019)
DME Name Cytochrome P450 2C9 (CYP2C9), Homo sapiens DME Info
UniProt ID
CP2C9_HUMAN
EC Number    EC: 1.14.14.1     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
Oxygen paired donor oxidoreductase
Flavin/flavoprotein donor oxidoreductase
EC: 1.14.14.1
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Interactome
Interactions between Microbiome and DME (MICBIO)
      Bacteria: Actinobacteria
                  Bifidobacterium adolescentis (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium adolescentis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium adolescentis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bifidobacterium breve (actinobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Benzbromarone Click to Show/Hide the Detail
                                 Drug ID DR0193   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium breve co-metabolize the drug Benzbromarone, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium breve co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium breve co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium breve co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bifidobacterium longum (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium longum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium longum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bifidobacterium ruminatum (actinobacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Bupropion Click to Show/Hide the Detail
                                 Drug ID DR0247   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium ruminatum co-metabolize the drug Bupropion, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium ruminatum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium ruminatum co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium ruminatum co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium ruminatum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium ruminatum co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bifidobacterium ruminatum co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Collinsella aerofaciens (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Pitavastatin calcium Click to Show/Hide the Detail
                                 Drug ID DR1306   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Collinsella aerofaciens co-metabolize the drug Pitavastatin calcium, which can collectively affect efficacy, safety or bioavailability of this drug. [10], [2]
                              Zidovudine Click to Show/Hide the Detail
                                 Drug ID DR1729   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Collinsella aerofaciens co-metabolize the drug Zidovudine, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                  Collinsella intestinalis (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Collinsella intestinalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Collinsella intestinalis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Eggerthella lenta (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Dopamine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0532   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Eggerthella lenta co-metabolize the drug Dopamine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [12], [13]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Eggerthella lenta co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Mycobacterium tuberculosis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Dextromethorphan hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0476   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Mycobacterium tuberculosis co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [15]
                  Nocardia farcinica (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Nocardia farcinica co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [16]
                  Streptomyces avermitilis (actinobacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Coumarin Click to Show/Hide the Detail
                                 Drug ID DR0386   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Streptomyces avermitilis co-metabolize the drug Coumarin, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [18], [19]
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Streptomyces avermitilis co-metabolize the drug Diclofenac sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [18], [21]
                              Testosterone cypionate Click to Show/Hide the Detail
                                 Drug ID DR1564   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Streptomyces avermitilis co-metabolize the drug Testosterone cypionate, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [23], [18]
      Bacteria: Bacteroidetes
                  Alistipes indistinctus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Cyclophosphamide Click to Show/Hide the Detail
                                 Drug ID DR0391   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Alistipes indistinctus co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Alistipes indistinctus co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Alistipes indistinctus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Alistipes indistinctus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides caccae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides caccae co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bacteroides cellulosilyticus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides cellulosilyticus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides cellulosilyticus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides cellulosilyticus co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Bacteroides coprophilus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides coprophilus co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides coprophilus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides coprophilus co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides coprophilus co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides coprophilus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides coprophilus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides coprophilus co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Bacteroides dorei (CFB bacteria) Click to Show/Hide the Full List of Drugs:      20 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Diclofenac sodium, and Bacteroides dorei further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [20], [30]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides dorei co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Bacteroides eggerthii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides eggerthii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides eggerthii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides eggerthii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides eggerthii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides eggerthii co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Bacteroides finegoldii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides finegoldii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides fragilis (CFB bacteria) Click to Show/Hide the Full List of Drugs:      23 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Cyclophosphamide Click to Show/Hide the Detail
                                 Drug ID DR0391   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [39], [40]
                              Naftopidil Click to Show/Hide the Detail
                                 Drug ID DR1124   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Naftopidil, which can collectively affect efficacy, safety or bioavailability of this drug. [41], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Rosuvastatin Click to Show/Hide the Detail
                                 Drug ID DR1445   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Rosuvastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [43], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Tranilast Click to Show/Hide the Detail
                                 Drug ID DR1628   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Tranilast, which can collectively affect efficacy, safety or bioavailability of this drug. [44], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Warfarin sodium Click to Show/Hide the Detail
                                 Drug ID DR1717   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides fragilis co-metabolize the drug Warfarin sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                  Bacteroides intestinalis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides intestinalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides intestinalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides intestinalis co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides intestinalis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bacteroides oleiciplenus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides oleiciplenus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [45]
                  Bacteroides ovatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:      10 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides ovatus co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                  Bacteroides sartorii (CFB bacteria) Click to Show/Hide the Full List of Drugs:      19 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides sartorii co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Bacteroides stercoris (CFB bacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides stercoris co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides stercoris co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides stercoris co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides stercoris co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides stercoris co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides stercoris co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides stercoris co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides stercoris co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                  Bacteroides thetaiotaomicron (CFB bacteria) Click to Show/Hide the Full List of Drugs:      17 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Tranilast Click to Show/Hide the Detail
                                 Drug ID DR1628   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Tranilast, which can collectively affect efficacy, safety or bioavailability of this drug. [44], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides thetaiotaomicron co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Bacteroides uniformis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides uniformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides uniformis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides vulgatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:      19 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Imatinib mesylate Click to Show/Hide the Detail
                                 Drug ID DR0858   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Imatinib mesylate, which can collectively affect efficacy, safety or bioavailability of this drug. [46], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Indomethacin, and Bacteroides vulgatus further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [5], [47]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Venlafaxine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1679   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Venlafaxine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [35], [2]
                              Verapamil hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1681   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Verapamil hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                              Warfarin sodium Click to Show/Hide the Detail
                                 Drug ID DR1717   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides vulgatus co-metabolize the drug Warfarin sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [2]
                  Bacteroides xylanisolvens (CFB bacteria) Click to Show/Hide the Full List of Drugs:      17 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides xylanisolvens co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Odoribacter splanchnicus (CFB bacteria) Click to Show/Hide the Full List of Drugs:      17 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Odoribacter splanchnicus co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Parabacteroides distasonis (CFB bacteria) Click to Show/Hide the Full List of Drugs:      12 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Gliclazide Click to Show/Hide the Detail
                                 Drug ID DR0776   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Gliclazide, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [33], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
                              Voriconazole Click to Show/Hide the Detail
                                 Drug ID DR1709   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides distasonis co-metabolize the drug Voriconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [36], [2]
                  Parabacteroides johnsonii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        9 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Estrone sulfate Click to Show/Hide the Detail
                                 Drug ID DR0650   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Estrone sulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [48]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides johnsonii co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Parabacteroides merdae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides merdae co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides merdae co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides merdae co-metabolize the drug Indomethacin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides merdae co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides merdae co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides merdae co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Parabacteroides merdae co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Prevotella buccae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Estrone sulfate Click to Show/Hide the Detail
                                 Drug ID DR0650   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Prevotella buccae co-metabolize the drug Estrone sulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [17], [49], [50]
                  Prevotella copri (CFB bacteria) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Prevotella copri co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [51], [52]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Prevotella copri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Prevotella copri co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Prevotella copri co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Prevotella copri co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                              Valsartan Click to Show/Hide the Detail
                                 Drug ID DR1668   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Prevotella copri co-metabolize the drug Valsartan, which can collectively affect efficacy, safety or bioavailability of this drug. [34], [2]
      Bacteria: Firmicutes
                  Anaerobutyricum hallii (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerobutyricum hallii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerobutyricum hallii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerobutyricum hallii co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Anaerococcus hydrogenalis (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerococcus hydrogenalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerococcus hydrogenalis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Zidovudine Click to Show/Hide the Detail
                                 Drug ID DR1729   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerococcus hydrogenalis co-metabolize the drug Zidovudine, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [2]
                  Anaerostipes hadrus (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Imatinib mesylate Click to Show/Hide the Detail
                                 Drug ID DR0858   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerostipes hadrus co-metabolize the drug Imatinib mesylate, which can collectively affect efficacy, safety or bioavailability of this drug. [46], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerostipes hadrus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Anaerotruncus colihominis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerotruncus colihominis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Anaerotruncus colihominis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Bacillus megaterium (firmicutes) Click to Show/Hide the Full List of Drugs:        6 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacillus megaterium co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [53]
                              Dextromethorphan hydrobromide Click to Show/Hide the Detail
                                 Drug ID DR0476   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacillus megaterium co-metabolize the drug Dextromethorphan hydrobromide, which can collectively affect efficacy, safety or bioavailability of this drug. [14], [53]
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacillus megaterium co-metabolize the drug Diclofenac sodium, which can collectively affect efficacy, safety or bioavailability of this drug. [20], [54]
                              Mefenamic acid Click to Show/Hide the Detail
                                 Drug ID DR1014   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacillus megaterium co-metabolize the drug Mefenamic acid, which can collectively affect efficacy, safety or bioavailability of this drug. [55], [54]
                              Progesterone Click to Show/Hide the Detail
                                 Drug ID DR1346   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacillus megaterium co-metabolize the drug Progesterone, which can collectively affect efficacy, safety or bioavailability of this drug. [56], [57]
                              Testosterone cypionate Click to Show/Hide the Detail
                                 Drug ID DR1564   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacillus megaterium co-metabolize the drug Testosterone cypionate, which can collectively affect efficacy, safety or bioavailability of this drug. [22], [57], [58]
                  Bacteroides pectinophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides pectinophilus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides pectinophilus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides pectinophilus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Bacteroides pectinophilus co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Blautia hansenii (firmicutes) Click to Show/Hide the Full List of Drugs:      18 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Cyclophosphamide Click to Show/Hide the Detail
                                 Drug ID DR0391   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [38], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Irbesartan Click to Show/Hide the Detail
                                 Drug ID DR0879   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Irbesartan, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Nevirapine Click to Show/Hide the Detail
                                 Drug ID DR1142   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Nevirapine, which can collectively affect efficacy, safety or bioavailability of this drug. [59], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Rosuvastatin Click to Show/Hide the Detail
                                 Drug ID DR1445   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Rosuvastatin, which can collectively affect efficacy, safety or bioavailability of this drug. [43], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia hansenii co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Blautia luti (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Blautia luti co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridioides difficile (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridioides difficile co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [60]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridioides difficile co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridioides difficile co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridioides difficile co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Clostridium botulinum (firmicutes) Click to Show/Hide the Full List of Drugs:      13 Drugs Metabolized
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Doxazosin Click to Show/Hide the Detail
                                 Drug ID DR0542   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Doxazosin, which can collectively affect efficacy, safety or bioavailability of this drug. [31], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Fluconazole Click to Show/Hide the Detail
                                 Drug ID DR0704   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Fluconazole, which can collectively affect efficacy, safety or bioavailability of this drug. [32], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Nateglinide Click to Show/Hide the Detail
                                 Drug ID DR1132   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Nateglinide, which can collectively affect efficacy, safety or bioavailability of this drug. [37], [2]
                              Nevirapine Click to Show/Hide the Detail
                                 Drug ID DR1142   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Nevirapine, which can collectively affect efficacy, safety or bioavailability of this drug. [59], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Oxaprozin Click to Show/Hide the Detail
                                 Drug ID DR1212   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Oxaprozin, which can collectively affect efficacy, safety or bioavailability of this drug. [8], [2]
                              Sildenafil citrate Click to Show/Hide the Detail
                                 Drug ID DR1481   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Sildenafil citrate, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium botulinum co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Clostridium perfringens (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium perfringens co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [61]
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium perfringens co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [61]
                  Clostridium scindens (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium scindens co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium scindens co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Clostridium spiroforme (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium spiroforme co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium spiroforme co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Clostridium sporogenes (firmicutes) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium sporogenes co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Celecoxib Click to Show/Hide the Detail
                                 Drug ID DR0286   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium sporogenes co-metabolize the drug Celecoxib, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Clopidogrel bisulfate Click to Show/Hide the Detail
                                 Drug ID DR0355   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium sporogenes co-metabolize the drug Clopidogrel bisulfate, which can collectively affect efficacy, safety or bioavailability of this drug. [27], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium sporogenes co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium sporogenes co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium symbiosum (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium symbiosum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Clostridium symbiosum co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Coprococcus comes (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Coprococcus comes co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Coprococcus comes co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Dorea formicigenerans (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Dorea formicigenerans co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Dorea formicigenerans co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Dorea formicigenerans co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Enterocloster asparagiformis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterocloster asparagiformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterocloster asparagiformis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterocloster bolteae (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterocloster bolteae co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterocloster bolteae co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterocloster bolteae co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Enterococcus casseliflavus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterococcus casseliflavus co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [62]
                  Enterococcus faecalis (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterococcus faecalis co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [60]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterococcus faecalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterococcus faecalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterococcus gallinarum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterococcus gallinarum co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [62]
                  Erysipelatoclostridium ramosum (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Erysipelatoclostridium ramosum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Indomethacin, and Erysipelatoclostridium ramosum further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [5], [47]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Erysipelatoclostridium ramosum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Eubacterium rectale (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Eubacterium rectale co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Eubacterium rectale co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Eubacterium ventriosum (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Eubacterium ventriosum co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Eubacterium ventriosum co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Eubacterium ventriosum co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Faecalibacterium prausnitzii (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Diclofenac sodium, and Faecalibacterium prausnitzii further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [20], [30]
                  Holdemanella biformis (firmicutes) Click to Show/Hide the Full List of Drugs:        7 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Holdemanella biformis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Celecoxib Click to Show/Hide the Detail
                                 Drug ID DR0286   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Holdemanella biformis co-metabolize the drug Celecoxib, which can collectively affect efficacy, safety or bioavailability of this drug. [42], [2]
                              Cyclophosphamide Click to Show/Hide the Detail
                                 Drug ID DR0391   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Holdemanella biformis co-metabolize the drug Cyclophosphamide, which can collectively affect efficacy, safety or bioavailability of this drug. [24], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Holdemanella biformis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Glipizide Click to Show/Hide the Detail
                                 Drug ID DR0778   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Holdemanella biformis co-metabolize the drug Glipizide, which can collectively affect efficacy, safety or bioavailability of this drug. [29], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Holdemanella biformis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Tolazamide Click to Show/Hide the Detail
                                 Drug ID DR1611   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Holdemanella biformis co-metabolize the drug Tolazamide, which can collectively affect efficacy, safety or bioavailability of this drug. [9], [2]
                  Hungatella hathewayi (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Hungatella hathewayi co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Hungatella hathewayi co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Jeotgalicoccus psychrophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Jeotgalicoccus psychrophilus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [51], [52]
                  Lactobacillus reuteri (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Lactobacillus reuteri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Lactobacillus reuteri co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Lactobacillus rhamnosus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Diclofenac sodium, and Lactobacillus rhamnosus further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [20], [30]
                  Marvinbryantia formatexigens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Marvinbryantia formatexigens co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Roseburia hominis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Indomethacin, and Roseburia hominis further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [5], [47]
                  Roseburia intestinalis (firmicutes) Click to Show/Hide the Full List of Drugs:        5 Drugs Metabolized
                              Carvedilol Click to Show/Hide the Detail
                                 Drug ID DR0282   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Roseburia intestinalis co-metabolize the drug Carvedilol, which can collectively affect efficacy, safety or bioavailability of this drug. [26], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Roseburia intestinalis co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Indomethacin, and Roseburia intestinalis further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [5], [47]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Roseburia intestinalis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Roseburia intestinalis co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Ruminococcus albus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ruminococcus albus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [51], [52]
                  Ruminococcus gnavus (firmicutes) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Diclofenac sodium Click to Show/Hide the Detail
                                 Drug ID DR0488   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Diclofenac sodium, and Ruminococcus gnavus further metabolizes its metabolite (Diclofenac glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [20], [30]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ruminococcus gnavus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ruminococcus gnavus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ruminococcus gnavus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Ruminococcus lactaris (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ruminococcus lactaris co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ruminococcus lactaris co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ruminococcus lactaris co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Ruminococcus torques (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ruminococcus torques co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Subdoligranulum variabile (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Subdoligranulum variabile co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Subdoligranulum variabile co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Lentisphaerae
                  Victivallis vadensis (PVC bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Diltiazem hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0509   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Victivallis vadensis co-metabolize the drug Diltiazem hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [25], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Victivallis vadensis co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Proteobacteria
                  Citrobacter freundii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Citrobacter freundii co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [60]
                  Edwardsiella tarda (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Edwardsiella tarda co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Edwardsiella tarda co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Enterobacter cancerogenus (enterobacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterobacter cancerogenus co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterobacter cancerogenus co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterobacter cancerogenus co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterobacter cancerogenus co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Enterobacter cloacae (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Enterobacter cloacae co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [63]
                  Escherichia coli (enterobacteria) Click to Show/Hide the Full List of Drugs:        8 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Escherichia coli co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [60]
                              Bupropion Click to Show/Hide the Detail
                                 Drug ID DR0247   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Escherichia coli co-metabolize the drug Bupropion, which can collectively affect efficacy, safety or bioavailability of this drug. [6], [2]
                              Duloxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0554   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Escherichia coli co-metabolize the drug Duloxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [28], [2]
                              Flunitrazepam Click to Show/Hide the Detail
                                 Drug ID DR0712   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Escherichia coli co-metabolize the drug Flunitrazepam, which can collectively affect efficacy, safety or bioavailability of this drug. [64], [65]
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Escherichia coli co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Indomethacin Click to Show/Hide the Detail
                                 Drug ID DR0875   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Indomethacin, and Escherichia coli further metabolizes its metabolite (Indomethacin glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [5], [66]
                              Ketoprofen Click to Show/Hide the Detail
                                 Drug ID DR0907   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Ketoprofen, and Escherichia coli further metabolizes its metabolite (Ketoprofen glucuronide), which can indirectly affect efficacy, safety or bioavailability of this drug. [67], [68]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Escherichia coli co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Helicobacter apodemus (epsilon-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Aspirin Click to Show/Hide the Detail
                                 Drug ID DR1749   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Helicobacter apodemus co-metabolize the drug Aspirin, which can collectively affect efficacy, safety or bioavailability of this drug. [51], [52]
                  Proteus penneri (enterobacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Proteus penneri co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Proteus penneri co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Proteus penneri co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Providencia alcalifaciens (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Providencia alcalifaciens co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Providencia rettgeri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Providencia rettgeri co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Providencia stuartii (enterobacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Providencia stuartii co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Providencia stuartii co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Terbinafine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR1557   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Providencia stuartii co-metabolize the drug Terbinafine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [2]
                  Pseudomonas putida (gamma-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Nicotine Click to Show/Hide the Detail
                                 Drug ID DR1148   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Pseudomonas putida co-metabolize the drug Nicotine, which can collectively affect efficacy, safety or bioavailability of this drug. [69], [70]
                  Ralstonia solanacearum (beta-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              ANW-43703 Click to Show/Hide the Detail
                                 Drug ID DR1458   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Ralstonia solanacearum co-metabolize the drug ANW-43703, which can collectively affect efficacy, safety or bioavailability of this drug. [71], [72], [73]
                  Salmonella enterica (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Fluoxetine hydrochloride Click to Show/Hide the Detail
                                 Drug ID DR0720   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Salmonella enterica co-metabolize the drug Fluoxetine hydrochloride, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Salmonella enterica co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Salmonella typhimurium (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Niclosamide Click to Show/Hide the Detail
                                 Drug ID DR1146   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Salmonella typhimurium co-metabolize the drug Niclosamide, which can collectively affect efficacy, safety or bioavailability of this drug. [74], [75]
                  Shewanella oneidensis (gamma-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Sulfamethoxazole Click to Show/Hide the Detail
                                 Drug ID DR1511   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Shewanella oneidensis co-metabolize the drug Sulfamethoxazole, which can collectively affect efficacy, safety or bioavailability of this drug. [76], [77], [78]
                  Sphingomonas colocasiae (alpha-proteobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Ibuprofen Click to Show/Hide the Detail
                                 Drug ID DR0844   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Sphingomonas colocasiae co-metabolize the drug Ibuprofen, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [79]
      Bacteria: Synergistetes
                  Synergistetes bacterium (synergistetes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Sulfamethoxazole Click to Show/Hide the Detail
                                 Drug ID DR1511   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Synergistetes bacterium co-metabolize the drug Sulfamethoxazole, which can collectively affect efficacy, safety or bioavailability of this drug. [76], [80], [81]
      Bacteria: Verrucomicrobia
                  Akkermansia muciniphila (verrucomicrobiae) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Naftopidil Click to Show/Hide the Detail
                                 Drug ID DR1124   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Akkermansia muciniphila co-metabolize the drug Naftopidil, which can collectively affect efficacy, safety or bioavailability of this drug. [41], [2]
                              Omeprazole Click to Show/Hide the Detail
                                 Drug ID DR1196   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Akkermansia muciniphila co-metabolize the drug Omeprazole, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Fungi: Ascomycota
                  Saccharomyces cerevisiae (ascomycota) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) metabolizes the drug Acetaminophen, and Saccharomyces cerevisiae further metabolizes its metabolite (1-Phenyl-1,2-propanedione), which can indirectly affect efficacy, safety or bioavailability of this drug. [11], [60]
      Archaea: Euryarchaeota
                  Methanobrevibacter oralis (methanobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Methanobrevibacter oralis co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [82]
                  Methanobrevibacter smithii (methanobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Methanobrevibacter smithii co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [82]
                  Methanomassiliicoccus luminyensis (thermoplasmata) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Methanomassiliicoccus luminyensis co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [82]
                  Methanosphaera stadtmanae (methanobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Rifampicin Click to Show/Hide the Detail
                                 Drug ID DR1420   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Methanosphaera stadtmanae co-metabolize the drug Rifampicin, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [82]
      Amoebozoa: Evosea
                  Entamoeba histolytica (eukaryotes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Entamoeba histolytica co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [83]
      Metamonada: Fornicata
                  Giardia intestinalis (diplomonads) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Giardia intestinalis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [83]
      Metamonada: Parabasalia
                  Trichomonas vaginalis (trichomonads) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Metronidazole Click to Show/Hide the Detail
                                 Drug ID DR1073   Drug Info
                                 Interaction Mechanism Human Cytochrome P450 2C9 (CYP2C9) and Trichomonas vaginalis co-metabolize the drug Metronidazole, which can collectively affect efficacy, safety or bioavailability of this drug. [11], [83]
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