Details of Xenobiotics-DME Interaction (XEOTIC)

General Information of Drug-Metabolizing Enzyme (DME ID: DME1692)
DME Name Unclear metabolic mechanism (DME-unclear), Streptococcus mutans DME Info
Lineage    Species: Streptococcus mutans     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Streptococcaceae
Genus: Streptococcus
Species: Streptococcus mutans
Subspecies: Streptococcus mutans A12
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Amino Acid Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              L-cysteic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03813   XEOTIC Info Gene Form Protein
                                 Classification Amino Acid
                                 DME Modulation L-cysteic acid inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                  Peptide Click to Show/Hide the Full List of Xenobiotics:      16 Xenobiotics
                              2C-4 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01940   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation 2C-4 peptide inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [2]
                              Antimicrobial peptide lumbricin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02289   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide lumbricin-1 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans (MIC = 30 ug/ml) [3]
                              Buforin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02649   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Buforin-1 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans (MIC = 8 ug/ml) [4], [5]
                              Buforin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02650   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Buforin-2 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans (MIC = 2 ug/ml) [4], [5]
                              C16-33 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02670   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation C16-33 peptide inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [6]
                              Chrysophsin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02839   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Chrysophsin-1 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [7]
                              G2 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03433   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation G2 peptide inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [8]
                              Human MUC7 20-Mer Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04146   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Human MUC7 20-Mer inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [9]
                              L-amino-acid oxidase Casca LAO Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03796   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L-amino-acid oxidase Casca LAO inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [10]
                              Lumbrican Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03971   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lumbrican inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [3]
                              Lumbricin I(6-34) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03972   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Lumbricin I(6-34) inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans (MIC = 20 ug/ml) [3]
                              M8-33 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03978   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M8-33 peptide inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [6]
                              Misgurin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04117   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Misgurin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [11]
                              Mutacin-1140 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04155   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mutacin-1140 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [12]
                              Neurokinin A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04249   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Neurokinin A inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans (MIC > 500 ug/ml) [13]
                              Pleurocidin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04640   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [14]
      Health or Environmental Toxicant(s)
                  Environmental Pollutant Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Diphenyl disulphide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03191   XEOTIC Info Gene Form Protein
                                 Classification Environmental Pollutant
                                 DME Modulation Diphenyl disulphide inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
      Natural Product(s), Extract(s) or Medicine(s)
                  Bacterial Extract Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Streptococcus salivarius culture supernatant Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03009   XEOTIC Info Gene Form Protein
                                 Classification Bacterial Extract
                                 DME Modulation Streptococcus salivarius culture supernatant inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [15]
                  Fungal Extract Click to Show/Hide the Full List of Xenobiotics:        4 Xenobiotics
                              Hypsizygus marmoreus extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03372   XEOTIC Info Gene Form Protein
                                 Classification Fungal Extract
                                 DME Modulation Hypsizygus marmoreus extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [16]
                              Lentinula edodes extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03373   XEOTIC Info Gene Form Protein
                                 Classification Fungal Extract
                                 DME Modulation Lentinula edodes extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [16]
                              Pholiota nameko extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03374   XEOTIC Info Gene Form Protein
                                 Classification Fungal Extract
                                 DME Modulation Pholiota nameko extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [16]
                              Pleurotus eryngii extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03375   XEOTIC Info Gene Form Protein
                                 Classification Fungal Extract
                                 DME Modulation Pleurotus eryngii extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [16]
                  Natural Product Click to Show/Hide the Full List of Xenobiotics:      13 Xenobiotics
                              Aloe-emodin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01191   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Aloe-emodin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                              Carminic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02716   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Carminic acid inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                              Carolacton Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02722   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Carolacton inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [18]
                              Chrysophanic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01528   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Chrysophanic acid inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                              Clove oil Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01531   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Clove oil inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [19]
                              Erythritol Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03271   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Erythritol inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [20]
                              Gallic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01309   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Gallic acid inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [21]
                              Kaurenoic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03704   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Kaurenoic acid inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [22]
                              Limonene Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01559   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Limonene inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [23]
                              Octyl gallate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01408   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Octyl gallate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [24]
                              Pseudomonas quinolone signal Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04753   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Pseudomonas quinolone signal inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [25]
                              Sennidin A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04928   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Sennidin A inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                              Tyrosol Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05194   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Tyrosol inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [26]
                  Plant Extract Click to Show/Hide the Full List of Xenobiotics:        5 Xenobiotics
                              Salvadora persica acetone extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02124   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Salvadora persica acetone extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [27]
                              Salvadora persica aqueous extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02313   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Salvadora persica aqueous extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [27]
                              Salvadora persica chloroform extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02832   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Salvadora persica chloroform extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [27]
                              Salvadora persica ethanolic extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03350   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Salvadora persica ethanolic extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [27]
                              Salvadora persica methanolic extract Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04099   XEOTIC Info Gene Form Protein
                                 Classification Plant Extract
                                 DME Modulation Salvadora persica methanolic extract inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [27]
      Pharmaceutical Agent(s)
                  Approved/Marketed Drug Click to Show/Hide the Full List of Xenobiotics:        5 Xenobiotics
                              Cefixime Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02780   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Cefixime inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [28]
                              Chlorhexidine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02830   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Chlorhexidine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [9]
                              Reserpine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00222   XEOTIC Info Gene Form Protein
                                 Classification Drug Approved by US FDA
                                 DME Modulation Reserpine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [29]
                              Taurine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05032   XEOTIC Info Gene Form Protein
                                 Classification Drug Marketed but not Approved by US FDA
                                 DME Modulation Taurine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Thymol Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00487   XEOTIC Info Gene Form Protein
                                 Classification Drug Marketed but not Approved by US FDA
                                 DME Modulation Thymol inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [19]
                  Drug in Phase 3 Clinical Trial Click to Show/Hide the Full List of Xenobiotics:        4 Xenobiotics
                              Curcumin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00683   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 3
                                 DME Modulation Curcumin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [30]
                              Epigallocatechin gallate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00613   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 3
                                 DME Modulation Epigallocatechin gallate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [31]
                              SGX301 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00579   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 3
                                 DME Modulation SGX301 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                              Triclosan Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00560   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 3
                                 DME Modulation Triclosan inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [18]
                  Drug in Phase 1 Clinical Trial Click to Show/Hide the Full List of Xenobiotics:        3 Xenobiotics
                              Allicin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01976   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 1
                                 DME Modulation Allicin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Carvacrol Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01237   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 1
                                 DME Modulation Carvacrol inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [19]
                              Chlorhexidine acetate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02831   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 1
                                 DME Modulation Chlorhexidine acetate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [32]
                  Preclinical/Patented Drug Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Emodin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00692   XEOTIC Info Gene Form Protein
                                 Classification Drug in Preclinical Study
                                 DME Modulation Emodin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                  Drug Marketed but Withdrawn from Market Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Danthron Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO00516   XEOTIC Info Gene Form Protein
                                 Classification Drug Marketed but Withdrawn from Market
                                 DME Modulation Danthron inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                  Investigative Agent Click to Show/Hide the Full List of Xenobiotics:      10 Xenobiotics
                              Alliin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01931   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Alliin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Anthraflavic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02234   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Anthraflavic acid inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                              Carnitine hydrochloride Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02717   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Carnitine hydrochloride inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Furanone C-30 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03415   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Furanone C-30 inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [33]
                              Listerine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03912   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Listerine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [2]
                              Methyl gallate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04106   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Methyl gallate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [24]
                              Norspermidine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04331   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Norspermidine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [34]
                              Quinizarin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04775   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Quinizarin inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                              Rhein Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01455   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation Rhein inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [17]
                              S-carboxylmethyl-L-cysteine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04914   XEOTIC Info Gene Form Protein
                                 Classification Investigative Agent
                                 DME Modulation S-carboxylmethyl-L-cysteine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
      Other Chemical Compound(s) or Element(s)
                  Food Additive Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Propyl gallate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04727   XEOTIC Info Gene Form Protein
                                 Classification Food Additive
                                 DME Modulation Propyl gallate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [24]
                  Chemical Compound Click to Show/Hide the Full List of Xenobiotics:      14 Xenobiotics
                              Allylsulfenate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04723   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Allylsulfenate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Butyl gallate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02660   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Butyl gallate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [24]
                              Dibenzyl disulphide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03179   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Dibenzyl disulphide inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Dibenzyl sulphide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03180   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Dibenzyl sulphide inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Djenkolic acid Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03199   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Djenkolic acid inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Glycinamide hydrochloride Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03492   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Glycinamide hydrochloride inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              Hexyl gallate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03555   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Hexyl gallate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [24]
                              Octadecyl gallate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04350   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Octadecyl gallate inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [24]
                              S-(2-Aminoethyl)-L-cysteine hydrochloride Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04873   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation S-(2-Aminoethyl)-L-cysteine hydrochloride inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              S-(2-thienyl)-L-cysteine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04875   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation S-(2-thienyl)-L-cysteine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              S-(4-tolyl)-L-cysteine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04876   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation S-(4-tolyl)-L-cysteine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              S-ethyl-L-cysteine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04930   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation S-ethyl-L-cysteine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              S-phenyl-L-cysteine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04972   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation S-phenyl-L-cysteine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
                              S-propyl-L-cysteine Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04980   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation S-propyl-L-cysteine inhibits the drug-metabolizing activity of Unclear enzyme (DME-unclear) from Streptococcus mutans [1]
References
1 S-aryl-L-cysteine sulphoxides and related organosulphur compounds alter oral biofilm development and AI-2-based cell-cell communication. J Appl Microbiol. 2014 Nov;117(5):1472-86.
2 Systematic approach to optimizing specifically targeted antimicrobial peptides against Streptococcus mutans. Antimicrob Agents Chemother. 2010 May;54(5):2143-51.
3 Lumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization. Biochim Biophys Acta. 1998 Oct 22;1408(1):67-76.
4 A novel antimicrobial peptide from Bufo bufo gargarizans. Biochem Biophys Res Commun. 1996 Jan 5;218(1):408-13.
5 Solution structure of an antimicrobial peptide buforin II. FEBS Lett. 1996 Nov 25;398(1):87-90.
6 Targeted killing of Streptococcus mutans by a pheromone-guided "smart" antimicrobial peptide. Antimicrob Agents Chemother. 2006 Nov;50(11):3651-7.
7 Effect of a novel antimicrobial peptide chrysophsin-1 on oral pathogens and Streptococcus mutans biofilms. Peptides. 2012 Feb;33(2):212-9.
8 Clinical efficacy of a specifically targeted antimicrobial peptide mouth rinse: targeted elimination of Streptococcus mutans and prevention of demineralization. Caries Res. 2011;45(5):415-28.
9 Effect of MUC7 peptides on the growth of bacteria and on Streptococcus mutans biofilm. J Antimicrob Chemother. 2006 Jun;57(6):1100-9.
10 Isolation of a new L-amino acid oxidase from Crotalus durissus cascavella venom. Toxicon. 2006 Jan;47(1):47-57.
11 A novel antimicrobial peptide from the loach, Misgurnus anguillicaudatus. FEBS Lett. 1997 Jul 14;411(2-3):173-8.
12 Covalent structure of mutacin 1140 and a novel method for the rapid identification of lantibiotics. Eur J Biochem. 2000 Dec;267(23):6810-6.
13 Antimicrobial activity of neuropeptides against a range of micro-organisms from skin, oral, respiratory and gastrointestinal tract sites. J Neuroimmunol. 2008 Aug 30;200(1-2):11-6.
14 Antimicrobial and antibiofilm activity of pleurocidin against cariogenic microorganisms. Peptides. 2011 Aug;32(8):1748-54.
15 Inhibiting effects of Streptococcus salivarius on competence-stimulating peptide-dependent biofilm formation by Streptococcus mutans. Oral Microbiol Immunol. 2009 Apr;24(2):152-61.
16 The inhibitory effects of mushroom extracts on sucrose-dependent oral biofilm formation. Appl Microbiol Biotechnol. 2010 Mar;86(2):615-23.
17 In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones. Antimicrob Agents Chemother. 2007 Apr;51(4):1541-4.
18 Dental composite materials containing carolacton inhibit biofilm growth of Streptococcus mutans. Dent Mater. 2013 Nov;29(11):1188-99.
19 Thymol and carvacrol induce autolysis, stress, growth inhibition and reduce the biofilm formation by Streptococcus mutans. AMB Express. 2017 Dec;7(1):49.
20 High production of erythritol from Candida sorbosivorans SSE-24 and its inhibitory effect on biofilm formation of Streptococcus mutans. Bioresour Technol. 2015 Dec;198:31-8.
21 Inhibition of Gallic Acid on the Growth and Biofilm Formation of Escherichia coli and Streptococcus mutans. J Food Sci. 2015 Jun;80(6):M1299-305.
22 Kaurenoic Acid from Aralia continentalis Inhibits Biofilm Formation of Streptococcus mutans. Evid Based Complement Alternat Med. 2013;2013:160592.
23 Limonene inhibits streptococcal biofilm formation by targeting surface-associated virulence factors. J Med Microbiol. 2015 Aug;64(8):879-890.
24 Synthetic organic compounds with potential for bacterial biofilm inhibition, a path for the identification of compounds interfering with quorum sensing. Int J Antimicrob Agents. 2013 Dec;42(6):519-23.
25 The pseudomonas quinolone signal inhibits biofilm development of streptococcus mutans. Microbes Environ. 2015;30(2):189-91.
26 Activity of tyrosol against single and mixed-species oral biofilms. J Appl Microbiol. 2016 May;120(5):1240-9.
27 Anti-biofilm activity of Salvadora persica on cariogenic isolates of Streptococcus mutans: in vitro and molecular docking studies. Biofouling. 2012;28(1):29-38.
28 Antibiofilm potential of 16-oxo-cleroda-3, 13(14) E-diene-15 oic acid and its five new gama-amino gama-lactone derivatives against methicillin resistant Staphylococcus aureus and Streptococcus mutans. Eur J Med Chem. 2017 Sep 29;138:480-490.
29 Efflux inhibitor suppresses Streptococcus mutans virulence properties. FEMS Microbiol Lett. 2017 Apr 1;364(7).
30 Curcumin reduces Streptococcus mutans biofilm formation by inhibiting sortase A activity. Arch Oral Biol. 2013 Oct;58(10):1343-8.
31 Tea catechin epigallocatechin gallate inhibits Streptococcus mutans biofilm formation by suppressing gtf genes. Arch Oral Biol. 2012 Jun;57(6):678-83.
32 Inhibited biofilm formation and improved antibacterial activity of a novel nanoemulsion against cariogenic Streptococcus mutans in vitro and in vivo. Int J Nanomedicine. 2015 Jan 9;10:447-62.
33 Use of the quorum sensing inhibitor furanone C-30 to interfere with biofilm formation by Streptococcus mutans and its luxS mutant strain. Int J Antimicrob Agents. 2012 Jul;40(1):30-5.
34 Norspermidine changes the basic structure of S.utans biofilm. Mol Med Rep. 2017 Jan;15(1):210-220.

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