Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO04331)
Xenobiotics Name
Norspermidine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Investigative Agent
Structure
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3D MOL 2D MOL
PubChem CID
5942
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aminoglycoside N-acetyltransferase (aacC2) DME Info Acinetobacter baumannii [1]
Aminoglycoside O-phosphotransferase (aphA6) DME Info Acinetobacter baumannii [1]
Azoreductase (azoR) DME Info Escherichia coli [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [2]
Beta-lactamase (blaB) DME Info Klebsiella variicola [1]
Beta-lactamase (blaB) DME Info Escherichia coli [2]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [1]
Beta-lactamase (blaB) DME Info Acinetobacter baumannii [1]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [1]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [1]
Cytidine deaminase (cdd) DME Info Escherichia coli [1]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [2]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [1]
Unclear metabolic mechanism (DME-unclear) DME Info Streptococcus mutans [3]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [2]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [1]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [1]
Glutamate racemase (MurI) DME Info Escherichia coli [2]
Glutamate racemase (MurI) DME Info Streptococcus mutans [3]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [2]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [2]
Nicotinamidase (pncA) DME Info Acinetobacter baumannii [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
Glutamate racemase (MurI) DME Info Bacillus subtilis [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [2]
Glutamate racemase (MurI) DME Info Bacillus pumilus [2]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [2]
References
1 Activity of norspermidine on bacterial biofilms of multidrug-resistant clinical isolates associated with persistent extremity wound infections. Adv Exp Med Biol. 2017;973:53-70.
2 A small-molecule norspermidine and norspermidine-hosting polyelectrolyte coatings inhibit biofilm formation by multi-species wastewater culture. Appl Microbiol Biotechnol. 2015 Dec;99(24):10861-70.
3 Norspermidine changes the basic structure of S.utans biofilm. Mol Med Rep. 2017 Jan;15(1):210-220.

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