Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01496)
Xenobiotics Name
Ursolic acid
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
64945
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Mephenytoin 4-hydroxylase (CYP2C19) DME Info Homo sapiens [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [3]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
References
1 Differential gene expression for investigation of Escherichia coli biofilm inhibition by plant extract ursolic acid. Appl Environ Microbiol. 2005 Jul;71(7):4022-34.
2 Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo. Hepatology. 2006 Jan;43(1):134-43.
3 RNA-Seq-based transcriptome analysis of methicillin-resistant Staphylococcus aureus biofilm inhibition by ursolic acid and resveratrol. Sci Rep. 2014 Jun 27;4:5467.

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