General Information of Xenobiotics (ID: XEO02288)
Xenobiotics Name
Antimicrobial peptide ISAMP
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Bacillus pumilus [1], [2]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 3.2 ug/ml [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 3.2 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC = 3.2 ug/ml [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 3.2 ug/ml [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 3.2 ug/ml [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 3.2 ug/ml [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 3.2 ug/ml [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 3.2 ug/ml [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 3.2 ug/ml [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 3.2 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC = 3.2 ug/ml [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 3.2 ug/ml [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 10.4 ug/ml [1], [2]
NADPH-dependent nitroreductase (nfrA1) DME Info MIC = 12.3 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 3.2 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 3.2 ug/ml [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 3.2 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC = 12.3 ug/ml [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 3.2 ug/ml [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 3.2 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC = 12.3 ug/ml [1], [2]
General stress protein 14 (ywrO) DME Info MIC = 12.3 ug/ml [1], [2]
References
1 Exploring the sialome of the tick Ixodes scapularis. J Exp Biol. 2002 Sep;205(Pt 18):2843-64.
2 Purification and characterization of a novel salivary antimicrobial peptide from the tick, Ixodes scapularis. Biochem Biophys Res Commun. 2009 Dec 18;390(3):511-5.

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