Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03039)
Xenobiotics Name
Cyclopsychotride-A
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Klebsiella oxytoca [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella oxytoca [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella oxytoca [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 1.55 microM [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 1.55 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 1.55 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 5.80 microM [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 1.55 microM [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 1.55 microM [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 1.55 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 1.55 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 5.80 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 1.55 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 1.55 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 13.5 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 1.55 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 1.55 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 5.80 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 13.5 microM [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 1.55 microM [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 39.0 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 1.55 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 1.55 microM [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 1.55 microM [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 13.5 microM [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 1.55 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 1.55 microM [1], [2]
References
1 An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8.
2 Cyclopsychotride A, a biologically active, 31-residue cyclic peptide isolated from Psychotria longipes. J Nat Prod. 1994 Dec;57(12):1619-25.

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