General Information of Xenobiotics (ID: XEO05170)
Xenobiotics Name
Tricystine cyclic cystine TP
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
Azoreductase (azoR) DME Info Enterococcus faecalis [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Klebsiella oxytoca [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella oxytoca [1]
Unclear metabolic mechanism (DME-unclear) DME Info Enterococcus faecalis [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella oxytoca [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
Tyrosine decarboxylase (tdc) DME Info Enterococcus faecalis [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
VanA ligase (vanA) DME Info Enterococcus faecalis [1]
VanB ligase (vanB) DME Info Enterococcus faecalis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 3.0 microM [1]
Azoreductase (azoR) DME Info MIC = 1.0 microM [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 3.0 microM [1]
Beta-lactamase (blaB) DME Info MIC = 3.0 microM [1]
Beta-lactamase (blaB) DME Info MIC = 2.1 microM [1]
Chloramphenicolase (chlR) DME Info MIC = 3.0 microM [1]
Glycoside hydrolase (cscA) DME Info MIC = 3.0 microM [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 3.0 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 3.0 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 2.1 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 1.0 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 3.0 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 3.0 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 5.0 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 3.0 microM [1]
Glutamate racemase (MurI) DME Info MIC = 3.0 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 2.1 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 5.0 microM [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 3.0 microM [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 1.0 microM [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 3.0 microM [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 3.0 microM [1]
NADH dehydrogenase (nuoE) DME Info MIC = 3.0 microM [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 5.0 microM [1]
Tyrosine decarboxylase (tdc) DME Info MIC = 1.0 microM [1]
Tyramine oxidase (tynA) DME Info MIC = 3.0 microM [1]
Beta-glucuronidase (uidA) DME Info MIC = 3.0 microM [1]
VanA ligase (vanA) DME Info MIC = 1.0 microM [1]
VanB ligase (vanB) DME Info MIC = 1.0 microM [1]
References
1 Marked increase in membranolytic selectivity of novel cyclic tachyplesins constrained with an antiparallel two-beta strand cystine knot framework. Biochem Biophys Res Commun. 2000 Jan 27;267(3):783-90.

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