General Information of Xenobiotics (ID: XEO02774)
Xenobiotics Name
Cecropin-P1
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
Azoreductase (azoR) DME Info Streptococcus pyogenes [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Salmonella enterica [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Salmonella enterica [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Salmonella enterica [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Salmonella enterica [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 0.3 microM [1], [2]
Azoreductase (azoR) DME Info MIC = 19 microM [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 0.3 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 0.3 microM [1], [2]
Beta-lactamase (blaB) DME Info MIC = 0.9 microM [1], [2]
Chloramphenicolase (chlR) DME Info MIC = 0.3 microM [1], [2]
Glycoside hydrolase (cscA) DME Info MIC = 0.3 microM [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 0.3 microM [1], [2]
Cytochrome P450 102A1 (cyp102) DME Info MIC = 1.8 microM [1], [2]
Cytochrome P450 MEG (cyp106) DME Info MIC = 1.8 microM [1], [2]
Cytochrome P450 21A2 (cyp21) DME Info MIC = 1.8 microM [1], [2]
Cytochrome P450 BM3 (cypBM3) DME Info MIC = 1.8 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.3 microM [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.9 microM [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 0.3 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.3 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 5.9 microM [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.3 microM [1], [2]
Glutamate racemase (MurI) DME Info MIC = 0.3 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 5.9 microM [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC = 0.3 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.3 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.9 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.3 microM [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.9 microM [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC = 0.3 microM [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 5.9 microM [1], [2]
Tyramine oxidase (tynA) DME Info MIC = 0.3 microM [1], [2]
Beta-glucuronidase (uidA) DME Info MIC = 0.3 microM [1], [2]
References
1 Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum. Biochem J. 2005 Aug 15;390(Pt 1):207-14.
2 The structure of the mammalian antibacterial peptide cecropin P1 in solution, determined by proton-NMR. Eur J Biochem. 1992 Oct 1;209(1):163-9.

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