Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO04057)
Xenobiotics Name
Melittin
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
Azoreductase (azoR) DME Info Streptococcus pyogenes [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [1]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [1]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [1]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [2]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [3]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
Glutamate racemase (MurI) DME Info Bacillus pumilus [3]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 0.8 microM [1]
Azoreductase (azoR) DME Info MIC = 0.5 microM [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 0.8 microM [1]
Beta-lactamase (blaB) DME Info MIC = 0.8 microM [1]
Chloramphenicolase (chlR) DME Info MIC = 0.8 microM [1]
Glycoside hydrolase (cscA) DME Info MIC = 0.8 microM [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 0.8 microM [1]
Cytochrome P450 102A1 (cyp102) DME Info MIC = 0.6 microM [1]
Cytochrome P450 MEG (cyp106) DME Info MIC = 0.6 microM [1]
Cytochrome P450 21A2 (cyp21) DME Info MIC = 0.6 microM [1]
Cytochrome P450 BM3 (cypBM3) DME Info MIC = 0.6 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.8 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 0.8 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 0.8 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 3 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.8 microM [1]
Glutamate racemase (MurI) DME Info MIC = 0.8 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 3 microM [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 0.8 microM [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 0.2 microM [2]
NADPH-dependent nitroreductase (nfrA1) DME Info MIC = 0.2 microM [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 0.8 microM [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 0.8 microM [1]
NADH dehydrogenase (nuoE) DME Info MIC = 0.8 microM [3]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 3 microM [1]
Glutamate racemase (MurI) DME Info MIC = 0.2 microM [1]
Tyramine oxidase (tynA) DME Info MIC = 0.8 microM [1]
Beta-glucuronidase (uidA) DME Info MIC = 0.8 microM [1]
Glutamate racemase (MurI) DME Info MIC = 0.2 microM [3]
General stress protein 14 (ywrO) DME Info MIC = 0.2 microM [1]
References
1 Identification of a novel melittin isoform from Africanized Apis mellifera venom. Peptides. 2010 Aug;31(8):1473-9.
2 Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of melittin and phospholipase A(2) levels. Toxicon. 2010 Sep 1;56(3):355-62.
3 Nucleotide sequence of cloned cDNA coding for honeybee prepromelittin. Eur J Biochem. 1983 Sep 1;135(1):123-6.

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