Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO04904)
Xenobiotics Name
Sapecin defensin
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Escherichia coli [1], [2]
Beta-lactamase (blaB) DME Info Shigella sonnei [1], [2]
Chloramphenicolase (chlR) DME Info Escherichia coli [1], [2]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1], [2]
Cytochrome P450 125A3 (cyp125) DME Info Mycolicibacterium smegmatis [1], [2]
Cytochrome P450 142A2 (cyp142) DME Info Mycolicibacterium smegmatis [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1], [2]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Escherichia coli [1], [2]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1], [2]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1], [2]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1], [2]
Tyramine oxidase (tynA) DME Info Escherichia coli [1], [2]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1], [2]
Glutamate racemase (MurI) DME Info Bacillus pumilus [1], [2]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC > 78 ug/ml [1], [2]
L,D-carboxypeptidase A (ldcA) DME Info MIC > 78 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC > 78 ug/ml [1], [2]
Beta-lactamase (blaB) DME Info MIC > 78 ug/ml [1], [2]
Chloramphenicolase (chlR) DME Info MIC > 78 ug/ml [1], [2]
Glycoside hydrolase (cscA) DME Info MIC > 78 ug/ml [1], [2]
NADPH-dependent curcumin reductase (curA) DME Info MIC > 78 ug/ml [1], [2]
Cytochrome P450 125A3 (cyp125) DME Info MIC = 78 ug/ml [1], [2]
Cytochrome P450 142A2 (cyp142) DME Info MIC = 78 ug/ml [1], [2]
Unclear metabolic mechanism (DME-unclear) DME Info MIC > 78 ug/ml [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC > 78 ug/ml [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC > 78 ug/ml [1], [2]
Molybdopterin-dependent enzyme (molD) DME Info MIC > 78 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC > 78 ug/ml [1], [2]
N-ethylmaleimide reductase (nemA) DME Info MIC > 78 ug/ml [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 5.0 ug/ml [1], [2]
NADPH-dependent nitroreductase (nfrA1) DME Info MIC = 20.0 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC > 78 ug/ml [1], [2]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC > 78 ug/ml [1], [2]
NADH dehydrogenase (nuoE) DME Info MIC > 78 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC = 20.0 ug/ml [1], [2]
Tyramine oxidase (tynA) DME Info MIC > 78 ug/ml [1], [2]
Beta-glucuronidase (uidA) DME Info MIC > 78 ug/ml [1], [2]
Glutamate racemase (MurI) DME Info MIC = 20.0 ug/ml [1], [2]
General stress protein 14 (ywrO) DME Info MIC = 20.0 ug/ml [1], [2]
References
1 Purification of three antibacterial proteins from the culture medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina. J Biol Chem. 1988 Nov 15;263(32):17112-6.
2 Determination of the disulfide array in sapecin, an antibacterial peptide of Sarcophaga peregrina (flesh fly). J Biochem. 1990 Apr;107(4):514-8.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.