General Information of Drug-Metabolizing Enzyme (DME ID: DME1617)
DME Name Oxygen-insensitive NADPH nitroreductase B (nfsB), Salmonella enterica DME Info
UniProt ID
NFSB_SALTY
EC Number    EC: 1.5.1.34     (Click to Show/Hide the Complete EC Tree)
Oxidoreductase
CH-NH donor oxidoreductase
NAD/NADP acceptor oxidoreductase
EC: 1.5.1.34
Lineage    Species: Salmonella enterica     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Enterobacteriaceae
Genus: Salmonella
Species: Salmonella enterica
Subspecies: Salmonella enterica subsp. enterica serovar Typhimurium TA100
Interactome
Interactions between Xenobiotics and DME (XEOTIC)
      Amino Acid(s), Peptide(s) or Protein(s)
                  Peptide Click to Show/Hide the Full List of Xenobiotics:    216 Xenobiotics
                              Androctonin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02224   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Androctonin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [1]
                              Anopheles cecropin-A amidated isoform Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02230   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Anopheles cecropin-A amidated isoform inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.1-0.25 microM) [2], [3]
                              Antibacterial peptide PMAP-23 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02242   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antibacterial peptide PMAP-23 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 microM) [4]
                              Antibacterial peptide PMAP-36 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02243   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antibacterial peptide PMAP-36 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 48 microM) [5]
                              Antibacterial peptide PMAP-37 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02244   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antibacterial peptide PMAP-37 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 microM) [6]
                              Antibacterial protein PR-39 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02248   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antibacterial protein PR-39 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 microM) [7], [8]
                              Antimicrobial peptide HP(2-20) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02283   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide HP(2-20) inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1.56 ug/ml) [9]
                              Antimicrobial peptide HsAp1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02284   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide HsAp1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 25.0 microM) [10]
                              Antimicrobial peptide HsAp2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02285   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide HsAp2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 25.0 microM) [10]
                              Antimicrobial peptide HsAp3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02286   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide HsAp3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 25.0 microM) [10]
                              Antimicrobial peptide HsAp4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02287   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Antimicrobial peptide HsAp4 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 25.0 microM) [10]
                              Apidaecin-1A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02304   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Apidaecin-1A inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.1 ug/ml) [11]
                              Apidaecin-1B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02305   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Apidaecin-1B inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.1 ug/ml) [11], [12]
                              Apidaecin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02306   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Apidaecin-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.1 ug/ml) [11]
                              Arenicin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02317   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Arenicin-1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 300 microM) [13], [14]
                              Bac2A variant Bac8a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02357   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant Bac8a inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 31 ug/ml) [15]
                              Bac2A variant Bac8b Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02358   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant Bac8b inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 ug/ml) [15]
                              Bac2A variant Bac8c Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02360   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant Bac8c inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [15]
                              Bac2A variant Bac8d Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02361   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant Bac8d inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 31 ug/ml) [15]
                              Bac2A variant G1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03428   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant G1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 63 ug/ml) [15]
                              Bac2A variant G12 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03430   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant G12 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 63 ug/ml) [15]
                              Bac2A variant G2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03434   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant G2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 31 ug/ml) [15]
                              Bac2A variant K7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03684   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant K7 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 63 ug/ml) [15]
                              Bac2A variant R11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04783   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant R11 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [15]
                              Bac2A variant R2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04784   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant R2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [15]
                              Bac2A variant R3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04785   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant R3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [15]
                              Bac2A variant R5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04786   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant R5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 31 ug/ml) [15]
                              Bac2A variant Sub2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05000   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant Sub2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [15]
                              Bac2A variant Sub3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05001   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant Sub3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [15]
                              Bac2A variant Sub5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05002   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant Sub5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [15]
                              Bac2A variant Sub6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05003   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant Sub6 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 ug/ml) [15]
                              Bac2A variant W10 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05264   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant W10 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [15]
                              Bac2A variant W3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05267   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bac2A variant W3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [15]
                              Bactenecin 5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02370   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin 5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2-10 microM) [16]
                              Bactenecin 7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02371   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin 7 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 12 ug/ml) [17]
                              Bactenecin bac2I-NH2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02356   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin bac2I-NH2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [18]
                              Bactenecin bacP2R-NH2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02366   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin bacP2R-NH2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 32 ug/ml) [18]
                              Bactenecin bacP3R-V Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02368   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin bacP3R-V inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [18]
                              Bactenecin cyclic derivative BacP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02365   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin cyclic derivative BacP1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC > 64 ug/ml) [18]
                              Bactenecin cyclic derivative BacP3R Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02367   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin cyclic derivative BacP3R inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [18]
                              Bactenecin cyclic derivative BacR Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02369   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin cyclic derivative BacR inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [18]
                              Bactenecin cyclic derivative BacW Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02388   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin cyclic derivative BacW inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [18]
                              Bactenecin cyclic derivative BacW2R Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02389   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin cyclic derivative BacW2R inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [18]
                              Bactenecin-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02735   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bactenecin-5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 ug/ml) [19]
                              Bacteriocin L-1077 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02378   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bacteriocin L-1077 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.19 ug/ml) [20]
                              Big defensin crabs Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02451   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Big defensin crabs inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [21], [22]
                              Bovine cathelicidin BMAP-34 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02466   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bovine cathelicidin BMAP-34 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3 microM) [23], [24]
                              Bradykinin-potentiating BmK3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02491   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Bradykinin-potentiating BmK3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2.3 microM) [25], [26]
                              Buforin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02649   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Buforin-1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [27], [28]
                              Buforin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02650   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Buforin-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 ug/ml) [27], [28]
                              Cathelicidin-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02739   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cathelicidin-5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 microM) [29], [30]
                              Cathelicidin-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02740   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cathelicidin-6 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 ug/ml) [29], [31]
                              Cecropin-P1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02774   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cecropin-P1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.9 microM) [32], [33]
                              CEMA protein MBI-28 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02799   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CEMA protein MBI-28 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3 ug/ml) [34]
                              CEME protein MBI-27 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02800   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CEME protein MBI-27 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [34]
                              CM1 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02885   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CM1 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 5 ug/ml) [34]
                              CM2 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02886   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CM2 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [34]
                              CM3 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02887   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CM3 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3 ug/ml) [34]
                              CM4 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02888   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CM4 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3 ug/ml) [34]
                              CM5 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02889   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CM5 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 29 ug/ml) [34]
                              CM6 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02890   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CM6 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [34]
                              CM7 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02891   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CM7 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3 ug/ml) [34]
                              CP alpha 1 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02947   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP alpha 1 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 43 ug/ml) [34]
                              CP alpha 2 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02948   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP alpha 2 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [34]
                              CP alpha 3 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02949   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP alpha 3 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [34]
                              CP201 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02933   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP201 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 43 ug/ml) [34]
                              CP202 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02934   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP202 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 ug/ml) [34]
                              CP203 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02935   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP203 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [34]
                              CP207 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02937   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP207 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3 ug/ml) [34]
                              CP26 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02940   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP26 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3 ug/ml) [34]
                              CP29 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02941   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation CP29 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [34]
                              Cryptdin related peptide CRS4C-1a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02958   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cryptdin related peptide CRS4C-1a inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [35]
                              Cryptdin related peptide CRS4C-1d Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02959   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cryptdin related peptide CRS4C-1d inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [35]
                              Cryptdin related peptide CRS4C-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02960   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cryptdin related peptide CRS4C-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [35]
                              Cryptdin related peptide CRS4C-2b Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02961   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cryptdin related peptide CRS4C-2b inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [35]
                              Cryptdin related sequence CRS4C-3c Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02955   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cryptdin related sequence CRS4C-3c inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [35]
                              Cyclic cationic V1 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03029   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cyclic cationic V1 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.005 microM) [36]
                              Cyclic cationic V2 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03030   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cyclic cationic V2 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.005 microM) [36]
                              Cyclic cationic V3 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03031   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cyclic cationic V3 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.3 microM) [36]
                              Cyclic cationic V4 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03032   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cyclic cationic V4 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.005 microM) [36]
                              Cyclic cationic V5 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03033   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cyclic cationic V5 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.005 microM) [36]
                              Cyclic cationic V6 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03034   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cyclic cationic V6 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.528 microM) [36]
                              Cyclic cationic V7 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03035   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cyclic cationic V7 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.004 microM) [36]
                              Cytotoxic linear peptide IsCT Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03043   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Cytotoxic linear peptide IsCT inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 microM) [37], [38]
                              D-amino acid substitution of K9L8W Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03060   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation D-amino acid substitution of K9L8W inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 microM) [39]
                              Defensin-like turtle protein TEWP Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03125   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Defensin-like turtle protein TEWP inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [40]
                              Dermaseptin-like PBN2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03162   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dermaseptin-like PBN2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3.1 microM) [41]
                              Dermatoxin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03164   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Dermatoxin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [42]
                              Drosophila cecropin-A1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03224   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Drosophila cecropin-A1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.5-1 microM) [43], [44]
                              Enterocin 96 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03250   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Enterocin 96 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [45]
                              Enterocin AS-48 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03251   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Enterocin AS-48 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [46]
                              Fish NRC-1 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04335   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Fish NRC-1 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 ug/ml) [47]
                              Fish NRC-10 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04336   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Fish NRC-10 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 ug/ml) [47]
                              Fish NRC-16 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04338   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Fish NRC-16 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.5 ug/ml) [47]
                              Fish NRC-2 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04339   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Fish NRC-2 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 64 ug/ml) [47]
                              Fish NRC-3 peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04340   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Fish NRC-3 peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [47]
                              Fowlicidin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02734   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Fowlicidin-1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.40 microM) [48]
                              Fowlicidin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02736   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Fowlicidin-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.66 microM) [49]
                              Fowlicidin-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02738   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Fowlicidin-3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 microM) [50]
                              Gaegurin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03437   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 150 ug/ml) [51]
                              Gaegurin-3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03438   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 150 ug/ml) [51]
                              Gaegurin-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03439   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-4 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 200 ug/ml) [52]
                              Gaegurin-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03440   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 200 ug/ml) [51]
                              Gaegurin-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03441   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gaegurin-6 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 200 ug/ml) [51]
                              Gallinacin-13 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03462   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gallinacin-13 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [53]
                              Gallinacin-4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03464   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gallinacin-4 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [53]
                              Gallinacin-5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03465   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gallinacin-5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [53]
                              Gallinacin-6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03466   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gallinacin-6 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [53]
                              Gallinacin-8 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03467   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Gallinacin-8 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [53]
                              GAPDH-related antimicrobial YFGAP Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05308   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation GAPDH-related antimicrobial YFGAP inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.9 ug/ml) [54]
                              GGN4 analogue peptide D16W Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03052   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation GGN4 analogue peptide D16W inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 50 ug/ml) [55]
                              Grammistin Gs A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03504   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Grammistin Gs A inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC > 50 ug/ml) [56]
                              Grammistin Gs B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03505   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Grammistin Gs B inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 12.5 ug/ml) [56]
                              Grammistin Gs C Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03506   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Grammistin Gs C inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 12.5 ug/ml) [56]
                              Hadrurin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03519   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Hadrurin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [57]
                              HP(2-20) analogue Anal 1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02207   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.39 ug/ml) [9]
                              HP(2-20) analogue Anal 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02208   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.78 ug/ml) [9]
                              HP(2-20) analogue Anal 3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02209   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.39 ug/ml) [9]
                              HP(2-20) analogue Anal 4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02210   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 4 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 12.5 ug/ml) [9]
                              HP(2-20) analogue Anal 5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02211   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 12.5 ug/ml) [9]
                              HP(2-20) analogue Anal 6 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02212   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 6 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.39 ug/ml) [9]
                              HP(2-20) analogue Anal 7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02213   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation HP(2-20) analogue Anal 7 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.39 ug/ml) [9]
                              Hydramacin Hm-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03609   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Hydramacin Hm-1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [58], [59]
                              Indolicidin derivative chain a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02820   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Indolicidin derivative chain a inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 64 ug/ml) [60]
                              Insect attacin-C Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02333   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect attacin-C inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC > 200 microM) [61]
                              Insect cecropin-A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02768   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Insect cecropin-A inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1-2.5 ug/ml) [62]
                              IsCT analog E7K [K7] Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01820   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation IsCT analog E7K [K7] inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 microM) [37]
                              IsCT analog K7,P8,K11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01819   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation IsCT analog K7,P8,K11 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 microM) [37]
                              IsCT analog L6,K11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01821   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation IsCT analog L6,K11 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 microM) [37]
                              IsCT analog W6A [A6] Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01811   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation IsCT analog W6A [A6] inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC > 64 microM) [37]
                              IsCT analog W6L [L6] Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01822   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation IsCT analog W6L [L6] inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 microM) [37]
                              Kunitz-type serine protease inhibitor Xb-KTI Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03721   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Kunitz-type serine protease inhibitor Xb-KTI inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 10 microM) [63]
                              L-amino-acid oxidase Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03793   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L-amino-acid oxidase inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 microM) [64]
                              L5K5Wn model peptide L5K5W1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03746   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [65]
                              L5K5Wn model peptide L5K5W10 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03747   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W10 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 ug/ml) [65]
                              L5K5Wn model peptide L5K5W11 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03748   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W11 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [65]
                              L5K5Wn model peptide L5K5W2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03749   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [65]
                              L5K5Wn model peptide L5K5W3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03750   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [65]
                              L5K5Wn model peptide L5K5W4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03751   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W4 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [65]
                              L5K5Wn model peptide L5K5W5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03752   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [65]
                              L5K5Wn model peptide L5K5W7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03754   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W7 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [65]
                              L5K5Wn model peptide L5K5W8 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03755   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W8 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [65]
                              L5K5Wn model peptide L5K5W9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03756   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation L5K5Wn model peptide L5K5W9 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [65]
                              Linear bactenecin bac2S-NH2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03904   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Linear bactenecin bac2S-NH2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 32 ug/ml) [18]
                              Linear bactenecin bacS-NH2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03905   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Linear bactenecin bacS-NH2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC > 64 ug/ml) [18]
                              LL-37(17-29) peptide Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03928   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation LL-37(17-29) peptide inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 microM) [66], [67]
                              M-theraphotoxin-Gr1a Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04142   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation M-theraphotoxin-Gr1a inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 32.64 microM) [68]
                              Mammal mBMAP28 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04039   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Mammal mBMAP28 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 microM) [29]
                              Microcin 7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04111   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Microcin 7 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [69]
                              Microcin E492 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04112   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Microcin E492 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1.2 microM) [70]
                              Microcin L Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04114   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Microcin L inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [71], [72]
                              Misgurin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04117   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Misgurin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [73]
                              Myeloid antimicrobial peptide BMAP-27 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04158   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Myeloid antimicrobial peptide BMAP-27 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 microM) [29]
                              Myeloid antimicrobial peptide BMAP-28 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04159   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Myeloid antimicrobial peptide BMAP-28 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 microM) [29]
                              Myxinidin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04172   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Myxinidin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [74]
                              Neutrophil antibiotic peptide NP-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04252   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Neutrophil antibiotic peptide NP-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [75], [76]
                              Pep-1 peptide derivative Pep-1-K Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04526   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pep-1 peptide derivative Pep-1-K inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1.0 microM) [77]
                              Pilosulin P1(1-20) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04426   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pilosulin P1(1-20) inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 microM) [78]
                              Piscidin Pis-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04613   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Piscidin Pis-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 10-20 microM) [79]
                              Plant defensin VaD1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05222   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plant defensin VaD1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [80]
                              Plant JCpep7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03671   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plant JCpep7 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 48 ug/ml) [81]
                              Plasticin PD36 KF Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04627   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Plasticin PD36 KF inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 25.25 microM) [82]
                              Pleurocidin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04640   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8.8-17.7 microM) [83]
                              Pleurocidin-like peptide AP1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04642   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide AP1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [47]
                              Pleurocidin-like peptide AP2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04643   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide AP2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [47]
                              Pleurocidin-like peptide AP3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04644   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide AP3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [47]
                              Pleurocidin-like peptide GC3.2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04645   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide GC3.2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 32 ug/ml) [47]
                              Pleurocidin-like peptide GC3.8 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04646   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide GC3.8 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1 ug/ml) [47]
                              Pleurocidin-like peptide GcSc4B7 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04647   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide GcSc4B7 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [47]
                              Pleurocidin-like peptide GcSc4C5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04648   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide GcSc4C5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 ug/ml) [47]
                              Pleurocidin-like peptide Hb18 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04649   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide Hb18 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC > 64 ug/ml) [47]
                              Pleurocidin-like peptide Hb26 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04650   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide Hb26 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 16 ug/ml) [47]
                              Pleurocidin-like peptide WF3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04651   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide WF3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 64 ug/ml) [47], [84]
                              Pleurocidin-like peptide WF4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04652   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide WF4 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4 ug/ml) [47], [84]
                              Pleurocidin-like peptide WFX Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04653   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide WFX inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC > 64 ug/ml) [85]
                              Pleurocidin-like peptide WFY Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04654   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide WFY inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 64 ug/ml) [85]
                              Pleurocidin-like peptide YT2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04655   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pleurocidin-like peptide YT2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [47]
                              PM1 linear derivative PM1-S Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04660   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation PM1 linear derivative PM1-S inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2 ug/ml) [86]
                              Polyphemusin-1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04690   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Polyphemusin-1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.25 ug/ml) [87], [86]
                              Ponericin G1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04695   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin G1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [88]
                              Ponericin G3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04696   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin G3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [88]
                              Ponericin-L2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04699   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-L2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [88]
                              Ponericin-W1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04700   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [88]
                              Ponericin-W3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04701   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [88]
                              Ponericin-W4 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04702   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W4 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [88]
                              Ponericin-W5 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04703   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Ponericin-W5 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [88]
                              Porcine beta-defensin pBD-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04481   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Porcine beta-defensin pBD-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [89]
                              Pyrrhocoricin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04770   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Pyrrhocoricin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 5 microM) [90]
                              Recombinant Crassostrea Gigas Defensin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04840   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Recombinant Crassostrea Gigas Defensin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC > 20 microM) [91]
                              Rhesus theta-defensin 1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04848   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Rhesus theta-defensin 1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [92]
                              Rhesus theta-defensin 2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04849   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Rhesus theta-defensin 2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [92]
                              Rhesus theta-defensin 3 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04850   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Rhesus theta-defensin 3 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [92]
                              Shepherin I Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04931   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Shepherin I inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [93]
                              shepherin II Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04932   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation shepherin II inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [93]
                              Single AA substitution D16W-N23 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03053   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Single AA substitution D16W-N23 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 125 ug/ml) [55]
                              SMAP-29 derivative A19 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01810   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SMAP-29 derivative A19 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1.0 microM) [94]
                              SMAP-29 derivative K2,7,13 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01817   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SMAP-29 derivative K2,7,13 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 4.0 microM) [94]
                              SMAP-29 derivative K22,25,27 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01818   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SMAP-29 derivative K22,25,27 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1.0 microM) [94]
                              SMAP-29 peptide derivative(1-17) Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04956   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation SMAP-29 peptide derivative(1-17) inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8.0 microM) [94]
                              Spheniscin-2 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04971   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Spheniscin-2 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 6-12 microM) [95], [96]
                              Spider gomesin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03498   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Spider gomesin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.8-1.6 microM) [97]
                              Spinigerin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04974   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Spinigerin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 3-6 microM) [98], [99]
                              Stomoxyn Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04995   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Stomoxyn inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.39-0.78 microM) [99], [100]
                              Styelin A Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04998   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Styelin A inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 5 ug/ml) [101]
                              Styelin B Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04999   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Styelin B inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 5 ug/ml) [101]
                              Tachycitin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05020   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tachycitin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [102], [103]
                              Thanatin Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05120   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Thanatin inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 0.6-1.2 microM) [104], [105]
                              Tridecaptin A1 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05171   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tridecaptin A1 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [106]
                              Tritrpticin derivative TPA Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05161   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tritrpticin derivative TPA inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 32 ug/ml) [107]
                              Tritrpticin derivative TPG Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05162   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tritrpticin derivative TPG inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 32 ug/ml) [107]
                              Tritrpticin peptide derivative TWF Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05193   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Tritrpticin peptide derivative TWF inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 8 ug/ml) [107]
                              Turtle egg-white protein TEWP Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05119   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Turtle egg-white protein TEWP inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [40]
                              V681 peptide derivative S11AD Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04886   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation V681 peptide derivative S11AD inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 1.0 ug/ml) [108]
                              V681 peptide derivative S11G Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO04880   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation V681 peptide derivative S11G inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 12.7 ug/ml) [108]
                              V681 peptide derivative V13G Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05212   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation V681 peptide derivative V13G inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 2.5 ug/ml) [108]
                              Venom antimicrobial peptide-9 Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO05231   XEOTIC Info Gene Form Protein
                                 Classification Peptide
                                 DME Modulation Venom antimicrobial peptide-9 inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica (MIC = 10.9 microM) [109]
      Natural Product(s), Extract(s) or Medicine(s)
                  Bacterial Extract Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Bacillus licheniformis SP1 culture supernatant Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02990   XEOTIC Info Gene Form Protein
                                 Classification Bacterial Extract
                                 DME Modulation Bacillus licheniformis SP1 culture supernatant inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [110]
                  Natural Product Click to Show/Hide the Full List of Xenobiotics:        1 Xenobiotics
                              Anthranilate Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02235   XEOTIC Info Gene Form Protein
                                 Classification Natural Product
                                 DME Modulation Anthranilate inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [111]
      Pharmaceutical Agent(s)
                  Drug in Phase 1 Clinical Trial Click to Show/Hide the Full List of Xenobiotics:        2 Xenobiotics
                              Carvacrol Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01237   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 1
                                 DME Modulation Carvacrol inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [112]
                              L-tryptophan Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO03968   XEOTIC Info Gene Form Protein
                                 Classification Highest Clinical Status: Phase 1
                                 DME Modulation L-tryptophan inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [111]
      Other Chemical Compound(s) or Element(s)
                  Chemical Compound Click to Show/Hide the Full List of Xenobiotics:        4 Xenobiotics
                              (Z)-4-bromo-5-(bromomethylene)-3-ethyl-2(5H)-furanone Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01802   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation (Z)-4-bromo-5-(bromomethylene)-3-ethyl-2(5H)-furanone inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [113]
                              2-Hexylmaleic anhydride Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01944   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation 2-Hexylmaleic anhydride inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [113]
                              3-hexyl-4-bromo-5-methylene-2(5H)-furanone Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO01990   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation 3-hexyl-4-bromo-5-methylene-2(5H)-furanone inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [113]
                              Bromohexylmaleic anhydride Click to Show/Hide the Detail Inhibition
                                 XEOTIC ID XEO02641   XEOTIC Info Gene Form Protein
                                 Classification Chemical Compound
                                 DME Modulation Bromohexylmaleic anhydride inhibits the drug-metabolizing activity of Oxygen-insensitive NADPH nitroreductase B (nfsB) from Salmonella enterica [113]
References
1 Androctonin, a novel antimicrobial peptide from scorpion Androctonus australis: solution structure and molecular dynamics simulations in the presence of a lipid monolayer. J Biomol Struct Dyn. 1999 Oct;17(2):367-80.
2 Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae. Insect Mol Biol. 2000 Feb;9(1):75-84.
3 Genomic organization and regulation of three cecropin genes in Anopheles gambiae. Insect Mol Biol. 2002 Dec;11(6):517-25.
4 Molecular cloning and chemical synthesis of a novel antibacterial peptide derived from pig myeloid cells. J Biol Chem. 1994 Mar 18;269(11):7855-8.
5 Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA. FEBS Lett. 1994 Jan 17;337(3):303-7.
6 PMAP-37, a novel antibacterial peptide from pig myeloid cellscDNA cloning, chemical synthesis and activity. Eur J Biochem. 1995 Mar 15;228(3):941-6.
7 Amino acid sequence of PR-39Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides. Eur J Biochem. 1991 Dec 18;202(3):849-54.
8 Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7085-9.
9 Interactions between the plasma membrane and the antimicrobial peptide HP (2-20) and its analogues derived from Helicobacter pylori. Biochem J. 2006 Feb 15;394(Pt 1):105-14.
10 A novel class of antimicrobial peptides from the scorpion Heterometrus spinifer. Peptides. 2012 Dec;38(2):389-94.
11 Apidaecins: antibacterial peptides from honeybees. EMBO J. 1989 Aug;8(8):2387-91.
12 Isolation and characterization of abaecin, a major antibacterial response peptide in the honeybee (Apis mellifera). Eur J Biochem. 1990 Jan 26;187(2):381-6.
13 Purification and primary structure of two isoforms of arenicin, a novel antimicrobial peptide from marine polychaeta Arenicola marina. FEBS Lett. 2004 Nov 5;577(1-2):209-14.
14 Structure and mode of action of the antimicrobial peptide arenicin. Biochem J. 2008 Feb 15;410(1):113-22.
15 High-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-12.
16 Amino acid sequences of two proline-rich bactenecinsAntimicrobial peptides of bovine neutrophils. J Biol Chem. 1990 Nov 5;265(31):18871-4.
17 Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils. Infect Immun. 1989 Oct;57(10):3142-6.
18 Improved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-6.
19 Purification and properties of proline-rich antimicrobial peptides from sheep and goat leukocytes. Infect Immun. 1999 Aug;67(8):4106-11.
20 Isolation of Lactobacillus salivarius 1077 (NRRL B-50053) and characterization of its bacteriocin, including the antimicrobial activity spectrum. Appl Environ Microbiol. 2011 Apr;77(8):2749-54.
21 A novel big defensin identified in horseshoe crab hemocytes: isolation, amino acid sequence, and antibacterial activity. J Biochem. 1995 May;117(5):1131-7.
22 A novel beta-defensin structure: a potential strategy of big defensin for overcoming resistance by Gram-positive bacteria. Biochemistry. 2008 Oct 7;47(40):10611-9.
23 Structural organization of the bovine cathelicidin gene family and identification of a novel member. FEBS Lett. 1997 Nov 17;417(3):311-5.
24 Biological characterization of a novel mammalian antimicrobial peptide. Biochim Biophys Acta. 1998 Oct 23;1425(2):361-8.
25 Cloning and characterization of a novel cDNA sequence encoding the precursor of a novel venom peptide (BmKbpp) related to a bradykinin-potentiating peptide from Chinese scorpion Buthus martensii Karsch. IUBMB Life. 2000 Mar;49(3):207-10.
26 Characterization of BmKbpp, a multifunctional peptide from the Chinese scorpion Mesobuthus martensii Karsch: gaining insight into a new mechanism for the functional diversification of scorpion venom peptides. Peptides. 2012 Jan;33(1):44-51.
27 A novel antimicrobial peptide from Bufo bufo gargarizans. Biochem Biophys Res Commun. 1996 Jan 5;218(1):408-13.
28 Solution structure of an antimicrobial peptide buforin II. FEBS Lett. 1996 Nov 25;398(1):87-90.
29 Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities. J Biol Chem. 1996 Nov 8;271(45):28375-81.
30 Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides. Eur J Biochem. 1996 Jun 15;238(3):769-76.
31 Sequence analysis and polymorphism discovery in 4 members of the bovine cathelicidin gene family. J Hered. 2009 Mar-Apr;100(2):241-5.
32 Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum. Biochem J. 2005 Aug 15;390(Pt 1):207-14.
33 The structure of the mammalian antibacterial peptide cecropin P1 in solution, determined by proton-NMR. Eur J Biochem. 1992 Oct 1;209(1):163-9.
34 Biological properties of structurally related alpha-helical cationic antimicrobial peptides. Infect Immun. 1999 Apr;67(4):2005-9.
35 Increased diversity of intestinal antimicrobial peptides by covalent dimer formation. Nat Immunol. 2004 Aug;5(8):836-43.
36 De novo design of potent antimicrobial peptides. Antimicrob Agents Chemother. 2004 Sep;48(9):3349-57.
37 Antibiotic activity and structural analysis of the scorpion-derived antimicrobial peptide IsCT and its analogs. Biochem Biophys Res Commun. 2004 Oct 15;323(2):712-9.
38 IsCT, a novel cytotoxic linear peptide from scorpion Opisthacanthus madagascariensis. Biochem Biophys Res Commun. 2001 Aug 31;286(4):820-5.
39 Cell selectivity and anti-inflammatory activity of a Leu/Lys-rich alpha-helical model antimicrobial peptide and its diastereomeric peptides. Peptides. 2010 Jul;31(7):1251-61.
40 Small cationic protein from a marine turtle has beta-defensin-like fold and antibacterial and antiviral activity. Proteins. 2006 Aug 1;64(2):524-31.
41 Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain. Eur J Biochem. 2003 May;270(9):2068-81.
42 Isolation of dermatoxin from frog skin, an antibacterial peptide encoded by a novel member of the dermaseptin genes family. Eur J Biochem. 2000 Jul;267(14):4583-92.
43 Molecular evolution of the Cecropin multigene family in Drosophilafunctional genes vspseudogenes. Genetics. 1998 Sep;150(1):157-71.
44 Evolutionary history and mechanism of the Drosophila cecropin gene family. Immunogenetics. 1998 May;47(6):417-29.
45 Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis. Science. 2003 Mar 28;299(5615):2071-4.
46 Bactericidal and bacteriolytic action of peptide antibiotic AS-48 against gram-positive and gram-negative bacteria and other organisms. Res Microbiol. 1989 Jan;140(1):57-68.
47 Novel antimicrobial peptides derived from flatfish genes. Antimicrob Agents Chemother. 2003 Aug;47(8):2464-70.
48 Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken. FEBS J. 2006 Jun;273(12):2581-93.
49 CMAP27, a novel chicken cathelicidin-like antimicrobial protein. Vet Immunol Immunopathol. 2005 Jul 15;106(3-4):321-7.
50 Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities. FEBS J. 2007 Jan;274(2):418-28.
51 Antimicrobial peptides from the skin of a Korean frog, Rana rugosa. Biochem Biophys Res Commun. 1994 Nov 30;205(1):948-54.
52 Solution structure and membrane interaction mode of an antimicrobial peptide gaegurin 4. Biochem Biophys Res Commun. 2007 Jan 19;352(3):592-7.
53 Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus). Reproduction. 2007 Jan;133(1):127-33.
54 Purification and characterization of YFGAP, a GAPDH-related novel antimicrobial peptide, from the skin of yellowfin tuna, Thunnus albacares. Fish Shellfish Immunol. 2012 Oct;33(4):743-52.
55 Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4. Eur J Biochem. 2002 Sep;269(17):4367-74.
56 Further isolation and characterization of grammistins from the skin secretion of the soapfish Grammistes sexlineatus. Toxicon. 2005 Apr;45(5):595-601.
57 Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus. Eur J Biochem. 2000 Aug;267(16):5023-31.
58 Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence. Dev Comp Immunol. 2009 Apr;33(4):559-69.
59 Hydramacin-1, structure and antibacterial activity of a protein from the basal metazoan Hydra. J Biol Chem. 2009 Jan 16;284(3):1896-905.
60 Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphosphocholine and sodium dodecyl sulfate micelles. Biochemistry. 2000 Dec 26;39(51):15765-74.
61 Primary structure and in vitro antibacterial properties of the Drosophila melanogaster attacin C Pro-domain. J Biol Chem. 2004 Apr 9;279(15):14853-9.
62 Antimicrobial activity spectrum, cDNA cloning, and mRNA expression of a newly isolated member of the cecropin family from the mosquito vector Aedes aegypti. J Biol Chem. 1999 Jul 16;274(29):20092-7.
63 A Kunitz proteinase inhibitor from corms of Xanthosoma blandum with bactericidal activity. J Nat Prod. 2011 May 27;74(5):969-75.
64 Evaluation of an antimicrobial L-amino acid oxidase and peptide derivatives from Bothropoides mattogrosensis pitviper venom. PLoS One. 2012;7(3):e33639.
65 Structural characterization of de novo designed L5K5W model peptide isomers with potent antimicrobial and varied hemolytic activities. Molecules. 2013 Jan 11;18(1):859-76.
66 High specific selectivity and membrane-active mechanism of synthetic cationic hybrid antimicrobial peptides based on the peptide FV7. Int J Mol Sci. 2017 Feb 6;18(2).
67 Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region. J Am Chem Soc. 2006 May 3;128(17):5776-85.
68 Solution structure of peptide toxins that block mechanosensitive ion channels. J Biol Chem. 2002 Sep 13;277(37):34443-50.
69 Structure and mode of action of microcin 7, an antibacterial peptide produced by Escherichia coli. Antimicrob Agents Chemother. 1985 May;27(5):791-7.
70 Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity. J Biol Chem. 2004 Jul 2;279(27):28233-42.
71 Genetic analysis and complete primary structure of microcin L. Antimicrob Agents Chemother. 2004 Feb;48(2):505-13.
72 Wild-type Escherichia coli producing microcins B17, D93, J25, and L; cloning of genes for microcin L production and immunity. Can J Microbiol. 2003 May;49(5):357-61.
73 A novel antimicrobial peptide from the loach, Misgurnus anguillicaudatus. FEBS Lett. 1997 Jul 14;411(2-3):173-8.
74 Myxinidin, a novel antimicrobial peptide from the epidermal mucus of hagfish, Myxine glutinosa L. Mar Biotechnol (NY). 2009 Nov-Dec;11(6):748-57.
75 Rat neutrophil defensinsPrecursor structures and expression during neutrophilic myelopoiesis. J Immunol. 1995 Nov 1;155(9):4476-84.
76 Polymorphic expression of defensins in neutrophils from outbred rats. Infect Immun. 1990 Dec;58(12):3899-902.
77 Design and mechanism of action of a novel bacteria-selective antimicrobial peptide from the cell-penetrating peptide Pep-1. Biochem Biophys Res Commun. 2006 Oct 20;349(2):769-74.
78 Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin. Arch Biochem Biophys. 2005 Feb 15;434(2):358-64.
79 Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass. J Biol Chem. 2002 Feb 15;277(7):5030-9.
80 Cloning and characterization of a plant defensin VaD1 from azuki bean. J Agric Food Chem. 2005 Feb 23;53(4):982-8.
81 Efficient screening of a novel antimicrobial peptide from Jatropha curcas by cell membrane affinity chromatography. J Agric Food Chem. 2011 Feb 23;59(4):1145-51.
82 The plasticins: membrane adsorption, lipid disorders, and biological activity. Biochemistry. 2006 Dec 5;45(48):14285-97.
83 Isolation and characterization of pleurocidin, an antimicrobial peptide in the skin secretions of winter flounder. J Biol Chem. 1997 May 2;272(18):12008-13.
84 Cloning and developmental expression of a family of pleurocidin-like antimicrobial peptides from winter flounder, Pleuronectes americanus (Walbaum). Dev Comp Immunol. 2001 Mar;25(2):137-47.
85 Identification, structure and differential expression of novel pleurocidins clustered on the genome of the winter flounder, Pseudopleuronectes americanus (Walbaum). Eur J Biochem. 2003 Sep;270(18):3720-30.
86 Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I. Biochim Biophys Acta. 2004 May 6;1698(2):239-50.
87 Antimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: chemical structures and biological activity. J Biochem. 1989 Oct;106(4):663-8.
88 Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. J Biol Chem. 2001 May 25;276(21):17823-9.
89 Porcine beta-defensin 2 displays broad antimicrobial activity against pathogenic intestinal bacteria. Mol Immunol. 2008 Jan;45(2):386-94.
90 Structural studies on the forward and reverse binding modes of peptides to the chaperone DnaK. J Mol Biol. 2013 Jul 24;425(14):2463-79.
91 Characterization of a defensin from the oyster Crassostrea gigasRecombinant production, folding, solution structure, antimicrobial activities, and gene expression. J Biol Chem. 2006 Jan 6;281(1):313-23.
92 A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science. 1999 Oct 15;286(5439):498-502.
93 Characterization and cDNA cloning of two glycine- and histidine-rich antimicrobial peptides from the roots of shepherd's purse, Capsella bursa-pastoris. Plant Mol Biol. 2000 Sep;44(2):187-97.
94 Structure-activity analysis of SMAP-29, a sheep leukocytes-derived antimicrobial peptide. Biochem Biophys Res Commun. 2001 Jul 27;285(4):1046-51.
95 Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus. J Biol Chem. 2003 Dec 19;278(51):51053-8.
96 Solution structure of spheniscin, a beta-defensin from the penguin stomach. J Biol Chem. 2004 Jul 16;279(29):30433-9.
97 Isolation and characterization of gomesin, an 18-residue cysteine-rich defense peptide from the spider Acanthoscurria gomesiana hemocytes with sequence similarities to horseshoe crab antimicrobial peptides of the tachyplesin family. J Biol Chem. 2000 Oct 27;275(43):33464-70.
98 Insect immunity. Constitutive expression of a cysteine-rich antifungal and a linear antibacterial peptide in a termite insect. J Biol Chem. 2001 Feb 9;276(6):4085-92.
99 Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation. Biopolymers. 2006 Feb 5;81(2):92-103.
100 Epithelial innate immunityA novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans. J Biol Chem. 2002 Dec 20;277(51):49921-6.
101 Styelins, broad-spectrum antimicrobial peptides from the solitary tunicate, Styela clava. Comp Biochem Physiol B Biochem Mol Biol. 1997 Nov;118(3):515-21.
102 Tachycitin, a small granular component in horseshoe crab hemocytes, is an antimicrobial protein with chitin-binding activity. J Biochem. 1996 Dec;120(6):1253-60.
103 Chitin-binding proteins in invertebrates and plants comprise a common chitin-binding structural motif. J Biol Chem. 2000 Jun 16;275(24):17929-32.
104 Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides. Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-5.
105 Solution structure of thanatin, a potent bactericidal and fungicidal insect peptide, determined from proton two-dimensional nuclear magnetic resonance data. Eur J Biochem. 1998 Sep 1;256(2):404-10.
106 Biochemical, structural, and genetic characterization of tridecaptin A? an antagonist of Campylobacter jejuni. Chembiochem. 2014 Jan 24;15(2):243-9.
107 Conformation-dependent antibiotic activity of tritrpticin, a cathelicidin-derived antimicrobial peptide. Biochem Biophys Res Commun. 2002 Sep 6;296(5):1044-50.
108 Rational design of alpha-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index. J Biol Chem. 2005 Apr 1;280(13):12316-29.
109 Structural and functional characterization of two genetically related meucin peptides highlights evolutionary divergence and convergence in antimicrobial peptides. FASEB J. 2009 Apr;23(4):1230-45.
110 Anti-biofilm activity of an exopolysaccharide from a sponge-associated strain of Bacillus licheniformis. Microb Cell Fact. 2011 Sep 27;10:74.
111 Anti-biofilm effects of anthranilate on a broad range of bacteria. Sci Rep. 2017 Aug 17;7(1):8604.
112 The natural antimicrobial carvacrol inhibits quorum sensing in Chromobacterium violaceum and reduces bacterial biofilm formation at sub-lethal concentrations. PLoS One. 2014 Apr 1;9(4):e93414.
113 Structure-activity relationship of brominated 3-alkyl-5-methylene-2(5H)-furanones and alkylmaleic anhydrides as inhibitors of Salmonella biofilm formation and quorum sensing regulated bioluminescence in Vibrio harveyi. Bioorg Med Chem. 2010 Jul 15;18(14):5224-33.

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