Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03162)
Xenobiotics Name
Dermaseptin-like PBN2
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Escherichia coli [1]
L,D-carboxypeptidase A (ldcA) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Klebsiella variicola [1]
Beta-lactamase (blaB) DME Info Escherichia coli [1]
Beta-lactamase (blaB) DME Info Salmonella enterica [1]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [1]
Beta-lactamase (blaB) DME Info Enterobacter cloacae [1]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [1]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [1]
Cytidine deaminase (cdd) DME Info Escherichia coli [1]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [1]
Chloramphenicolase (chlR) DME Info Escherichia coli [1]
Glycoside hydrolase (cscA) DME Info Escherichia coli [1]
NADPH-dependent curcumin reductase (curA) DME Info Escherichia coli [1]
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [1]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [1]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [1]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [1]
Unclear metabolic mechanism (DME-unclear) DME Info Escherichia coli [1]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [1]
Unclear metabolic mechanism (DME-unclear) DME Info Salmonella enterica [1]
Glutamate decarboxylase (gadB) DME Info Escherichia coli [1]
Beta-galactosidase (bgaB) DME Info Enterobacter cloacae [1]
D-Lactate dehydrogenase (ldhA) DME Info Escherichia coli [1]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [1]
Molybdopterin-dependent enzyme (molD) DME Info Escherichia coli [1]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [1]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [1]
Glutamate racemase (MurI) DME Info Escherichia coli [1]
N-ethylmaleimide reductase (nemA) DME Info Escherichia coli [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info Salmonella enterica [1]
Nitroreductase (NTR) DME Info Enterobacter cloacae [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Escherichia coli [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info Salmonella enterica [1]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [1]
NADH dehydrogenase (nuoE) DME Info Streptomyces griseus [1]
Retro-nitroreductase (rNR) DME Info Enterobacter cloacae [1]
Tyramine oxidase (tynA) DME Info Escherichia coli [1]
Beta-glucuronidase (uidA) DME Info Escherichia coli [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 1.5 microM [1]
L,D-carboxypeptidase A (ldcA) DME Info MIC = 1.5 microM [1]
Beta-lactamase (blaB) DME Info MIC = 0.8 microM [1]
Beta-lactamase (blaB) DME Info MIC = 1.5 microM [1]
Beta-lactamase (blaB) DME Info MIC = 3.1 microM [1]
Beta-lactamase (blaB) DME Info MIC = 0.8 microM [1]
Beta-lactamase (blaB) DME Info MIC = 12.5 microM [1]
Metallo-beta-lactamase (blaM) DME Info MIC = 0.8 microM [1]
Beta-lactamase (blaB) DME Info MIC = 0.8 microM [1]
Cytidine deaminase (cdd) DME Info MIC = 0.8 microM [1]
Cytidine deaminase (cdd) DME Info MIC = 0.8 microM [1]
Chloramphenicolase (chlR) DME Info MIC = 1.5 microM [1]
Glycoside hydrolase (cscA) DME Info MIC = 1.5 microM [1]
NADPH-dependent curcumin reductase (curA) DME Info MIC = 1.5 microM [1]
Cytochrome P450 102A1 (cyp102) DME Info MIC = 0.8 microM [1]
Cytochrome P450 MEG (cyp106) DME Info MIC = 0.8 microM [1]
Cytochrome P450 21A2 (cyp21) DME Info MIC = 0.8 microM [1]
Cytochrome P450 BM3 (cypBM3) DME Info MIC = 0.8 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 1.5 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 0.8 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 3.1 microM [1]
Glutamate decarboxylase (gadB) DME Info MIC = 1.5 microM [1]
Beta-galactosidase (bgaB) DME Info MIC = 12.5 microM [1]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 1.5 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 0.8 microM [1]
Molybdopterin-dependent enzyme (molD) DME Info MIC = 1.5 microM [1]
Methylthioribose kinase (mtnK) DME Info MIC = 0.8 microM [1]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info MIC = 0.8 microM [1]
Glutamate racemase (MurI) DME Info MIC = 1.5 microM [1]
N-ethylmaleimide reductase (nemA) DME Info MIC = 1.5 microM [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 3.1 microM [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 1.5 microM [1]
Oxygen-insensitive NADPH nitroreductase A (nfsA) DME Info MIC = 3.1 microM [1]
Nitroreductase (NTR) DME Info MIC = 12.5 microM [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 1.5 microM [1]
Oxygen-insensitive NADPH nitroreductase B (nfsB) DME Info MIC = 3.1 microM [1]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 0.8 microM [1]
NADH dehydrogenase (nuoE) DME Info MIC = 1.5 microM [1]
Retro-nitroreductase (rNR) DME Info MIC = 12.5 microM [1]
Tyramine oxidase (tynA) DME Info MIC = 1.5 microM [1]
Beta-glucuronidase (uidA) DME Info MIC = 1.5 microM [1]
References
1 Antimicrobial peptides from hylid and ranin frogs originated from a 150-million-year-old ancestral precursor with a conserved signal peptide but a hypermutable antimicrobial domain. Eur J Biochem. 2003 May;270(9):2068-81.

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